GB2270079A - CNS Cell differentiation factor,its preparation and use - Google Patents
CNS Cell differentiation factor,its preparation and useInfo
- Publication number
- GB2270079A GB2270079A GB9319611A GB9319611A GB2270079A GB 2270079 A GB2270079 A GB 2270079A GB 9319611 A GB9319611 A GB 9319611A GB 9319611 A GB9319611 A GB 9319611A GB 2270079 A GB2270079 A GB 2270079A
- Authority
- GB
- United Kingdom
- Prior art keywords
- factor
- preparation
- new
- cell differentiation
- differentiation factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides a new differentiation-promoting factor of molecular weight 20-25 kilodaltons when isolated by SDS-PAGE. The factor causes O-2A progenitor cells to differentiate expressing GFAP. The new factor is a secreted protein. The invention provides therapeutic formulations comprising the new factor, and the use of the factor and those formulations in treating conditions which involve a factor-sensitive or factor-responsive cell type.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9319611A GB2270079A (en) | 1991-03-22 | 1993-09-22 | CNS Cell differentiation factor,its preparation and use |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919106103A GB9106103D0 (en) | 1991-03-22 | 1991-03-22 | Cns cell differentiation factor,its preparation and use |
PCT/GB1992/000500 WO1992016560A1 (en) | 1991-03-22 | 1992-03-20 | Cns cell differentiation factor, its preparation and use |
GB9319611A GB2270079A (en) | 1991-03-22 | 1993-09-22 | CNS Cell differentiation factor,its preparation and use |
Publications (2)
Publication Number | Publication Date |
---|---|
GB9319611D0 GB9319611D0 (en) | 1994-01-05 |
GB2270079A true GB2270079A (en) | 1994-03-02 |
Family
ID=26298622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9319611A Withdrawn GB2270079A (en) | 1991-03-22 | 1993-09-22 | CNS Cell differentiation factor,its preparation and use |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2270079A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002003A1 (en) * | 1989-08-04 | 1991-02-21 | Board Of Regents, The University Of Texas System | Methods and compositions; purified preparation of neural progenitor regulatory factor |
-
1993
- 1993-09-22 GB GB9319611A patent/GB2270079A/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991002003A1 (en) * | 1989-08-04 | 1991-02-21 | Board Of Regents, The University Of Texas System | Methods and compositions; purified preparation of neural progenitor regulatory factor |
Non-Patent Citations (3)
Title |
---|
Nature,vol.335,1 September 1988, pages 70-73 * |
Proc Natl. Acad. Sci. USA, vol.84, February 1987, pages 842-846 * |
Proc. Natl.Acad. Sci.USA,Vol.87,August 1990,pages 6368-6372 * |
Also Published As
Publication number | Publication date |
---|---|
GB9319611D0 (en) | 1994-01-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |