ZA942803B - Improved water dispersible pharmaceutical compositions - Google Patents
Improved water dispersible pharmaceutical compositionsInfo
- Publication number
- ZA942803B ZA942803B ZA942803A ZA942803A ZA942803B ZA 942803 B ZA942803 B ZA 942803B ZA 942803 A ZA942803 A ZA 942803A ZA 942803 A ZA942803 A ZA 942803A ZA 942803 B ZA942803 B ZA 942803B
- Authority
- ZA
- South Africa
- Prior art keywords
- pct
- pharmaceutical compositions
- water dispersible
- improved water
- dispersible pharmaceutical
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ247516A NZ247516A (en) | 1993-04-28 | 1993-04-28 | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA942803B true ZA942803B (en) | 1996-01-22 |
Family
ID=19924336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA942803A ZA942803B (en) | 1993-04-28 | 1994-04-22 | Improved water dispersible pharmaceutical compositions |
Country Status (19)
Country | Link |
---|---|
US (1) | US5843891A (xx) |
EP (1) | EP0696920B1 (xx) |
JP (1) | JPH08509475A (xx) |
CN (1) | CN1124457A (xx) |
AT (1) | ATE173635T1 (xx) |
AU (1) | AU677660B2 (xx) |
BR (1) | BR9406513A (xx) |
CA (1) | CA2160880A1 (xx) |
CZ (1) | CZ276995A3 (xx) |
DE (1) | DE69414840T2 (xx) |
FI (1) | FI955091A (xx) |
HU (1) | HUT73664A (xx) |
IL (1) | IL109401A0 (xx) |
MX (1) | MX9402922A (xx) |
NO (1) | NO954329L (xx) |
NZ (1) | NZ247516A (xx) |
PL (1) | PL311294A1 (xx) |
WO (1) | WO1994025068A1 (xx) |
ZA (1) | ZA942803B (xx) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
JP4718653B2 (ja) * | 1997-03-12 | 2011-07-06 | アボツト・ラボラトリーズ | シクロスポリンの投与のための親水性二成分系 |
US6258783B1 (en) | 1997-04-29 | 2001-07-10 | Bernard Charles Sherman | Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride |
NZ314702A (en) * | 1997-04-29 | 1998-07-28 | Bernard Charles Sherman | Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent |
FR2764509A1 (fr) * | 1997-06-11 | 1998-12-18 | Debiopharm Sa | Compositions pharmaceutiques contenant du dichlorhydrate de cinchonine |
WO1999029316A1 (en) | 1997-12-10 | 1999-06-17 | Severson, Mary, L. | Pharmaceutical compositions containing an omega-3 fatty acid oil |
US20030216303A1 (en) * | 1998-03-06 | 2003-11-20 | Michael Ambuhl | Emulsion preconcentrates containing cyclosporin or a macrolide |
US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
AU2002240755B2 (en) * | 2001-03-13 | 2007-07-05 | Angiotech International Ag | Micellar drug delivery vehicles and uses thereof |
US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
NZ529647A (en) * | 2001-04-20 | 2007-05-31 | Univ British Columbia | Micellar drug delivery systems for hydrophobic drugs |
US6592899B2 (en) | 2001-10-03 | 2003-07-15 | Macromed Incorporated | PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water |
CA2461730C (en) * | 2001-10-19 | 2012-05-15 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
WO2003053404A1 (en) * | 2001-12-20 | 2003-07-03 | Bernard Charles Sherman | Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
WO2005053727A2 (en) * | 2003-11-29 | 2005-06-16 | Sangstat Medical Corporation | Pharmaceutical compositions for bioactive peptide agents |
US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2006082588A2 (en) * | 2005-02-07 | 2006-08-10 | Pharmalight Inc. | Method and device for ophthalmic administration of active pharmaceutical ingredients |
MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
EP2363112B8 (en) | 2006-08-09 | 2018-11-21 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
TWI394564B (zh) * | 2006-09-21 | 2013-05-01 | Alcon Res Ltd | 自行保存型水性藥學組成物 |
EP2157967B1 (en) | 2007-04-23 | 2013-01-16 | Intarcia Therapeutics, Inc | Suspension formulations of insulinotropic peptides and uses thereof |
EP2200613B1 (en) | 2007-09-21 | 2018-09-05 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
CA3014633C (en) | 2007-10-08 | 2022-05-17 | Aurinia Pharmaceuticals Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors |
US8343140B2 (en) | 2008-02-13 | 2013-01-01 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
US8906414B1 (en) | 2009-04-27 | 2014-12-09 | University Of South Florida | Methods and compositions for improving bioavailability of epigallocatechin gallate (EGCG) |
JP2012529509A (ja) | 2009-06-09 | 2012-11-22 | ラックス・バイオサイエンシーズ・インコーポレイテッド | 眼科用用途のための局所薬物送達システム |
AU2010298733B2 (en) | 2009-09-28 | 2014-10-09 | Intarcia Therapeutics, Inc. | Rapid establishment and/or termination of substantial steady-state drug delivery |
US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
KR101211902B1 (ko) | 2012-04-30 | 2012-12-13 | 주식회사 휴온스 | 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물 |
HUE062145T2 (hu) * | 2012-08-24 | 2023-10-28 | Sun Pharmaceutical Ind Ltd | Polioxil lipid vagy polioxil zsírsav szemészeti készítménye és szemészeti állapotok kezelése |
US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
US9498485B2 (en) | 2014-08-28 | 2016-11-22 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
US10016363B2 (en) | 2014-09-18 | 2018-07-10 | Virun, Inc. | Pre-spray emulsions and powders containing non-polar compounds |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
EP3302354B1 (en) | 2015-06-03 | 2023-10-04 | i2o Therapeutics, Inc. | Implant placement systems |
AU2016351588A1 (en) | 2015-11-10 | 2018-05-24 | Sun Pharma Global Fze | Topical formulations and uses thereof |
BR112018067946A8 (pt) | 2016-02-29 | 2022-11-08 | Sun Pharma Global Fze | Formulações tópicas contendo ciclosporina e usos das mesmas |
RU2760007C2 (ru) | 2016-05-16 | 2021-11-22 | Интарсия Терапьютикс, Инк. | Полипептиды, селективные к рецепторам глюкагона, и способы их применения |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
CA3078723A1 (en) | 2016-11-28 | 2018-05-31 | Nachiappan Chidambaram | Oral testosterone undecanoate therapy |
IL307966A (en) | 2017-01-03 | 2023-12-01 | Intarcia Therapeutics Inc | Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug |
US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
WO2024111590A1 (ja) * | 2022-11-22 | 2024-05-30 | 一丸ファルコス株式会社 | Ras阻害ペプチドを含む組成物 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS498246B1 (xx) * | 1965-07-15 | 1974-02-25 | ||
JPS5919525B2 (ja) * | 1976-09-03 | 1984-05-07 | 武田薬品工業株式会社 | 注射剤 |
FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
GB8903804D0 (en) * | 1989-02-20 | 1989-04-05 | Sandoz Ltd | Improvements in or relating to organic compounds |
JPS6226220A (ja) * | 1985-07-29 | 1987-02-04 | Hishiyama Seiyaku Kk | ケトプロフエン注射液 |
JP2577049B2 (ja) * | 1987-06-04 | 1997-01-29 | 三共株式会社 | シクロスポリン製剤 |
CH679119A5 (xx) * | 1988-05-13 | 1991-12-31 | Sandoz Ag | |
GB2222770B (en) * | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
HU208491B (en) * | 1990-11-27 | 1993-11-29 | Gyogyszerkutato Intezet | Process for producing oral pharmaceutical composition containing cyclosporin |
GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
JPH0558906A (ja) * | 1991-09-06 | 1993-03-09 | Sankyo Co Ltd | シクロスポリン点眼製剤 |
-
1993
- 1993-04-28 NZ NZ247516A patent/NZ247516A/en unknown
-
1994
- 1994-04-22 AU AU66734/94A patent/AU677660B2/en not_active Ceased
- 1994-04-22 CA CA002160880A patent/CA2160880A1/en not_active Abandoned
- 1994-04-22 US US08/537,697 patent/US5843891A/en not_active Expired - Fee Related
- 1994-04-22 CN CN94192265A patent/CN1124457A/zh active Pending
- 1994-04-22 BR BR9406513A patent/BR9406513A/pt not_active Application Discontinuation
- 1994-04-22 JP JP6523695A patent/JPH08509475A/ja active Pending
- 1994-04-22 AT AT94914284T patent/ATE173635T1/de not_active IP Right Cessation
- 1994-04-22 HU HU9503075A patent/HUT73664A/hu unknown
- 1994-04-22 ZA ZA942803A patent/ZA942803B/xx unknown
- 1994-04-22 MX MX9402922A patent/MX9402922A/es not_active Application Discontinuation
- 1994-04-22 WO PCT/CA1994/000222 patent/WO1994025068A1/en not_active Application Discontinuation
- 1994-04-22 EP EP94914284A patent/EP0696920B1/en not_active Expired - Lifetime
- 1994-04-22 IL IL10940194A patent/IL109401A0/xx unknown
- 1994-04-22 CZ CZ952769A patent/CZ276995A3/cs unknown
- 1994-04-22 PL PL94311294A patent/PL311294A1/xx unknown
- 1994-04-22 DE DE69414840T patent/DE69414840T2/de not_active Expired - Fee Related
-
1995
- 1995-10-25 FI FI955091A patent/FI955091A/fi not_active Application Discontinuation
- 1995-10-27 NO NO954329A patent/NO954329L/no unknown
Also Published As
Publication number | Publication date |
---|---|
HU9503075D0 (en) | 1995-12-28 |
FI955091A (fi) | 1995-12-14 |
MX9402922A (es) | 1997-05-31 |
IL109401A0 (en) | 1994-11-28 |
US5843891A (en) | 1998-12-01 |
EP0696920A1 (en) | 1996-02-21 |
AU6673494A (en) | 1994-11-21 |
CA2160880A1 (en) | 1994-11-10 |
PL311294A1 (en) | 1996-02-05 |
DE69414840T2 (de) | 1999-04-22 |
BR9406513A (pt) | 1996-01-09 |
NO954329D0 (no) | 1995-10-27 |
EP0696920B1 (en) | 1998-11-25 |
HUT73664A (en) | 1996-09-30 |
AU677660B2 (en) | 1997-05-01 |
JPH08509475A (ja) | 1996-10-08 |
NO954329L (no) | 1995-12-21 |
CN1124457A (zh) | 1996-06-12 |
NZ247516A (en) | 1995-02-24 |
ATE173635T1 (de) | 1998-12-15 |
CZ276995A3 (en) | 1996-03-13 |
FI955091A0 (fi) | 1995-10-25 |
DE69414840D1 (de) | 1999-01-07 |
WO1994025068A1 (en) | 1994-11-10 |
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