ZA924118B - Isatineoxime derivatives, their preparation and use. - Google Patents
Isatineoxime derivatives, their preparation and use.Info
- Publication number
- ZA924118B ZA924118B ZA924118A ZA924118A ZA924118B ZA 924118 B ZA924118 B ZA 924118B ZA 924118 A ZA924118 A ZA 924118A ZA 924118 A ZA924118 A ZA 924118A ZA 924118 B ZA924118 B ZA 924118B
- Authority
- ZA
- South Africa
- Prior art keywords
- isatineoxime
- derivatives
- preparation
- cyclic
- branched
- Prior art date
Links
- NGXLTYPELAIUHE-UHFFFAOYSA-N 2-(hydroxyamino)indol-3-one Chemical class C1=CC=C2C(=O)C(NO)=NC2=C1 NGXLTYPELAIUHE-UHFFFAOYSA-N 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- OZDAOHVKBFBBMZ-UHFFFAOYSA-N 2-aminopentanedioic acid;hydrate Chemical compound O.OC(=O)C(N)CCC(O)=O OZDAOHVKBFBBMZ-UHFFFAOYSA-N 0.000 abstract 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 108010011562 aspartic acid receptor Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000013922 glutamic acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
- Lubricants (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72747991A | 1991-07-09 | 1991-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA924118B true ZA924118B (en) | 1993-08-03 |
Family
ID=24922831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA924118A ZA924118B (en) | 1991-07-09 | 1992-06-05 | Isatineoxime derivatives, their preparation and use. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0522494B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP3270524B2 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE143659T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU655643B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2073281A1 (cg-RX-API-DMAC10.html) |
| DE (1) | DE69214205T2 (cg-RX-API-DMAC10.html) |
| DK (1) | DK0522494T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2094850T3 (cg-RX-API-DMAC10.html) |
| FI (1) | FI102276B (cg-RX-API-DMAC10.html) |
| GR (1) | GR3021814T3 (cg-RX-API-DMAC10.html) |
| IE (1) | IE921730A1 (cg-RX-API-DMAC10.html) |
| NO (1) | NO178620C (cg-RX-API-DMAC10.html) |
| ZA (1) | ZA924118B (cg-RX-API-DMAC10.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK81593D0 (da) * | 1993-07-07 | 1993-07-07 | Neurosearch As | Nye isatinoximderivater, deres fremstilling og anvendelse |
| AR016384A1 (es) * | 1997-07-30 | 2001-07-04 | Smithkline Beecham Corp | Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta. |
| WO2000071102A2 (en) * | 1999-05-19 | 2000-11-30 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
| US5164404A (en) * | 1991-03-15 | 1992-11-17 | Neurosearch A/S | Hydrazone derivatives and their use |
-
1992
- 1992-05-29 AU AU17268/92A patent/AU655643B2/en not_active Ceased
- 1992-06-05 ZA ZA924118A patent/ZA924118B/xx unknown
- 1992-06-30 FI FI923032A patent/FI102276B/fi active
- 1992-07-01 IE IE173092A patent/IE921730A1/en not_active Application Discontinuation
- 1992-07-07 AT AT92111478T patent/ATE143659T1/de not_active IP Right Cessation
- 1992-07-07 ES ES92111478T patent/ES2094850T3/es not_active Expired - Lifetime
- 1992-07-07 DE DE69214205T patent/DE69214205T2/de not_active Expired - Lifetime
- 1992-07-07 CA CA002073281A patent/CA2073281A1/en not_active Abandoned
- 1992-07-07 DK DK92111478.1T patent/DK0522494T3/da active
- 1992-07-07 JP JP17991692A patent/JP3270524B2/ja not_active Expired - Fee Related
- 1992-07-07 EP EP92111478A patent/EP0522494B1/en not_active Expired - Lifetime
- 1992-07-08 NO NO922686A patent/NO178620C/no unknown
-
1996
- 1996-11-28 GR GR960403205T patent/GR3021814T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO178620C (no) | 1996-05-02 |
| ATE143659T1 (de) | 1996-10-15 |
| DK0522494T3 (cg-RX-API-DMAC10.html) | 1997-03-03 |
| FI102276B1 (fi) | 1998-11-13 |
| FI923032L (fi) | 1993-01-10 |
| JP3270524B2 (ja) | 2002-04-02 |
| EP0522494A1 (en) | 1993-01-13 |
| NO922686D0 (no) | 1992-07-08 |
| DE69214205D1 (de) | 1996-11-07 |
| IE921730A1 (en) | 1993-01-13 |
| AU1726892A (en) | 1993-01-14 |
| NO922686L (no) | 1993-01-11 |
| EP0522494B1 (en) | 1996-10-02 |
| GR3021814T3 (en) | 1997-02-28 |
| FI923032A0 (fi) | 1992-06-30 |
| ES2094850T3 (es) | 1997-02-01 |
| DE69214205T2 (de) | 1997-02-06 |
| JPH05201976A (ja) | 1993-08-10 |
| AU655643B2 (en) | 1995-01-05 |
| CA2073281A1 (en) | 1993-01-10 |
| FI102276B (fi) | 1998-11-13 |
| NO178620B (no) | 1996-01-22 |
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