ZA921703B - Acylaminphenol compounds,process for their preparation and pharmaceutical compositions containing them - Google Patents

Acylaminphenol compounds,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA921703B
ZA921703B ZA921703A ZA921703A ZA921703B ZA 921703 B ZA921703 B ZA 921703B ZA 921703 A ZA921703 A ZA 921703A ZA 921703 A ZA921703 A ZA 921703A ZA 921703 B ZA921703 B ZA 921703B
Authority
ZA
South Africa
Prior art keywords
alkyl
represent
different
compounds
pharmaceutical compositions
Prior art date
Application number
ZA921703A
Other languages
English (en)
Inventor
Charles Malen
Malen Charles
Jean-Michel Lacoste
Lacoste Jean-Michel
Jean-Paul Vilaine
Vilaine Jean-Paul
Albert Lenaers
Lenaers Albert
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA921703B publication Critical patent/ZA921703B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/26—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a saturated carbon skeleton containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/27—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA921703A 1991-03-08 1992-03-06 Acylaminphenol compounds,process for their preparation and pharmaceutical compositions containing them ZA921703B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9102800A FR2673625B1 (fr) 1991-03-08 1991-03-08 Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ZA921703B true ZA921703B (en) 1992-11-25

Family

ID=9410501

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921703A ZA921703B (en) 1991-03-08 1992-03-06 Acylaminphenol compounds,process for their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US5254590A (ja)
EP (1) EP0508842B1 (ja)
JP (1) JPH07587B2 (ja)
AT (1) ATE109766T1 (ja)
AU (1) AU643368B2 (ja)
CA (1) CA2062437A1 (ja)
DE (1) DE69200311T2 (ja)
DK (1) DK0508842T3 (ja)
ES (1) ES2062870T3 (ja)
FR (1) FR2673625B1 (ja)
IE (1) IE65579B1 (ja)
NZ (1) NZ241864A (ja)
ZA (1) ZA921703B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3720395B2 (ja) 1994-09-20 2005-11-24 京都薬品工業株式会社 新規ヘテロ環誘導体、その製造方法およびその医薬用途
KR960031425A (ko) * 1995-02-08 1996-09-17 시미주 마사미 다중불포화된 지방산 잔기를 갖는 아닐린 유도체 및 그의 용도
DK0866059T3 (da) * 1995-10-05 2002-03-25 Kyoto Pharma Ind Nye heterocykliske derivater og medicinsk anvendelse deraf
FR2741619B1 (fr) * 1995-11-28 1998-02-13 Pf Medicament Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique
WO1998002412A1 (fr) * 1996-07-12 1998-01-22 Yamanouchi Pharmaceutical Co., Ltd. Derives de propionanilide ou sels de ceux-ci
IT1309421B1 (it) 1998-09-16 2002-01-23 Med Dia S R L Impiego della batocuproina (acido disolfonico) per la valutazione delpotere antiossidante (pao) nei liquidi e soluzioni.
EP1541553B1 (en) * 2002-07-17 2010-06-02 Kyoto Pharmaceutical Industries, Ltd. Indoline compound and medicinal use thereof
US7566808B2 (en) * 2004-02-17 2009-07-28 President And Fellows Of Harvard College Management of ophthalmologic disorders, including macular degeneration
KR20070032795A (ko) * 2004-06-21 2007-03-22 허치슨 메디파르마 엔터프라이즈 리미티드 항암 화학요법
WO2006009840A1 (en) * 2004-06-21 2006-01-26 Hutchison Medipharma Enterprises Limited Benzoquinone compounds as a anti-cancer agents
WO2007127908A2 (en) * 2006-04-28 2007-11-08 Hutchison Medipharma Enterprises Limited Dihydrobenzoquinone compounds
FR2973374B1 (fr) * 2011-04-04 2013-08-23 Pf Medicament Nouveaux alkylthioethers, leur preparation et leur application en therapeutique
WO2014080306A2 (en) * 2012-11-20 2014-05-30 Mahesh Kandula Compositions and methods for the treatment of cardiovascular diseases
WO2016032345A1 (en) 2014-08-26 2016-03-03 Ibex And Kando Solutions Limited Productivity enhancement for band saw

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2852540A (en) * 1954-08-09 1958-09-16 Exxon Research Engineering Co Oil soluble alkali and alkaline earth metal salts of p-acylamino phenols
US3621043A (en) * 1963-02-06 1971-11-16 Sumitomo Chemical Co N-substituted octadecadienoic acid amides as cholesterol lowering agents
NL130295C (ja) * 1964-04-28
US3479377A (en) * 1965-12-20 1969-11-18 Ashland Oil Inc Hydroxy phenyl fatty amides and polymers thereof,their preparation and use
NL150334B (nl) * 1966-10-04 1976-08-16 Sumito Chemical Werkwijze voor het bereiden van een geneesmiddel met cholesterolspiegel-verlagende werking, alsmede gevormd geneesmiddel.
US3784577A (en) * 1971-10-26 1974-01-08 Sumitomo Chemical Co Fatty acid amide derivatives
US4751026A (en) * 1986-03-24 1988-06-14 Warner-Lambert Company Substituted anilides of oleic, linoleic, or linolenic acid as inhibitors of acyl-coa:cholesterol acyltransferase
US4716175A (en) * 1987-02-24 1987-12-29 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase
AU7745991A (en) * 1990-04-11 1991-10-30 Warner-Lambert Company Amide ester acat inhibitors
JPH0454119A (ja) * 1990-06-20 1992-02-21 Tanabe Seiyaku Co Ltd ５―リポキシゲナーゼ阻害剤

Also Published As

Publication number Publication date
JPH04327564A (ja) 1992-11-17
US5254590A (en) 1993-10-19
DE69200311D1 (de) 1994-09-15
IE65579B1 (en) 1995-11-01
FR2673625B1 (fr) 1993-05-07
IE920719A1 (en) 1992-09-09
DK0508842T3 (da) 1995-01-02
ES2062870T3 (es) 1994-12-16
EP0508842B1 (fr) 1994-08-10
FR2673625A1 (fr) 1992-09-11
AU1146992A (en) 1992-09-10
CA2062437A1 (fr) 1992-09-09
AU643368B2 (en) 1993-11-11
JPH07587B2 (ja) 1995-01-11
EP0508842A1 (fr) 1992-10-14
DE69200311T2 (de) 1995-03-30
NZ241864A (en) 1993-10-26
ATE109766T1 (de) 1994-08-15

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