ZA931746B - Antiherpes peptide derivatives having a ureido N-terminus - Google Patents

Antiherpes peptide derivatives having a ureido N-terminus

Info

Publication number
ZA931746B
ZA931746B ZA931746A ZA931746A ZA931746B ZA 931746 B ZA931746 B ZA 931746B ZA 931746 A ZA931746 A ZA 931746A ZA 931746 A ZA931746 A ZA 931746A ZA 931746 B ZA931746 B ZA 931746B
Authority
ZA
South Africa
Prior art keywords
alkyl
peptide derivatives
nhch
ureido
terminus
Prior art date
Application number
ZA931746A
Other languages
English (en)
Inventor
Robert Deziel
Neil Moss
Raymond Plante
Original Assignee
Bio Mega Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Mega Boehringer Ingelheim filed Critical Bio Mega Boehringer Ingelheim
Publication of ZA931746B publication Critical patent/ZA931746B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA931746A 1992-03-12 1993-03-11 Antiherpes peptide derivatives having a ureido N-terminus ZA931746B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84992292A 1992-03-12 1992-03-12

Publications (1)

Publication Number Publication Date
ZA931746B true ZA931746B (en) 1993-10-06

Family

ID=25306844

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA931746A ZA931746B (en) 1992-03-12 1993-03-11 Antiherpes peptide derivatives having a ureido N-terminus

Country Status (11)

Country Link
EP (1) EP0560274B1 (ja)
JP (1) JPH0641189A (ja)
AT (1) ATE167682T1 (ja)
CA (1) CA2092652C (ja)
DE (2) DE69319266D1 (ja)
HU (1) HUT63853A (ja)
IL (1) IL105002A0 (ja)
NZ (1) NZ247116A (ja)
PL (1) PL298039A1 (ja)
TW (1) TW329426B (ja)
ZA (1) ZA931746B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2152541C (en) * 1995-06-23 1998-12-15 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Herpes ribonucleotide reductase inhibitors
US7087418B2 (en) 2001-12-19 2006-08-08 Bristol-Myers Squibb Company Pichia pastoris formate dehydrogenase and uses therefor
JP5006137B2 (ja) * 2007-08-28 2012-08-22 日本合成化学工業株式会社 イソシアノ酢酸アルキルエステル液状組成物およびその保存方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03181498A (ja) * 1989-12-07 1991-08-07 Merck & Co Inc ペプチド抗ウイルス剤

Also Published As

Publication number Publication date
ATE167682T1 (de) 1998-07-15
NZ247116A (en) 1995-12-21
EP0560274B1 (en) 1998-06-24
AU665059B2 (en) 1995-12-14
HUT63853A (en) 1993-10-28
JPH0641189A (ja) 1994-02-15
DE69319266T4 (de) 2000-04-27
HU9300697D0 (en) 1993-05-28
DE69319266D1 (de) 1998-07-30
AU3516293A (en) 1993-09-16
CA2092652C (en) 2001-07-24
CA2092652A1 (en) 1993-09-13
IL105002A0 (en) 1993-07-08
EP0560274A1 (en) 1993-09-15
DE69319266T2 (de) 1998-11-26
PL298039A1 (en) 1993-11-29
TW329426B (en) 1998-04-11

Similar Documents

Publication Publication Date Title
TW278080B (ja)
ZA931746B (en) Antiherpes peptide derivatives having a ureido N-terminus
ES2152269T3 (es) Inhibidores de ribonucleotido-reductasa de herpesvirus.
IL94981A0 (en) Antiviral peptides having a 2-oxoalkyl side chain,their preparation and pharmaceutical compositions containing them
CA2019005A1 (en) Antiherpes pentapeptide derivatives having a cycloalkyl substituted aspartic acid side chain