IT1144077B - Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione - Google Patents

Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione

Info

Publication number
IT1144077B
IT1144077B IT47749/80A IT4774980A IT1144077B IT 1144077 B IT1144077 B IT 1144077B IT 47749/80 A IT47749/80 A IT 47749/80A IT 4774980 A IT4774980 A IT 4774980A IT 1144077 B IT1144077 B IT 1144077B
Authority
IT
Italy
Prior art keywords
carnitinamides
procedure
preparation
amino acids
optically active
Prior art date
Application number
IT47749/80A
Other languages
English (en)
Other versions
IT8047749A0 (it
Inventor
Paolo De Witt
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IT8047749A0 publication Critical patent/IT8047749A0/it
Priority to IT47749/80A priority Critical patent/IT1144077B/it
Priority to US06/220,492 priority patent/US4343947A/en
Priority to DE3100133A priority patent/DE3100133A1/de
Priority to BE0/203511A priority patent/BE887112A/fr
Priority to CA000368952A priority patent/CA1167453A/en
Priority to JP954981A priority patent/JPS56110654A/ja
Priority to FR8101593A priority patent/FR2474489A1/fr
Priority to ES498881A priority patent/ES8207128A1/es
Priority to CH560/81A priority patent/CH651015A5/it
Priority to GB8102766A priority patent/GB2068946B/en
Application granted granted Critical
Publication of IT1144077B publication Critical patent/IT1144077B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
IT47749/80A 1980-01-29 1980-01-29 Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione IT1144077B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT47749/80A IT1144077B (it) 1980-01-29 1980-01-29 Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione
US06/220,492 US4343947A (en) 1980-01-29 1980-12-29 Carnitinamides of optically active aminoacids
DE3100133A DE3100133A1 (de) 1980-01-29 1981-01-05 Carnitinamide von optisch aktiven aminosaeuren, verfahren zu ihrer herstellung sowie arzneimittel
BE0/203511A BE887112A (fr) 1980-01-29 1981-01-16 Carnitinamides d'aminoacides optiquement actifs et leur preparation
CA000368952A CA1167453A (en) 1980-01-29 1981-01-21 Carnitinamides of optically active aminoacids and process for preparing same
JP954981A JPS56110654A (en) 1980-01-29 1981-01-23 Carnitine amide derivative of amino acid and its manufacture
FR8101593A FR2474489A1 (fr) 1980-01-29 1981-01-28 Carnitinamides d'aminoacides optiquement actifs, leur procede de preparation et leur application en therapeutique
ES498881A ES8207128A1 (es) 1980-01-29 1981-01-28 Procedimiento para preparar carnitinamidas
CH560/81A CH651015A5 (it) 1980-01-29 1981-01-28 Carnitinammidi di amminoacidi otticamente attivi e procedimenti per la loro preparazione.
GB8102766A GB2068946B (en) 1980-01-29 1981-01-29 Carnitinamides of optically active aminoacids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47749/80A IT1144077B (it) 1980-01-29 1980-01-29 Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
IT8047749A0 IT8047749A0 (it) 1980-01-29
IT1144077B true IT1144077B (it) 1986-10-29

Family

ID=11262265

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47749/80A IT1144077B (it) 1980-01-29 1980-01-29 Carnitinammidi di amminoacidi otticamente attivi e procedimento per la loro preparazione

Country Status (10)

Country Link
US (1) US4343947A (it)
JP (1) JPS56110654A (it)
BE (1) BE887112A (it)
CA (1) CA1167453A (it)
CH (1) CH651015A5 (it)
DE (1) DE3100133A1 (it)
ES (1) ES8207128A1 (it)
FR (1) FR2474489A1 (it)
GB (1) GB2068946B (it)
IT (1) IT1144077B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1248323B (it) * 1991-05-16 1995-01-05 Sigma Tau Ind Farmaceuti Ammidi con amminoacidi naturali di alcanoil l-carnitine quali inibitori della degenerazione neuronale e attivatori dei processi di apprendimento e memorizzazione e per il trattamento del coma e composizioni farmaceutiche comprendenti tali composti
IT1261231B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.
US5958886A (en) * 1998-01-13 1999-09-28 Sigma-Tau Pharmaceuticals, Inc. Carnitine-containing peptides and a method for using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265719A (en) * 1959-12-28 1966-08-09 American Cyanamid Co Betaines
US3979441A (en) * 1969-06-11 1976-09-07 The Lubrizol Corporation Oil-soluble polymers of N-3-aminoalkyl acrylamides, and lubricants containing them
US4116962A (en) * 1976-12-03 1978-09-26 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins

Also Published As

Publication number Publication date
GB2068946A (en) 1981-08-19
JPS56110654A (en) 1981-09-01
FR2474489B1 (it) 1984-05-18
JPH034539B2 (it) 1991-01-23
BE887112A (fr) 1981-05-14
CH651015A5 (it) 1985-08-30
GB2068946B (en) 1983-07-13
ES498881A0 (es) 1982-09-01
DE3100133A1 (de) 1981-11-19
FR2474489A1 (fr) 1981-07-31
ES8207128A1 (es) 1982-09-01
IT8047749A0 (it) 1980-01-29
US4343947A (en) 1982-08-10
CA1167453A (en) 1984-05-15

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Effective date: 19931202