AU655643B2 - Novel isatineoxime derivatives, their preparation and use - Google Patents

Novel isatineoxime derivatives, their preparation and use

Info

Publication number
AU655643B2
AU655643B2 AU17268/92A AU1726892A AU655643B2 AU 655643 B2 AU655643 B2 AU 655643B2 AU 17268/92 A AU17268/92 A AU 17268/92A AU 1726892 A AU1726892 A AU 1726892A AU 655643 B2 AU655643 B2 AU 655643B2
Authority
AU
Australia
Prior art keywords
compound
cyclic
branched
alkyl
tetrahydrobenz
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU17268/92A
Other languages
English (en)
Other versions
AU1726892A (en
Inventor
Jorgen Drejer
Leif Helth Jensen
Frank Watjen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Publication of AU1726892A publication Critical patent/AU1726892A/en
Application granted granted Critical
Publication of AU655643B2 publication Critical patent/AU655643B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Lubricants (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU17268/92A 1991-07-09 1992-05-29 Novel isatineoxime derivatives, their preparation and use Ceased AU655643B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72747991A 1991-07-09 1991-07-09
US727479 1991-07-09

Publications (2)

Publication Number Publication Date
AU1726892A AU1726892A (en) 1993-01-14
AU655643B2 true AU655643B2 (en) 1995-01-05

Family

ID=24922831

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17268/92A Ceased AU655643B2 (en) 1991-07-09 1992-05-29 Novel isatineoxime derivatives, their preparation and use

Country Status (13)

Country Link
EP (1) EP0522494B1 (cg-RX-API-DMAC10.html)
JP (1) JP3270524B2 (cg-RX-API-DMAC10.html)
AT (1) ATE143659T1 (cg-RX-API-DMAC10.html)
AU (1) AU655643B2 (cg-RX-API-DMAC10.html)
CA (1) CA2073281A1 (cg-RX-API-DMAC10.html)
DE (1) DE69214205T2 (cg-RX-API-DMAC10.html)
DK (1) DK0522494T3 (cg-RX-API-DMAC10.html)
ES (1) ES2094850T3 (cg-RX-API-DMAC10.html)
FI (1) FI102276B (cg-RX-API-DMAC10.html)
GR (1) GR3021814T3 (cg-RX-API-DMAC10.html)
IE (1) IE921730A1 (cg-RX-API-DMAC10.html)
NO (1) NO178620C (cg-RX-API-DMAC10.html)
ZA (1) ZA924118B (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK81593D0 (da) * 1993-07-07 1993-07-07 Neurosearch As Nye isatinoximderivater, deres fremstilling og anvendelse
AR016384A1 (es) * 1997-07-30 2001-07-04 Smithkline Beecham Corp Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta.
WO2000071102A2 (en) * 1999-05-19 2000-11-30 Neurosearch A/S Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1122592A (en) * 1991-03-15 1992-09-17 Neurosearch A/S Hydrazone derivatives, their preparation and use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE69677B1 (en) * 1989-12-11 1996-10-02 Neurosearch As Isatine derivatives their preparation and use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1122592A (en) * 1991-03-15 1992-09-17 Neurosearch A/S Hydrazone derivatives, their preparation and use

Also Published As

Publication number Publication date
NO178620C (no) 1996-05-02
ATE143659T1 (de) 1996-10-15
DK0522494T3 (cg-RX-API-DMAC10.html) 1997-03-03
FI102276B1 (fi) 1998-11-13
FI923032L (fi) 1993-01-10
JP3270524B2 (ja) 2002-04-02
EP0522494A1 (en) 1993-01-13
NO922686D0 (no) 1992-07-08
DE69214205D1 (de) 1996-11-07
IE921730A1 (en) 1993-01-13
AU1726892A (en) 1993-01-14
NO922686L (no) 1993-01-11
EP0522494B1 (en) 1996-10-02
GR3021814T3 (en) 1997-02-28
FI923032A0 (fi) 1992-06-30
ES2094850T3 (es) 1997-02-01
DE69214205T2 (de) 1997-02-06
ZA924118B (en) 1993-08-03
JPH05201976A (ja) 1993-08-10
CA2073281A1 (en) 1993-01-10
FI102276B (fi) 1998-11-13
NO178620B (no) 1996-01-22

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