ZA921615B - Imidazoacridines and their antineoplastic use - Google Patents

Imidazoacridines and their antineoplastic use

Info

Publication number
ZA921615B
ZA921615B ZA921615A ZA921615A ZA921615B ZA 921615 B ZA921615 B ZA 921615B ZA 921615 A ZA921615 A ZA 921615A ZA 921615 A ZA921615 A ZA 921615A ZA 921615 B ZA921615 B ZA 921615B
Authority
ZA
South Africa
Prior art keywords
alkyl
imidazoacridines
antineoplastic
hydrogen
antineoplastic use
Prior art date
Application number
ZA921615A
Other languages
English (en)
Inventor
Wieslaw Marek Cholody
Marek Cholody Wieslaw
Jerzy Kazimierz Konopa
Kazimierz Konopa Jerzy
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group filed Critical British Tech Group
Publication of ZA921615B publication Critical patent/ZA921615B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA921615A 1991-03-05 1992-03-04 Imidazoacridines and their antineoplastic use ZA921615B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919104548A GB9104548D0 (en) 1991-03-05 1991-03-05 Antineoplastic modified imidazoacridines

Publications (1)

Publication Number Publication Date
ZA921615B true ZA921615B (en) 1992-11-25

Family

ID=10690967

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921615A ZA921615B (en) 1991-03-05 1992-03-04 Imidazoacridines and their antineoplastic use

Country Status (17)

Country Link
US (1) US5231100A (xx)
EP (2) EP0502668A1 (xx)
JP (1) JP3176062B2 (xx)
AT (1) ATE153664T1 (xx)
AU (1) AU654700B2 (xx)
CA (1) CA2051356C (xx)
DE (1) DE69220048T2 (xx)
DK (1) DK0579614T3 (xx)
ES (1) ES2103931T3 (xx)
GB (2) GB9104548D0 (xx)
GR (1) GR3024485T3 (xx)
IE (1) IE66260B1 (xx)
IL (1) IL101139A (xx)
NO (1) NO300175B1 (xx)
PL (1) PL167640B1 (xx)
WO (1) WO1992015583A1 (xx)
ZA (1) ZA921615B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0604181A1 (en) * 1992-12-21 1994-06-29 Eli Lilly And Company Antitumor compositions and method of treatment
US5508289A (en) * 1994-03-14 1996-04-16 The United States America As Represented By The Department Of Health And Human Services Bis-acridone chemotherapeutic derivatives
US5972956A (en) * 1995-11-02 1999-10-26 Warner-Lambert Company Inhibition of amyloidosis by 9-acridinones
ATE211471T1 (de) 1996-04-12 2002-01-15 Us Gov Health & Human Serv Acridonderivate als antineoplastische-und antiretrovirale mittel
GB2317888A (en) 1996-10-07 1998-04-08 Marek Tadeusz Konieczny Acridone derivatives and preparation of 8-hydroxy-imidazoacridinone derivatives
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale
WO2001066545A2 (en) * 2000-03-07 2001-09-13 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-de]ACRIDONES WITH ANTI-TUMOR ACTIVITY
AU2006209225A1 (en) * 2005-01-28 2006-08-03 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory and demyelinating diseases
WO2007092436A2 (en) * 2006-02-08 2007-08-16 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory disorders, demyelinating disorders and cancers
WO2007143096A2 (en) * 2006-06-02 2007-12-13 Xanthus Pharmaceuticals, Inc. Compounds for treating cancers
WO2008016660A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. Imidazoacridine compounds for treating leukemias
US20100016300A1 (en) * 2006-08-02 2010-01-21 Ajami Alfred M Imidazoacridine Compounds for Treating FLT3-Mediated Disorders
WO2008016700A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. N-oxide compounds for therapeutics uses
US20080118576A1 (en) * 2006-08-28 2008-05-22 Dan Theodorescu Prediction of an agent's or agents' activity across different cells and tissue types
US8470844B2 (en) * 2008-09-11 2013-06-25 Technion Research & Development Foundation Limited Imidazoacridinone derivative compounds and methods for their use
PL3070078T3 (pl) * 2015-03-20 2018-02-28 Politechnika Gdańska Niesymetryczne bisakrydyny o działaniu przeciwnowotworowym i ich zastosowania
US20180289728A1 (en) * 2015-04-27 2018-10-11 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Egr1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1037377A (en) * 1964-09-02 1966-07-27 Mitsubishi Chem Ind Naphthoylene-arylimidazole disperse dyestuffs
US4626540A (en) * 1983-11-08 1986-12-02 Warner-Lambert Company Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
JP2795460B2 (ja) * 1988-06-20 1998-09-10 協和醗酵工業株式会社 ピラゾロアクリドン誘導体

Also Published As

Publication number Publication date
GB9104548D0 (en) 1991-04-17
WO1992015583A1 (en) 1992-09-17
GB9204315D0 (en) 1992-04-08
CA2051356A1 (en) 1992-09-06
JP3176062B2 (ja) 2001-06-11
IE920677A1 (en) 1992-09-09
IE66260B1 (en) 1995-12-27
GB2253396B (en) 1994-08-10
EP0579614B1 (en) 1997-05-28
DK0579614T3 (da) 1997-12-15
DE69220048D1 (de) 1997-07-03
PL167640B1 (pl) 1995-10-31
EP0502668A1 (en) 1992-09-09
NO933147D0 (no) 1993-09-03
ATE153664T1 (de) 1997-06-15
CA2051356C (en) 2002-01-08
IL101139A (en) 1995-01-24
EP0579614A1 (en) 1994-01-26
US5231100A (en) 1993-07-27
AU654700B2 (en) 1994-11-17
GR3024485T3 (en) 1997-11-28
ES2103931T3 (es) 1997-10-01
DE69220048T2 (de) 1997-10-02
JPH06508102A (ja) 1994-09-14
AU1274392A (en) 1992-10-06
NO933147L (no) 1993-09-03
NO300175B1 (no) 1997-04-21
IL101139A0 (en) 1992-11-15
GB2253396A (en) 1992-09-09

Similar Documents

Publication Publication Date Title
GB2253396B (en) Imidazoacridines and their antineoplastic use
GR3029603T3 (en) Cytotoxic stilbene derivatives and pharmaceutical composition containing them.
DK0379979T3 (xx)
TW274541B (xx)
IL110151A0 (en) Amide and urea derivatives and pharmaceutical compositions containing the same
ES2103027T3 (es) Derivados de tienopiridina y composiciones farmaceuticas que los contienen.
NZ232283A (en) Substituted imidazo(1,2-b)pyridazine derivatives; pharmaceutical compositions and preparatory processes
MX9201020A (es) 6,9-bis(amino-substituidas)benzo[g]isoquinolin-5,10-dionas.
EP0255164A3 (en) Use of a thioester for preparing pharmaceutical compositions for the treatment of ischemia and reperfusion syndromes
AU4811396A (en) Substituted benzothienylpiperazines their use as medicaments, and processes for their preparation
GB8805642D0 (en) New cephem compounds & processes for preparation thereof
AU1774188A (en) New tripeptide derivatives having a polycyclic nitrogenous structure, process of the preparation thereof and pharmaceutical compositions containing them
PH31171A (en) Aminobenzonic acid derivatives useful for treatinggastrointestinal conditions.
DE69429753D1 (de) Anitbiotisch wirksame Cephalosporine und Verfahren zu ihrer Herstellung
HU9502627D0 (en) Antitumor compositions and methods of treatment
NO174670C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 1H-pyrido(4,3-b)indol-1-on-derivater
ZA905407B (en) Pyrrolo(2,1-b)thiozle derivatives
AU586089B2 (en) Phosphodiesterace type 111 inhibitors having a thiadiazinone ring as part of a tricyclic structure