ZA928876B - Thiazole derivatives. - Google Patents
Thiazole derivatives.Info
- Publication number
- ZA928876B ZA928876B ZA928876A ZA928876A ZA928876B ZA 928876 B ZA928876 B ZA 928876B ZA 928876 A ZA928876 A ZA 928876A ZA 928876 A ZA928876 A ZA 928876A ZA 928876 B ZA928876 B ZA 928876B
- Authority
- ZA
- South Africa
- Prior art keywords
- suitable substituent
- carbamimidoyl
- hydrogen
- formula
- thiazole derivatives
- Prior art date
Links
- 150000007979 thiazole derivatives Chemical class 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919125970A GB9125970D0 (en) | 1991-12-06 | 1991-12-06 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA928876B true ZA928876B (en) | 1993-07-15 |
Family
ID=10705819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA928876A ZA928876B (en) | 1991-12-06 | 1992-11-17 | Thiazole derivatives. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5532258A (fr) |
EP (1) | EP0545376B1 (fr) |
JP (1) | JP2531329B2 (fr) |
CN (1) | CN1079469A (fr) |
AT (1) | ATE170851T1 (fr) |
AU (1) | AU666893B2 (fr) |
CA (1) | CA2084640A1 (fr) |
DE (1) | DE69226931T2 (fr) |
GB (1) | GB9125970D0 (fr) |
HU (3) | HU9203849D0 (fr) |
IL (1) | IL103826A0 (fr) |
MX (1) | MX9206930A (fr) |
TW (1) | TW211565B (fr) |
ZA (1) | ZA928876B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4427539A1 (de) * | 1994-08-04 | 1996-02-08 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von 2-Cyaniminothiazolidin |
GB9416459D0 (en) * | 1994-08-15 | 1994-10-05 | Fujisawa Pharmaceutical Co | New compounds |
NZ331104A (en) | 1995-12-29 | 2000-03-27 | Boehringer Ingelheim Ca Ltd | Phenyl thiazole derivatives that inhibit herpes replication by inhibiting the herpes helicase primase enzyme complex |
US6288091B1 (en) | 1995-12-29 | 2001-09-11 | Boehringer Ingelheim Ltd. | Antiherpes virus compounds and methods for their preparation and use |
DE19719053A1 (de) * | 1997-05-06 | 1998-11-12 | Bayer Ag | Substituierte Aminothiazole |
US6100282A (en) | 1998-01-02 | 2000-08-08 | Hoffman-La Roche Inc. | Thiazole derivatives |
EP1450901A4 (fr) * | 2001-12-10 | 2005-05-25 | Bristol Myers Squibb Co | Composes de (1-phenyl-2-heteroaryl)ethyl-guanidine utiles en tant qu'inhibiteurs de la f1f0 atp hydrolase mitochondriale |
DE102004008141A1 (de) | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2961923D1 (en) * | 1978-01-18 | 1982-03-11 | Ici Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
CA1233818A (fr) * | 1981-03-09 | 1988-03-08 | David J. Gilman | Derives de la guanidine, inhibiteurs des recepteurs h.sub.2 a l'histamine |
IT1200371B (it) * | 1982-03-24 | 1989-01-18 | Angeli Inst Spa | Guanidino eterociclifenilamidine,processi per la loro preparazione e loro impiego farmaceutico |
US4452985A (en) * | 1983-02-14 | 1984-06-05 | American Home Products Corporation | 2-Guanyl-4-(substituted phenyl) thiazole derivatives |
-
1991
- 1991-12-06 GB GB919125970A patent/GB9125970D0/en active Pending
-
1992
- 1992-11-17 ZA ZA928876A patent/ZA928876B/xx unknown
- 1992-11-20 IL IL103826A patent/IL103826A0/xx unknown
- 1992-11-30 TW TW081109564A patent/TW211565B/zh active
- 1992-12-02 DE DE69226931T patent/DE69226931T2/de not_active Expired - Fee Related
- 1992-12-02 MX MX9206930A patent/MX9206930A/es unknown
- 1992-12-02 JP JP4323052A patent/JP2531329B2/ja not_active Expired - Lifetime
- 1992-12-02 AU AU29837/92A patent/AU666893B2/en not_active Ceased
- 1992-12-02 AT AT92120533T patent/ATE170851T1/de not_active IP Right Cessation
- 1992-12-02 EP EP92120533A patent/EP0545376B1/fr not_active Expired - Lifetime
- 1992-12-04 HU HU9203849A patent/HU9203849D0/hu unknown
- 1992-12-04 CA CA002084640A patent/CA2084640A1/fr not_active Abandoned
- 1992-12-04 HU HU9203849A patent/HUT65776A/hu unknown
- 1992-12-05 CN CN92114939A patent/CN1079469A/zh active Pending
-
1994
- 1994-12-16 US US08/356,967 patent/US5532258A/en not_active Expired - Fee Related
-
1995
- 1995-06-22 HU HU95P/P00396P patent/HU211604A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
US5532258A (en) | 1996-07-02 |
DE69226931T2 (de) | 1999-03-18 |
HU211604A9 (en) | 1995-12-28 |
TW211565B (fr) | 1993-08-21 |
IL103826A0 (en) | 1993-04-04 |
JP2531329B2 (ja) | 1996-09-04 |
MX9206930A (es) | 1993-06-01 |
AU2983792A (en) | 1993-06-10 |
EP0545376B1 (fr) | 1998-09-09 |
HU9203849D0 (en) | 1993-03-29 |
CN1079469A (zh) | 1993-12-15 |
EP0545376A1 (fr) | 1993-06-09 |
JPH06321921A (ja) | 1994-11-22 |
ATE170851T1 (de) | 1998-09-15 |
HUT65776A (en) | 1994-07-28 |
AU666893B2 (en) | 1996-02-29 |
GB9125970D0 (en) | 1992-02-05 |
DE69226931D1 (de) | 1998-10-15 |
CA2084640A1 (fr) | 1993-06-07 |
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