ZA942429B - Improved process for manufacturing L(-) carnitine from a product having opposite configuration - Google Patents
Improved process for manufacturing L(-) carnitine from a product having opposite configurationInfo
- Publication number
- ZA942429B ZA942429B ZA942429A ZA942429A ZA942429B ZA 942429 B ZA942429 B ZA 942429B ZA 942429 A ZA942429 A ZA 942429A ZA 942429 A ZA942429 A ZA 942429A ZA 942429 B ZA942429 B ZA 942429B
- Authority
- ZA
- South Africa
- Prior art keywords
- carnitine
- manufacturing
- product
- improved process
- opposite configuration
- Prior art date
Links
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Processing Of Solid Wastes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM930227A IT1261231B (it) | 1993-04-08 | 1993-04-08 | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA942429B true ZA942429B (en) | 1994-11-29 |
Family
ID=11401705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA942429A ZA942429B (en) | 1993-04-08 | 1994-04-08 | Improved process for manufacturing L(-) carnitine from a product having opposite configuration |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5532410A (enExample) |
| EP (1) | EP0624568B1 (enExample) |
| JP (1) | JP3635102B2 (enExample) |
| KR (1) | KR100301952B1 (enExample) |
| AT (1) | ATE145641T1 (enExample) |
| CA (1) | CA2120812C (enExample) |
| DE (1) | DE69400978T2 (enExample) |
| DK (1) | DK0624568T3 (enExample) |
| ES (1) | ES2095144T3 (enExample) |
| GR (1) | GR3021790T3 (enExample) |
| IT (1) | IT1261231B (enExample) |
| TW (1) | TW284753B (enExample) |
| ZA (1) | ZA942429B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1276207B1 (it) * | 1995-09-29 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone |
| IT1297120B1 (it) * | 1997-12-16 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina |
| IT1306184B1 (it) * | 1999-08-05 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Nitrilossi derivati della (r) e (s)-carnitina. |
| EP2409965A1 (en) * | 2010-07-21 | 2012-01-25 | Lonza Ltd. | A process for the production of carnitine by cycloaddition |
| CN108863845B (zh) * | 2018-08-21 | 2021-01-01 | 湖南大学 | 一种肟菌酯及其中间体的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3096368A (en) * | 1958-07-30 | 1963-07-02 | Process for preparing hydrolysis products of gamma-dimethyl amin-beta-hydroxybutyroni | |
| IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
| IT1144077B (it) * | 1980-01-29 | 1986-10-29 | Sigma Tau Ind Farmaceuti | Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione |
| IT1136945B (it) * | 1981-03-18 | 1986-09-03 | Anic Spa | Processo per la preparazione di l-carnitina |
| IT1191945B (it) * | 1986-06-04 | 1988-03-31 | Avantgarde Spa | N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono |
| JPH0291049A (ja) * | 1988-09-21 | 1990-03-30 | Lonza Ag | ｒ―ブチロベタインの製造方法 |
| IT1258370B (it) * | 1992-03-02 | 1996-02-26 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono. |
-
1993
- 1993-04-08 IT ITRM930227A patent/IT1261231B/it active IP Right Grant
-
1994
- 1994-03-31 ES ES94830151T patent/ES2095144T3/es not_active Expired - Lifetime
- 1994-03-31 DK DK94830151.0T patent/DK0624568T3/da active
- 1994-03-31 EP EP94830151A patent/EP0624568B1/en not_active Expired - Lifetime
- 1994-03-31 AT AT94830151T patent/ATE145641T1/de not_active IP Right Cessation
- 1994-03-31 DE DE69400978T patent/DE69400978T2/de not_active Expired - Lifetime
- 1994-04-04 US US08/224,513 patent/US5532410A/en not_active Expired - Lifetime
- 1994-04-07 JP JP06928794A patent/JP3635102B2/ja not_active Expired - Fee Related
- 1994-04-07 KR KR1019940007251A patent/KR100301952B1/ko not_active Expired - Fee Related
- 1994-04-07 CA CA002120812A patent/CA2120812C/en not_active Expired - Fee Related
- 1994-04-07 TW TW083103009A patent/TW284753B/zh active
- 1994-04-08 ZA ZA942429A patent/ZA942429B/xx unknown
-
1996
- 1996-11-28 GR GR960402830T patent/GR3021790T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0624568B1 (en) | 1996-11-27 |
| JP3635102B2 (ja) | 2005-04-06 |
| HK1005723A1 (en) | 1999-01-22 |
| ITRM930227A1 (it) | 1994-10-08 |
| IT1261231B (it) | 1996-05-09 |
| CA2120812C (en) | 2004-10-26 |
| JPH06306028A (ja) | 1994-11-01 |
| TW284753B (enExample) | 1996-09-01 |
| GR3021790T3 (en) | 1997-02-28 |
| EP0624568A1 (en) | 1994-11-17 |
| DE69400978D1 (de) | 1997-01-09 |
| CA2120812A1 (en) | 1994-10-09 |
| DE69400978T2 (de) | 1997-04-03 |
| KR100301952B1 (ko) | 2001-10-22 |
| ITRM930227A0 (it) | 1993-04-08 |
| US5532410A (en) | 1996-07-02 |
| ES2095144T3 (es) | 1997-02-01 |
| DK0624568T3 (da) | 1996-12-16 |
| ATE145641T1 (de) | 1996-12-15 |
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