ZA929268B - Imidazole compounds, their preparation and use. - Google Patents
Imidazole compounds, their preparation and use.Info
- Publication number
- ZA929268B ZA929268B ZA929268A ZA929268A ZA929268B ZA 929268 B ZA929268 B ZA 929268B ZA 929268 A ZA929268 A ZA 929268A ZA 929268 A ZA929268 A ZA 929268A ZA 929268 B ZA929268 B ZA 929268B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- preparation
- imidazole compounds
- alkoxy
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Resins (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Developing Agents For Electrophotography (AREA)
- Dental Preparations (AREA)
- Lubricants (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80175491A | 1991-12-03 | 1991-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA929268B true ZA929268B (en) | 1993-06-29 |
Family
ID=25181970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA929268A ZA929268B (en) | 1991-12-03 | 1992-11-30 | Imidazole compounds, their preparation and use. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5314903A (xx) |
EP (1) | EP0545845B1 (xx) |
JP (1) | JPH072796A (xx) |
KR (1) | KR100220303B1 (xx) |
AT (1) | ATE134622T1 (xx) |
AU (1) | AU649899B2 (xx) |
CA (1) | CA2084233A1 (xx) |
DE (1) | DE69208604T2 (xx) |
DK (1) | DK0545845T3 (xx) |
ES (1) | ES2084972T3 (xx) |
FI (1) | FI925501A (xx) |
GR (1) | GR3019439T3 (xx) |
NO (1) | NO300832B1 (xx) |
NZ (1) | NZ245287A (xx) |
ZA (1) | ZA929268B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK154092D0 (da) * | 1992-12-23 | 1992-12-23 | Neurosearch As | Imidazolforbindelser, deres fremstilling og anvendelse |
US6194447B1 (en) | 1998-07-02 | 2001-02-27 | Neurosearch A/S | Bis (benzimidazole) derivatives serving as potassium blocking agents |
JP2002519412A (ja) * | 1998-07-02 | 2002-07-02 | ニューロサーチ、アクティーゼルスカブ | カリウムチャンネル遮断剤 |
CA2349616A1 (en) | 1998-12-04 | 2000-06-15 | Neurosearch A/S | New benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents |
WO2004064835A1 (en) * | 2003-01-17 | 2004-08-05 | Neurosearch A/S | Use of ion channel modulating agents for treating pain |
WO2004093813A2 (en) * | 2003-04-22 | 2004-11-04 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of pain, inflammation or inflammation mediated disorders |
WO2004093816A2 (en) * | 2003-04-22 | 2004-11-04 | Pharmacia Corporation | Compositions comprising a selective cox-2 inhibitor and a calcium modulating agent |
US7166603B2 (en) | 2003-07-23 | 2007-01-23 | Bristol-Myers Squibb Co. | Dihydropyrimidone inhibitors of calcium channel function |
US7157461B2 (en) | 2003-07-23 | 2007-01-02 | Bristol-Myers Squibb Co. | Substituted dihydropyrimidine inhibitors of calcium channel function |
DE10342503A1 (de) * | 2003-09-12 | 2005-04-14 | Merck Patent Gmbh | Benzyl-Benzimidazolylderivate |
US7504431B2 (en) | 2004-04-16 | 2009-03-17 | Bristol-Myers Squibb Company | Sulfonyl amide inhibitors of calcium channel function |
EP1917251B1 (de) | 2005-08-21 | 2013-04-03 | Abbott GmbH & Co. KG | 5-ring-heteroaromaten-verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
GB0715103D0 (en) * | 2007-08-03 | 2007-09-12 | Lectus Therapeutics Ltd | Calcium ion channel modulators and uses thereof |
US10501421B1 (en) * | 2017-01-27 | 2019-12-10 | Vanderbilt University | Substituted benzimidazoles as modulators of Ras signaling |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4004016A (en) * | 1975-08-11 | 1977-01-18 | E. R. Squibb & Sons, Inc. | Amino-benzimidazole derivatives |
NZ232396A (en) * | 1989-02-10 | 1991-07-26 | Merrell Dow Pharma | 2-(diphenylalkylamino) -1,3 nn heterocyclic compounds and pharmaceutical compositions |
DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US5210091A (en) * | 1991-06-24 | 1993-05-11 | Neurosearch A/S | Imidazole compounds and their use |
-
1992
- 1992-11-18 US US07/978,131 patent/US5314903A/en not_active Expired - Lifetime
- 1992-11-20 ES ES92610081T patent/ES2084972T3/es not_active Expired - Lifetime
- 1992-11-20 DK DK92610081.9T patent/DK0545845T3/da active
- 1992-11-20 EP EP92610081A patent/EP0545845B1/en not_active Expired - Lifetime
- 1992-11-20 DE DE69208604T patent/DE69208604T2/de not_active Expired - Lifetime
- 1992-11-20 AT AT92610081T patent/ATE134622T1/de not_active IP Right Cessation
- 1992-11-26 AU AU29651/92A patent/AU649899B2/en not_active Ceased
- 1992-11-26 NZ NZ245287A patent/NZ245287A/en not_active IP Right Cessation
- 1992-11-30 ZA ZA929268A patent/ZA929268B/xx unknown
- 1992-12-01 KR KR1019920022960A patent/KR100220303B1/ko not_active IP Right Cessation
- 1992-12-01 CA CA002084233A patent/CA2084233A1/en not_active Abandoned
- 1992-12-02 JP JP4323417A patent/JPH072796A/ja not_active Withdrawn
- 1992-12-02 NO NO924646A patent/NO300832B1/no unknown
- 1992-12-03 FI FI925501A patent/FI925501A/fi unknown
-
1996
- 1996-03-27 GR GR960400825T patent/GR3019439T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2084972T3 (es) | 1996-05-16 |
KR100220303B1 (ko) | 1999-09-15 |
EP0545845B1 (en) | 1996-02-28 |
FI925501A0 (fi) | 1992-12-03 |
DE69208604D1 (de) | 1996-04-04 |
NO300832B1 (no) | 1997-08-04 |
AU2965192A (en) | 1993-06-10 |
GR3019439T3 (en) | 1996-06-30 |
US5314903A (en) | 1994-05-24 |
NZ245287A (en) | 1995-04-27 |
NO924646L (no) | 1993-06-04 |
AU649899B2 (en) | 1994-06-02 |
NO924646D0 (no) | 1992-12-02 |
DE69208604T2 (de) | 1996-09-05 |
CA2084233A1 (en) | 1993-06-04 |
DK0545845T3 (da) | 1996-08-05 |
EP0545845A1 (en) | 1993-06-09 |
ATE134622T1 (de) | 1996-03-15 |
JPH072796A (ja) | 1995-01-06 |
FI925501A (fi) | 1993-06-04 |
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