ATE153664T1 - Imidazoacridine und ihre antineoplastische anwendung - Google Patents

Imidazoacridine und ihre antineoplastische anwendung

Info

Publication number
ATE153664T1
ATE153664T1 AT92905201T AT92905201T ATE153664T1 AT E153664 T1 ATE153664 T1 AT E153664T1 AT 92905201 T AT92905201 T AT 92905201T AT 92905201 T AT92905201 T AT 92905201T AT E153664 T1 ATE153664 T1 AT E153664T1
Authority
AT
Austria
Prior art keywords
alkyl
imidazoacridine
antineoplastic application
antineoplastic
hydrogen
Prior art date
Application number
AT92905201T
Other languages
English (en)
Inventor
Wieslaw Marek Cholody
Jerzy Kazimierz Konopa
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group filed Critical British Tech Group
Application granted granted Critical
Publication of ATE153664T1 publication Critical patent/ATE153664T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT92905201T 1991-03-05 1992-02-28 Imidazoacridine und ihre antineoplastische anwendung ATE153664T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919104548A GB9104548D0 (en) 1991-03-05 1991-03-05 Antineoplastic modified imidazoacridines

Publications (1)

Publication Number Publication Date
ATE153664T1 true ATE153664T1 (de) 1997-06-15

Family

ID=10690967

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92905201T ATE153664T1 (de) 1991-03-05 1992-02-28 Imidazoacridine und ihre antineoplastische anwendung

Country Status (17)

Country Link
US (1) US5231100A (de)
EP (2) EP0502668A1 (de)
JP (1) JP3176062B2 (de)
AT (1) ATE153664T1 (de)
AU (1) AU654700B2 (de)
CA (1) CA2051356C (de)
DE (1) DE69220048T2 (de)
DK (1) DK0579614T3 (de)
ES (1) ES2103931T3 (de)
GB (2) GB9104548D0 (de)
GR (1) GR3024485T3 (de)
IE (1) IE66260B1 (de)
IL (1) IL101139A (de)
NO (1) NO300175B1 (de)
PL (1) PL167640B1 (de)
WO (1) WO1992015583A1 (de)
ZA (1) ZA921615B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0604181A1 (de) * 1992-12-21 1994-06-29 Eli Lilly And Company Antitumorpräparate und Behandlungsmethoden
US5508289A (en) * 1994-03-14 1996-04-16 The United States America As Represented By The Department Of Health And Human Services Bis-acridone chemotherapeutic derivatives
AU7456396A (en) * 1995-11-02 1997-05-22 Warner-Lambert Company Inhibition of amyloidosis by 9-acridinones
US6187775B1 (en) * 1996-04-12 2001-02-13 The United States Of America As Represented By The Department Of Health And Human Services Acridone-derived compounds useful as antineoplastic and antiretroviral agents
GB2317888A (en) * 1996-10-07 1998-04-08 Marek Tadeusz Konieczny Acridone derivatives and preparation of 8-hydroxy-imidazoacridinone derivatives
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale
EP1265898B1 (de) 2000-03-07 2003-09-24 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 1,8-naphthalimid imidazo[4,5,1-de]acridone mit antitumorwirkung
JP2008528616A (ja) * 2005-01-28 2008-07-31 ザンサス ファーマシューティカルズ， インコーポレイテッド 炎症性疾患および脱髄性疾患を処置するための化合物
WO2007092436A2 (en) * 2006-02-08 2007-08-16 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory disorders, demyelinating disorders and cancers
WO2007143096A2 (en) * 2006-06-02 2007-12-13 Xanthus Pharmaceuticals, Inc. Compounds for treating cancers
WO2008016660A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. Imidazoacridine compounds for treating leukemias
US20100016300A1 (en) * 2006-08-02 2010-01-21 Ajami Alfred M Imidazoacridine Compounds for Treating FLT3-Mediated Disorders
WO2008016700A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. N-oxide compounds for therapeutics uses
US20080118576A1 (en) * 2006-08-28 2008-05-22 Dan Theodorescu Prediction of an agent's or agents' activity across different cells and tissue types
US8470844B2 (en) * 2008-09-11 2013-06-25 Technion Research & Development Foundation Limited Imidazoacridinone derivative compounds and methods for their use
EP3070078B1 (de) * 2015-03-20 2017-10-04 Politechnika Gdanska Unsymmetrische bisacridine und ihre verwendung zur behandlung von tumoren
ES2951653T3 (es) 2015-04-27 2023-10-24 Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct Moléculas dirigidas a EGR1 para el tratamiento de afecciones inflamatorias e hiperproliferativas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1037377A (en) * 1964-09-02 1966-07-27 Mitsubishi Chem Ind Naphthoylene-arylimidazole disperse dyestuffs
US4626540A (en) * 1983-11-08 1986-12-02 Warner-Lambert Company Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
JP2795460B2 (ja) * 1988-06-20 1998-09-10 協和醗酵工業株式会社 ピラゾロアクリドン誘導体

Also Published As

Publication number Publication date
WO1992015583A1 (en) 1992-09-17
CA2051356C (en) 2002-01-08
DE69220048T2 (de) 1997-10-02
NO300175B1 (no) 1997-04-21
GB2253396B (en) 1994-08-10
EP0579614B1 (de) 1997-05-28
EP0579614A1 (de) 1994-01-26
IL101139A (en) 1995-01-24
IL101139A0 (en) 1992-11-15
JP3176062B2 (ja) 2001-06-11
DK0579614T3 (da) 1997-12-15
NO933147L (no) 1993-09-03
GB9204315D0 (en) 1992-04-08
GR3024485T3 (en) 1997-11-28
ZA921615B (en) 1992-11-25
IE66260B1 (en) 1995-12-27
EP0502668A1 (de) 1992-09-09
NO933147D0 (no) 1993-09-03
ES2103931T3 (es) 1997-10-01
AU654700B2 (en) 1994-11-17
PL167640B1 (pl) 1995-10-31
US5231100A (en) 1993-07-27
GB9104548D0 (en) 1991-04-17
AU1274392A (en) 1992-10-06
CA2051356A1 (en) 1992-09-06
GB2253396A (en) 1992-09-09
IE920677A1 (en) 1992-09-09
JPH06508102A (ja) 1994-09-14
DE69220048D1 (de) 1997-07-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee