ZA919438B - Use of xanthines for the preparation of a medicament having immuno supressing activity - Google Patents

Use of xanthines for the preparation of a medicament having immuno supressing activity

Info

Publication number
ZA919438B
ZA919438B ZA919438A ZA919438A ZA919438B ZA 919438 B ZA919438 B ZA 919438B ZA 919438 A ZA919438 A ZA 919438A ZA 919438 A ZA919438 A ZA 919438A ZA 919438 B ZA919438 B ZA 919438B
Authority
ZA
South Africa
Prior art keywords
supressing
xanthines
immuno
medicament
activity
Prior art date
Application number
ZA919438A
Other languages
English (en)
Inventor
James A Bianco
A Bianco James
Jack W Singer
W Singer Jack
William J Novick Jr
J Novick William Jr
Original Assignee
Hoechst Roussel Pharma
Hutchinson Fred Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma, Hutchinson Fred Cancer Res filed Critical Hoechst Roussel Pharma
Publication of ZA919438B publication Critical patent/ZA919438B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA919438A 1990-11-30 1991-11-29 Use of xanthines for the preparation of a medicament having immuno supressing activity ZA919438B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62048090A 1990-11-30 1990-11-30

Publications (1)

Publication Number Publication Date
ZA919438B true ZA919438B (en) 1992-08-26

Family

ID=24486121

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919438A ZA919438B (en) 1990-11-30 1991-11-29 Use of xanthines for the preparation of a medicament having immuno supressing activity

Country Status (10)

Country Link
EP (1) EP0490181A1 (https=)
JP (1) JPH06100450A (https=)
KR (1) KR920009399A (https=)
CA (1) CA2056723A1 (https=)
HU (1) HUT59825A (https=)
IE (1) IE914163A1 (https=)
IL (1) IL100195A0 (https=)
PT (1) PT99659A (https=)
TW (1) TW205507B (https=)
ZA (1) ZA919438B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0573617A1 (en) * 1991-05-24 1993-12-15 Fred Hutchinson Cancer Research Center Modulation of cellular response to external stimuli
DE4411660A1 (de) * 1994-04-05 1995-10-12 Hoechst Ag Verwendung von Xanthinderivaten zur Reduktion der pathologischen Hyperreagibilität eosinophiler Granulozyten, neue Xanthinverbindungen und Verfahren zu deren Herstellung
DE4430127A1 (de) * 1994-08-25 1996-03-14 Hoechst Ag Kombinationspräparat, enthaltend Cyclosporin A oder FK506 und ein Xanthinderivat
DE4430128A1 (de) 1994-08-25 1996-02-29 Hoechst Ag Kombinationspräparat mit immunsuppressiven, kardiovaskulären und cerebralen Wirkungen
US6323201B1 (en) 1994-12-29 2001-11-27 The Regents Of The University Of California Compounds for inhibition of ceramide-mediated signal transduction
ATE234099T1 (de) * 1998-04-24 2003-03-15 Leuven K U Res & Dev Immununterdrückende effekte von 8 substituierten xanthinderivaten
US6930101B1 (en) 1999-05-17 2005-08-16 The Regents Of The University Of California Thiazolopyrimidines useful as TNFα inhibitors
US7253176B1 (en) 2000-05-04 2007-08-07 K.U. Leuven Research & Development Immunosuppressive effects of 8-substituted xanthine derivatives
CN101998957B (zh) 2008-02-29 2013-06-05 康塞特医药品有限公司 取代的黄嘌呤衍生物
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
IN2012DN01642A (https=) 2009-09-02 2015-06-05 Concert Pharmaceuticals Inc
WO2012031138A2 (en) 2010-09-01 2012-03-08 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione
WO2013013052A1 (en) 2011-07-19 2013-01-24 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
EA201491878A8 (ru) 2012-04-13 2015-02-27 Концерт Фармасьютикалс, Инк. Замещенные ксантиновые производные
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione
US9549869B2 (en) 2012-06-29 2017-01-24 Hill-Rom Canado Respiratory Ltd. Wearable thorax percussion device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063827B1 (fr) * 1980-05-02 1985-08-14 Societe Des Produits Nestle S.A. 1-Isopropyl- et 1-isobutyl-3,7-diméthylxanthine comme médicaments
US4965271A (en) * 1986-12-31 1990-10-23 Hoechst Roussel Pharmaceuticals, Inc. Method of inhibiting the activity of leukocyte derived cytokines
IL100536A (en) * 1986-12-31 1994-05-30 Hoechst Roussel Pharma Pharmaceutical preparations containing a history of xanthine Stopping an immune response and relieving adverse conditions resulting from intracellular intervention in an immune response
GB8918297D0 (en) * 1989-08-10 1989-09-20 Beecham Group Plc Novel treatment

Also Published As

Publication number Publication date
JPH06100450A (ja) 1994-04-12
EP0490181A1 (en) 1992-06-17
KR920009399A (ko) 1992-06-25
IL100195A0 (en) 1992-08-18
HUT59825A (en) 1992-07-28
TW205507B (https=) 1993-05-11
IE914163A1 (en) 1992-06-03
PT99659A (pt) 1992-10-30
HU913721D0 (en) 1992-02-28
CA2056723A1 (en) 1992-05-31

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