ZA921615B - Imidazoacridines and their antineoplastic use - Google Patents

Imidazoacridines and their antineoplastic use

Info

Publication number
ZA921615B
ZA921615B ZA921615A ZA921615A ZA921615B ZA 921615 B ZA921615 B ZA 921615B ZA 921615 A ZA921615 A ZA 921615A ZA 921615 A ZA921615 A ZA 921615A ZA 921615 B ZA921615 B ZA 921615B
Authority
ZA
South Africa
Prior art keywords
alkyl
imidazoacridines
antineoplastic
hydrogen
antineoplastic use
Prior art date
Application number
ZA921615A
Other languages
English (en)
Inventor
Wieslaw Marek Cholody
Marek Cholody Wieslaw
Jerzy Kazimierz Konopa
Kazimierz Konopa Jerzy
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group filed Critical British Tech Group
Publication of ZA921615B publication Critical patent/ZA921615B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA921615A 1991-03-05 1992-03-04 Imidazoacridines and their antineoplastic use ZA921615B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919104548A GB9104548D0 (en) 1991-03-05 1991-03-05 Antineoplastic modified imidazoacridines

Publications (1)

Publication Number Publication Date
ZA921615B true ZA921615B (en) 1992-11-25

Family

ID=10690967

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921615A ZA921615B (en) 1991-03-05 1992-03-04 Imidazoacridines and their antineoplastic use

Country Status (17)

Country Link
US (1) US5231100A (pl)
EP (2) EP0579614B1 (pl)
JP (1) JP3176062B2 (pl)
AT (1) ATE153664T1 (pl)
AU (1) AU654700B2 (pl)
CA (1) CA2051356C (pl)
DE (1) DE69220048T2 (pl)
DK (1) DK0579614T3 (pl)
ES (1) ES2103931T3 (pl)
GB (2) GB9104548D0 (pl)
GR (1) GR3024485T3 (pl)
IE (1) IE66260B1 (pl)
IL (1) IL101139A (pl)
NO (1) NO300175B1 (pl)
PL (1) PL167640B1 (pl)
WO (1) WO1992015583A1 (pl)
ZA (1) ZA921615B (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0604181A1 (en) * 1992-12-21 1994-06-29 Eli Lilly And Company Antitumor compositions and method of treatment
US5508289A (en) * 1994-03-14 1996-04-16 The United States America As Represented By The Department Of Health And Human Services Bis-acridone chemotherapeutic derivatives
AU7456396A (en) * 1995-11-02 1997-05-22 Warner-Lambert Company Inhibition of amyloidosis by 9-acridinones
EP0892801B1 (en) * 1996-04-12 2002-01-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Acridone-derived compounds useful as antineoplastic and antiretroviral agents
GB2317888A (en) * 1996-10-07 1998-04-08 Marek Tadeusz Konieczny Acridone derivatives and preparation of 8-hydroxy-imidazoacridinone derivatives
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale
JP2003525940A (ja) * 2000-03-07 2003-09-02 アメリカ合衆国 抗−腫瘍活性を有する、１，８−ナフタルイミドイミダゾ〔４，５，１−ｄｅ〕アクリドン類
EP1871367A2 (en) * 2005-01-28 2008-01-02 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory and demyelinating diseases
WO2007092436A2 (en) * 2006-02-08 2007-08-16 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory disorders, demyelinating disorders and cancers
WO2007143096A2 (en) * 2006-06-02 2007-12-13 Xanthus Pharmaceuticals, Inc. Compounds for treating cancers
WO2008016660A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. Imidazoacridine compounds for treating leukemias
WO2008016700A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. N-oxide compounds for therapeutics uses
US20100016300A1 (en) * 2006-08-02 2010-01-21 Ajami Alfred M Imidazoacridine Compounds for Treating FLT3-Mediated Disorders
US20080118576A1 (en) * 2006-08-28 2008-05-22 Dan Theodorescu Prediction of an agent's or agents' activity across different cells and tissue types
US8470844B2 (en) * 2008-09-11 2013-06-25 Technion Research & Development Foundation Limited Imidazoacridinone derivative compounds and methods for their use
EP3070078B1 (en) * 2015-03-20 2017-10-04 Politechnika Gdanska Asymmetric bis-acridines with antitumor activity and use thereof
CN108135863B (zh) * 2015-04-27 2021-07-27 特拉维夫医疗中心医学研究基础设施和保健服务基金会 用于治疗炎性和过度增殖性病况的egr1靶向分子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1037377A (en) * 1964-09-02 1966-07-27 Mitsubishi Chem Ind Naphthoylene-arylimidazole disperse dyestuffs
US4626540A (en) * 1983-11-08 1986-12-02 Warner-Lambert Company Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
JP2795460B2 (ja) * 1988-06-20 1998-09-10 協和醗酵工業株式会社 ピラゾロアクリドン誘導体

Also Published As

Publication number Publication date
AU1274392A (en) 1992-10-06
ES2103931T3 (es) 1997-10-01
IL101139A0 (en) 1992-11-15
NO933147L (no) 1993-09-03
ATE153664T1 (de) 1997-06-15
DK0579614T3 (da) 1997-12-15
CA2051356C (en) 2002-01-08
EP0579614A1 (en) 1994-01-26
NO933147D0 (no) 1993-09-03
GB2253396A (en) 1992-09-09
GR3024485T3 (en) 1997-11-28
DE69220048D1 (de) 1997-07-03
EP0502668A1 (en) 1992-09-09
CA2051356A1 (en) 1992-09-06
NO300175B1 (no) 1997-04-21
GB9204315D0 (en) 1992-04-08
WO1992015583A1 (en) 1992-09-17
PL167640B1 (pl) 1995-10-31
JP3176062B2 (ja) 2001-06-11
EP0579614B1 (en) 1997-05-28
IE920677A1 (en) 1992-09-09
AU654700B2 (en) 1994-11-17
IL101139A (en) 1995-01-24
GB2253396B (en) 1994-08-10
GB9104548D0 (en) 1991-04-17
IE66260B1 (en) 1995-12-27
US5231100A (en) 1993-07-27
DE69220048T2 (de) 1997-10-02
JPH06508102A (ja) 1994-09-14

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