ZA922441B - Glial mitogenic factors,their preparation and use - Google Patents

Glial mitogenic factors,their preparation and use

Info

Publication number
ZA922441B
ZA922441B ZA922441A ZA922441A ZA922441B ZA 922441 B ZA922441 B ZA 922441B ZA 922441 A ZA922441 A ZA 922441A ZA 922441 A ZA922441 A ZA 922441A ZA 922441 B ZA922441 B ZA 922441B
Authority
ZA
South Africa
Prior art keywords
factors
preparation
mitogenic factors
factor
glial
Prior art date
Application number
ZA922441A
Other languages
English (en)
Inventor
Andrew David John Goodearl
David John Goodearl Andrew
Michael Derek Waterfield
Derek Waterfield Michael
Paul Stroobant
Stroobant Paul
Luisa Dr Minghetti
Minghetti Dr Luisa
Mark Marchionni
Marchionni Mark
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Publication of ZA922441B publication Critical patent/ZA922441B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA922441A 1991-04-10 1992-04-03 Glial mitogenic factors,their preparation and use ZA922441B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919107566A GB9107566D0 (en) 1991-04-10 1991-04-10 Glial mitogenic factors,their preparation and use

Publications (1)

Publication Number Publication Date
ZA922441B true ZA922441B (en) 1992-11-25

Family

ID=10692987

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA922441A ZA922441B (en) 1991-04-10 1992-04-03 Glial mitogenic factors,their preparation and use

Country Status (13)

Country Link
EP (1) EP0579640B1 (ko)
JP (1) JPH06507544A (ko)
KR (1) KR100274305B1 (ko)
AT (1) ATE221083T1 (ko)
AU (2) AU1450992A (ko)
CA (1) CA2108119C (ko)
DE (1) DE69232693T2 (ko)
DK (1) DK0579640T3 (ko)
GB (1) GB9107566D0 (ko)
IE (1) IE921062A1 (ko)
PT (1) PT100344B (ko)
WO (1) WO1992018627A1 (ko)
ZA (1) ZA922441B (ko)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
IL101943A0 (en) * 1991-05-24 1992-12-30 Genentech Inc Structure,production and use of heregulin
US5834229A (en) * 1991-05-24 1998-11-10 Genentech, Inc. Nucleic acids vectors and host cells encoding and expressing heregulin 2-α
US5367060A (en) * 1991-05-24 1994-11-22 Genentech, Inc. Structure, production and use of heregulin
AU693767B2 (en) * 1992-08-10 1998-07-09 Cambridge Neuroscience, Inc. Inhibitors of cell proliferation, their preparation and use
GB9217316D0 (en) * 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use
US5770567A (en) * 1994-11-14 1998-06-23 Genentech, Inc. Sensory and motor neuron derived factor (SMDF)
US6033660A (en) * 1995-05-10 2000-03-07 Genentech, Inc. Method of treating a nervous system injury with cultured schwann cells
US5849585A (en) * 1995-05-10 1998-12-15 Genetech, Inc. Isolating and culturing Schwann cells
US5721139A (en) * 1995-05-10 1998-02-24 Genentech, Inc. Isolating and culturing schwann cells
US5912326A (en) * 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
IL127892A0 (en) 1996-07-12 1999-10-28 Genentech Inc Gamma-heregulin
US6136558A (en) * 1997-02-10 2000-10-24 Genentech, Inc. Heregulin variants
DK0970207T3 (da) 1997-02-10 2009-07-13 Genentech Inc Heregulin-varianter
WO1999031505A1 (en) * 1997-12-15 1999-06-24 Shire Laboratories Inc. Neurotrophic factor assay
US20010023241A1 (en) 1998-02-04 2001-09-20 Sliwkowski Mark X. Use of heregulin as a growth factor
AUPP785098A0 (en) 1998-12-21 1999-01-21 Victor Chang Cardiac Research Institute, The Treatment of heart disease
US6635249B1 (en) 1999-04-23 2003-10-21 Cenes Pharmaceuticals, Inc. Methods for treating congestive heart failure
ITMI20011057A1 (it) * 2001-05-22 2002-11-22 Bracco Imaging Spa Preparazione ed uso di peptidi ciclici e ramificati e loro deriati marcati come agenti terapeutici agonisti o antagonisti della colecistochi
AU2002304965A1 (en) 2002-05-24 2003-12-12 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US7241392B2 (en) 2004-09-09 2007-07-10 Dresser-Rand Company Rotary separator and method
US20070213264A1 (en) 2005-12-02 2007-09-13 Mingdong Zhou Neuregulin variants and methods of screening and using thereof
EP1981525B1 (en) 2005-12-30 2015-01-21 Zensun (Shanghai) Science and Technology Limited Extended release of neuregulin for improved cardiac function
ES2609927T3 (es) 2008-08-15 2017-04-25 Acorda Therapeutics, Inc. Composiciones y métodos para tratamientos durante periodos no agudos después de lesiones neurológicas del SNC
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions and methods for treating heart failure
KR102357275B1 (ko) 2013-05-22 2022-02-03 젠순 (상하이) 사이언스 앤드 테크놀로지 캄파니 리미티드 심부전을 치료하기 위한 뉴레귤린의 연장 방출

Also Published As

Publication number Publication date
GB9107566D0 (en) 1991-05-29
EP0579640B1 (en) 2002-07-24
AU703772B2 (en) 1999-04-01
CA2108119C (en) 2009-06-30
PT100344B (pt) 1999-08-31
DE69232693T2 (de) 2003-04-03
IE921062A1 (en) 1992-10-21
PT100344A (pt) 1993-07-30
EP0579640A1 (en) 1994-01-26
DE69232693D1 (de) 2002-08-29
CA2108119A1 (en) 1992-10-11
WO1992018627A1 (en) 1992-10-29
AU6808396A (en) 1997-01-16
JPH06507544A (ja) 1994-09-01
AU1450992A (en) 1992-11-17
ATE221083T1 (de) 2002-08-15
KR100274305B1 (ko) 2000-12-15
DK0579640T3 (da) 2002-11-11

Similar Documents

Publication Publication Date Title
ZA922441B (en) Glial mitogenic factors,their preparation and use
AU610036B2 (en) Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis inflammation and as immunosuppressants
AU5914590A (en) Muteins of human erythropoietin, the preparation thereof and the use thereof
ZA898233B (en) A cosmetic preparation containing chitosan
EP0444149A4 (en) High molecular weight human angiogenic factors
HK1006278A1 (en) Novel compositions
GR3031354T3 (en) Soluble interferon -receptor, its preparation and use.
FI940186A (fi) 9H-imidatso/1,2-a/bentsimidatsoli-3-asetamidijohdannaisia, niiden valmistus ja niiden käyttö terapiassa
IL101675A (en) Method and pharmaceutical compositions for detecting and localizing tissues having neurokinine 1 receptors
AU1506692A (en) Pharmaceutical compositions
ZA893310B (en) Novel strobilurine derivatives,their preparation and their use
DE58902178D1 (en) Isomere formyl-trimethylbicyclo(2,2,2)oct-7-ene.
IT8820113A0 (it) Derivati peptidici del3_aminodiidrotiofen_2_one, loro preparazione e impiego terapeutico.
AR244972A1 (es) Mejoras en lechos articulados, aplicables a camas ortopedicas, unidades de terapia y otros usos.
GB2270079A (en) CNS Cell differentiation factor,its preparation and use
AU1162592A (en) Low-molecular sulphated poly-beta -2,6-fructofuranosanes and their use in the treatment of degenerative articular ailments
ZA94291B (en) 9H-Imidazo(1,2-a)Benzimidazole-3-acetamide derivatives their preparation and their therapeutic application
FR2707987B1 (fr) Dérivés de 9H-imidazo[1,2-a]benzimidazole-3-acétamide, leur préparation et leur application en thérapeutique .
ZA925003B (en) Aromatic compounds,pharmaceutical compositions containing them and their use in therapy
HUT61658A (en) Baby-cradle and something to sit on standing on smooth soles, swinging by double suspension