ZA938350B - Antineoplastic heteronaphthoquinones - Google Patents

Antineoplastic heteronaphthoquinones

Info

Publication number
ZA938350B
ZA938350B ZA938350A ZA938350A ZA938350B ZA 938350 B ZA938350 B ZA 938350B ZA 938350 A ZA938350 A ZA 938350A ZA 938350 A ZA938350 A ZA 938350A ZA 938350 B ZA938350 B ZA 938350B
Authority
ZA
South Africa
Prior art keywords
heteronaphthoquinones
antineoplastic
antineoplastic heteronaphthoquinones
Prior art date
Application number
ZA938350A
Other languages
English (en)
Inventor
Giorgio Attardo
Marc Courchesne
Jean-Louis Kraus
Serge Lamothe
Jean-Francois Lavallee
Elaine Lebeau
Dieu Nguyen
Rabindra Rej
Yves St-Denis
Wuyi Wang
Yao-Chaung Xu
Tibor Breining
France Barbeau
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of ZA938350B publication Critical patent/ZA938350B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/08—Naphthothiopyrans; Hydrogenated naphthothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
ZA938350A 1992-11-09 1993-11-09 Antineoplastic heteronaphthoquinones ZA938350B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97323392A 1992-11-09 1992-11-09

Publications (1)

Publication Number Publication Date
ZA938350B true ZA938350B (en) 1994-06-21

Family

ID=25520651

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA938350A ZA938350B (en) 1992-11-09 1993-11-09 Antineoplastic heteronaphthoquinones

Country Status (6)

Country Link
EP (1) EP0659190A1 (xx)
CN (1) CN1094402A (xx)
AU (1) AU5414094A (xx)
CA (1) CA2146548A1 (xx)
WO (1) WO1994011382A1 (xx)
ZA (1) ZA938350B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6672794A (en) * 1993-11-05 1995-05-23 Biochem Pharma Inc. Antineoplastic heteronaphthoquinones
US5883270A (en) * 1996-02-20 1999-03-16 Wisconsin Alumni Research Foundation 4-substituted-1, 2-naphthoquinones and their use in the inhibition of neoplastic cell growth
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
CN102731464B (zh) * 2011-04-12 2014-07-23 沈阳药科大学 一个倍半萜内酯化合物、制备方法及其应用
CN102911177B (zh) * 2012-11-07 2014-07-09 新乡医学院 7-(4-氯苯基)-5,6-二氢-7aH-苯并[h]1,2,4-三氮唑并[3,4-b]喹唑啉-5,6-二酮及其合成方法
CN113278026B (zh) * 2021-05-29 2022-05-13 南京中医药大学 一种具有抗肿瘤活性的苦木素类化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62120379A (ja) * 1985-11-19 1987-06-01 Hoechst Japan Kk フザルビン誘導体およびその製法
AP340A (en) * 1990-06-11 1994-05-13 Iaf Biochem Int Heterocyclic anathracyclinone and anathracycline analogs
NL9001834A (nl) * 1990-08-16 1992-03-16 Pharmachemie Bv Nieuwe antracyclineverbindingen met anti-tumorwerkzaamheid, nieuwe tussenverbindingen voor de bereiding van deze antracyclineverbindingen, alsmede preparaten die de aktieve antracyclineverbindingen bevatten.

Also Published As

Publication number Publication date
WO1994011382A1 (en) 1994-05-26
AU5414094A (en) 1994-06-08
CN1094402A (zh) 1994-11-02
EP0659190A1 (en) 1995-06-28
CA2146548A1 (en) 1994-05-26

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