ZA926310B - Pharmaceuticals for the treatment of rejection reactions in organ transplantations - Google Patents

Pharmaceuticals for the treatment of rejection reactions in organ transplantations

Info

Publication number
ZA926310B
ZA926310B ZA926310A ZA926310A ZA926310B ZA 926310 B ZA926310 B ZA 926310B ZA 926310 A ZA926310 A ZA 926310A ZA 926310 A ZA926310 A ZA 926310A ZA 926310 B ZA926310 B ZA 926310B
Authority
ZA
South Africa
Prior art keywords
treatment
pharmaceuticals
rejection reactions
organ transplantations
organ
Prior art date
Application number
ZA926310A
Other languages
English (en)
Inventor
Robert Ryder Bartlett
Ryder Bartlett Robert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA926310B publication Critical patent/ZA926310B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Meat, Egg Or Seafood Products (AREA)
ZA926310A 1991-08-22 1992-08-21 Pharmaceuticals for the treatment of rejection reactions in organ transplantations ZA926310B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4127737A DE4127737A1 (de) 1991-08-22 1991-08-22 Arzneimittel zur behandlung von abstossungsreaktionen bei organverpflanzungen

Publications (1)

Publication Number Publication Date
ZA926310B true ZA926310B (en) 1993-04-28

Family

ID=6438804

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA926310A ZA926310B (en) 1991-08-22 1992-08-21 Pharmaceuticals for the treatment of rejection reactions in organ transplantations

Country Status (18)

Country Link
US (3) US5728721A (fr)
EP (1) EP0529500B1 (fr)
JP (1) JP3285226B2 (fr)
KR (1) KR100253450B1 (fr)
AT (1) ATE113835T1 (fr)
AU (1) AU654031B2 (fr)
CA (1) CA2076555C (fr)
CZ (1) CZ281353B6 (fr)
DE (2) DE4127737A1 (fr)
DK (1) DK0529500T3 (fr)
ES (1) ES2065738T3 (fr)
HU (1) HU219402B (fr)
IL (1) IL102886A (fr)
MX (1) MX9204875A (fr)
RU (1) RU2067862C1 (fr)
SK (1) SK279323B6 (fr)
TW (1) TW210284B (fr)
ZA (1) ZA926310B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133301A (en) * 1991-08-22 2000-10-17 Aventis Pharma Deutschland Gmbh Pharmaceuticals for the treatment of rejection reactions in organ transplantations
DE4127737A1 (de) 1991-08-22 1993-02-25 Hoechst Ag Arzneimittel zur behandlung von abstossungsreaktionen bei organverpflanzungen
US5624946A (en) * 1994-07-05 1997-04-29 Williams; James Use of leflunomide to control and reverse chronic allograft rejection
CA2202904C (fr) * 1994-10-17 2006-12-19 Yukio Amano Composition preventive et remede pour les maladies allergiques de type i
DE19547648A1 (de) 1995-12-20 1997-06-26 Hoechst Ag Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate
DE19610955A1 (de) * 1996-03-20 1997-09-25 Hoechst Ag Kombinationspräparat, enthaltend 5-Methylisoxazol-4-carbonsäure-(4-trifluormethyl)- anilid und N-(4-Trifluormethylphenyl)-2-cyan-3- hydroxycrotonsäureamid
US6011051A (en) * 1996-07-31 2000-01-04 Hoechst Aktiengesellschaft Use of isoxazole and crotonamide derivatives for the modulation of apoptosis
ES2150808T3 (es) * 1997-08-08 2000-12-01 Aventis Pharma Gmbh Forma cristalina de (4-trifluorometil)-anilida de acido 5-metilisoxazol-4-carboxilico.
DE19857009A1 (de) * 1998-12-10 2000-06-15 Aventis Pharma Gmbh Zubereitung mit verbesserter therapeutischer Breite, enthaltend Nukleotidsyntheseinhibitoren
DE19908527C2 (de) * 1999-02-26 2001-08-30 Aventis Pharma Gmbh Verfahren zur Kristallisation von N-(4-Trifluormethylphenyl)-5-methyl-isoxazol-4-carboxamid
FR2802101B1 (fr) 1999-12-10 2003-02-28 Aventis Pharma Sa Association de cymemazine et d'un neuroleptique atypique
DE19960443C2 (de) 1999-12-15 2002-05-08 Aventis Pharma Gmbh Verfahren zur Auffindung von Nukleotidsyntheseinhibitoren mit weniger Nebenwirkungen
CN100415227C (zh) * 2001-10-25 2008-09-03 阿特罗吉尼克斯公司 化合物在制备用于治疗移植排斥的药物中的应用
US20050158371A1 (en) * 2002-02-12 2005-07-21 Sumitomo Pharmaceuticals Co., Ltd. Novel external agent
WO2005011669A1 (fr) * 2003-08-05 2005-02-10 Dainippon Sumitomo Pharma Co., Ltd. Composition medicamenteuse pour administration percutanee
US20060024376A1 (en) * 2004-07-30 2006-02-02 The University Of Chicago Methods and compositions for reducing toxicity associated with leflunomide treatment
DE102005017592A1 (de) * 2005-04-16 2006-10-19 Lindner, Jürgen, Dr. med. Darreichungsformen und Kombinationspräparate von Pyrimidinbiosyntheseinhibitoren zur Erzielung zusätzlicher Wirkungen auf das Immunsystem
CN105272882B (zh) * 2014-07-23 2019-05-31 欣凯医药化工中间体（上海）有限公司 一种环保简便制备泰瑞米特的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2436263C2 (de) 1974-07-27 1983-02-17 Hoechst Ag, 6000 Frankfurt Thiazolidinderivate und Verfahren zu ihrer Herstellung
ES448386A1 (es) 1975-06-05 1978-04-16 Hoechst Ag Procedimiento para la preparacion de anilidas de acido 5-me-til-isoxazol-4-carboxilico.
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2854439A1 (de) 1978-12-16 1980-07-03 Hoechst Ag Ein isoxazolderivat, verfahren zu seiner herstellung, diese verbindung enthaltende mittel und verwendung
GB8320969D0 (en) * 1983-08-03 1983-09-07 Ici Plc Transparent sheet
DE3405727A1 (de) 1984-02-17 1985-08-22 Hoechst Ag, 6230 Frankfurt Isoxazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US5268382A (en) 1985-09-27 1993-12-07 Hoechst Aktiengesellschaft Medicaments to combat autoimmune diseases, in particular systemic lupus erythematosus
US5100899A (en) 1989-06-06 1992-03-31 Roy Calne Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
DE4101324A1 (de) 1991-01-18 1992-07-23 Hoechst Ag Isoxazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US6133301A (en) * 1991-08-22 2000-10-17 Aventis Pharma Deutschland Gmbh Pharmaceuticals for the treatment of rejection reactions in organ transplantations
DE4127737A1 (de) 1991-08-22 1993-02-25 Hoechst Ag Arzneimittel zur behandlung von abstossungsreaktionen bei organverpflanzungen
EP0538783B1 (fr) 1991-10-23 1995-09-27 Hoechst Aktiengesellschaft Dérivés d'amides de l'acide n-phényl-cyano-2-hydroxy-3-crotonique et leur utilisation comme médicaments ayant des propriétés immunomodulants
US5624946A (en) 1994-07-05 1997-04-29 Williams; James Use of leflunomide to control and reverse chronic allograft rejection
US6223209B1 (en) * 1997-09-30 2001-04-24 Ncr Corporation Distributed world wide web servers

Also Published As

Publication number Publication date
US6288098B1 (en) 2001-09-11
CA2076555A1 (fr) 1993-02-23
DE59200773D1 (de) 1994-12-15
AU654031B2 (en) 1994-10-20
US20050080118A1 (en) 2005-04-14
IL102886A0 (en) 1993-01-31
DK0529500T3 (da) 1995-04-18
CZ258292A3 (en) 1993-03-17
MX9204875A (es) 1993-02-01
CA2076555C (fr) 2003-07-29
IL102886A (en) 1996-01-19
JPH05208909A (ja) 1993-08-20
ATE113835T1 (de) 1994-11-15
KR100253450B1 (ko) 2000-07-01
US7402601B2 (en) 2008-07-22
SK279323B6 (sk) 1998-10-07
ES2065738T3 (es) 1995-02-16
DE4127737A1 (de) 1993-02-25
HU219402B (hu) 2001-04-28
TW210284B (fr) 1993-08-01
EP0529500B1 (fr) 1994-11-09
SK258292A3 (en) 1995-09-13
EP0529500A1 (fr) 1993-03-03
AU2124792A (en) 1993-02-25
JP3285226B2 (ja) 2002-05-27
HUT64845A (en) 1994-03-28
CZ281353B6 (cs) 1996-09-11
US5728721A (en) 1998-03-17
RU2067862C1 (ru) 1996-10-20
KR930003915A (ko) 1993-03-22

Similar Documents

Publication Publication Date Title
ZA926310B (en) Pharmaceuticals for the treatment of rejection reactions in organ transplantations
ZA918126B (en) Di(aromatic)compounds and their use in human and veterinary medicine and in cosmetics
KR0140155B1 (en) Fomentation containing ketorolac
GR3025658T3 (en) Contrast media for ultrasonic imaging
HUT68299A (en) Preparations containing (s)-(-)-alfa-etil-2-oxo-1-pirrolidine acetamide for the treatment of anxiety
EP0572635A4 (fr) Nouveaux composes a structure guanidique et composition pharmaceutique les contenant.
IL82147A (en) Substituted oxime-ethers,their preparation and their use for controlling plant growth
AU2721592A (en) N-phenyl-2-cyano-3-hydroxycrotonamide derivatives and their use as pharmaceuticals having an immunomodulatory property
EP0481299A3 (en) N-phenyl-piperidyl-4-amines and drugs containing them
IL89628A0 (en) Guanidinium compounds and their use as fungicides
GR3002486T3 (en) Substituted 5-amino-pyrazoles and fungicides containing them
DE3882381D1 (fr)
ZA796789B (en) Novel 3,4-diaza-bicyclo (4.1.0) hept-2-en-5-ones, their preparation, and therapeutic agents containing these compounds
HU892146D0 (en) Process for the preparation of heteroaromatic compounds containing five-membered ring with nitrogen atom
EP0317913A3 (en) Di(meth)acrylates, process for their preparation and their use
HUT70424A (en) Disulfonyl methane derivatives against parasites and pharmaceutical compositions containing such compounds
PH24258A (en) Substituted quinoxyalyl-imidazolidine-2,4-diones,their use as medicaments and pharmaceutical preparation
GR3006031T3 (fr)
DE59409645D1 (en) Substituierte arylthioalkylthiopyridine
EP0418990A3 (en) 13-bromo and 13,14-dibromo ergoline, their preparation and their use
ZA822193B (en) 5,6-dihydro-11-alkylene-morphanthridin-6-ones,their preparation,and drugs containing these compounds
ES2055155T3 (es) Procedimiento para la obtencion de aciloxiacetidinonas opticamente activas.
PL300522A1 (en) Drugs containing 1,5,6,7-tetrahydro-4h-indasol-4-ones, novel 1,5,6,7-tetrahydro-4h-indasol-4-ones and methods of obtaining sames
PL298827A1 (en) Novel enantiomers derivatives of (s)-2-amino(3,4-dichlorobenzyl) propanol-1