ZA916420B - 19-nor steroids having a carbonated chain containing an amide function in position 11 beta,their preparation,their use as medicaments and the pharmaceutical compositions containing them - Google Patents
19-nor steroids having a carbonated chain containing an amide function in position 11 beta,their preparation,their use as medicaments and the pharmaceutical compositions containing themInfo
- Publication number
- ZA916420B ZA916420B ZA916420A ZA916420A ZA916420B ZA 916420 B ZA916420 B ZA 916420B ZA 916420 A ZA916420 A ZA 916420A ZA 916420 A ZA916420 A ZA 916420A ZA 916420 B ZA916420 B ZA 916420B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrogen
- preparation
- pharmaceutical compositions
- steroids
- medicaments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9010323A FR2665901B2 (fr) | 1989-02-24 | 1990-08-14 | Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments. |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA916420B true ZA916420B (en) | 1992-10-28 |
Family
ID=9399655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA916420A ZA916420B (en) | 1990-08-14 | 1991-08-14 | 19-nor steroids having a carbonated chain containing an amide function in position 11 beta,their preparation,their use as medicaments and the pharmaceutical compositions containing them |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0471612B1 (de) |
JP (1) | JP3073803B2 (de) |
KR (1) | KR920004408A (de) |
AT (1) | ATE162797T1 (de) |
AU (1) | AU644671B2 (de) |
CA (1) | CA2049102A1 (de) |
DE (1) | DE69128820T2 (de) |
DK (1) | DK0471612T3 (de) |
ES (1) | ES2112268T3 (de) |
GR (1) | GR3026315T3 (de) |
HU (1) | HUT59416A (de) |
IE (1) | IE912863A1 (de) |
MX (1) | MX9100647A (de) |
PT (1) | PT98681B (de) |
ZA (1) | ZA916420B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2685332A1 (fr) * | 1991-12-20 | 1993-06-25 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments. |
JP3398748B2 (ja) * | 1993-01-21 | 2003-04-21 | メレルダウファーマスーティカルズ インコーポレイテッド | 多剤耐性腫瘍剤として有用なジアリールアルキルピペリジン類 |
FR2706454B1 (fr) * | 1993-06-17 | 1995-09-15 | Roussel Uclaf | Nouveaux 19-Nor stéroïdes, procédé et intermédiaires de préparation, application comme médicaments et compositions pharmaceutiques les contenant. |
US5670521A (en) * | 1994-08-05 | 1997-09-23 | Merrell Pharmaceuticals Inc. | Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives |
DE19724187A1 (de) * | 1997-06-02 | 1998-12-03 | Schering Ag | 11beta-Arylsubstituierte 14,17-Ethanoestratriene, Verfahren zur Herstellung dieser Verbindungen, sowie ihre Verwendung zur Herstellung von Arzneimitteln |
US6054446A (en) * | 1997-12-24 | 2000-04-25 | Sri International | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
AU6228299A (en) * | 1998-10-29 | 2000-05-22 | Teikoku Hormone Mfg. Co., Ltd. | 2-substituted-d-homooxasteroid derivatives |
DE19929715A1 (de) * | 1999-06-24 | 2000-12-28 | Schering Ag | 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln |
DE102009034526A1 (de) * | 2009-07-21 | 2011-02-10 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
US9394287B2 (en) | 2010-11-05 | 2016-07-19 | Senomyx, Inc. | Compounds useful as modulators of TRPM8 |
WO2017058594A1 (en) | 2015-10-01 | 2017-04-06 | Senomyx, Inc. | Compounds useful as modulators of trpm8 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2235949B1 (de) * | 1973-06-18 | 1978-03-17 | Roussel Uclaf | |
AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
DE3621024C2 (de) * | 1986-06-20 | 1999-10-28 | Schering Ag | 11beta-Phenylestradiene, deren Herstellung und diese enthaltende pharmazeutische Präparate |
FR2620707B1 (fr) * | 1987-09-18 | 1989-12-08 | Roussel Uclaf | Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
-
1991
- 1991-08-09 AT AT91402214T patent/ATE162797T1/de not_active IP Right Cessation
- 1991-08-09 EP EP91402214A patent/EP0471612B1/de not_active Expired - Lifetime
- 1991-08-09 DK DK91402214T patent/DK0471612T3/da active
- 1991-08-09 ES ES91402214T patent/ES2112268T3/es not_active Expired - Lifetime
- 1991-08-09 DE DE69128820T patent/DE69128820T2/de not_active Expired - Fee Related
- 1991-08-13 KR KR1019910013914A patent/KR920004408A/ko not_active Application Discontinuation
- 1991-08-13 JP JP03226410A patent/JP3073803B2/ja not_active Expired - Fee Related
- 1991-08-13 CA CA002049102A patent/CA2049102A1/fr not_active Abandoned
- 1991-08-13 MX MX9100647A patent/MX9100647A/es unknown
- 1991-08-13 IE IE286391A patent/IE912863A1/en not_active IP Right Cessation
- 1991-08-13 HU HU912690A patent/HUT59416A/hu unknown
- 1991-08-14 ZA ZA916420A patent/ZA916420B/xx unknown
- 1991-08-14 AU AU82422/91A patent/AU644671B2/en not_active Ceased
- 1991-08-14 PT PT98681A patent/PT98681B/pt not_active IP Right Cessation
-
1998
- 1998-03-11 GR GR970402371T patent/GR3026315T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0471612B1 (de) | 1998-01-28 |
DK0471612T3 (da) | 1999-02-22 |
ES2112268T3 (es) | 1998-04-01 |
IE912863A1 (en) | 1992-02-26 |
AU644671B2 (en) | 1993-12-16 |
JP3073803B2 (ja) | 2000-08-07 |
DE69128820T2 (de) | 1998-06-10 |
EP0471612A3 (en) | 1992-05-13 |
AU8242291A (en) | 1992-02-20 |
PT98681B (pt) | 1999-01-29 |
MX9100647A (es) | 1992-04-01 |
HUT59416A (en) | 1992-05-28 |
ATE162797T1 (de) | 1998-02-15 |
EP0471612A2 (de) | 1992-02-19 |
PT98681A (pt) | 1992-07-31 |
GR3026315T3 (en) | 1998-06-30 |
KR920004408A (ko) | 1992-03-27 |
DE69128820D1 (de) | 1998-03-05 |
JPH06340688A (ja) | 1994-12-13 |
CA2049102A1 (fr) | 1992-02-15 |
HU912690D0 (en) | 1992-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69214755D1 (de) | Thiazolidin-2,4-Dionderivate, Verfahren zu deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen | |
ES2190469T3 (es) | Derivados de isocumarina y su uso en farmacos. | |
ZA916420B (en) | 19-nor steroids having a carbonated chain containing an amide function in position 11 beta,their preparation,their use as medicaments and the pharmaceutical compositions containing them | |
DE69131813D1 (de) | Amido-3-Pyrazol-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen | |
ATE248582T1 (de) | Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethasondipropionat | |
ATE104271T1 (de) | 2-(2-hydroxy-3phenoxypropylamino)ethylphenoxyacetamide, verfahren und zwischenprodukte zu deren herstellung. | |
DE69306212D1 (de) | Kardioaktive 17-aryl und 17-heterozyklyl-14 beta-5alpha-Androstane, Androstene und Androstadiene, ein Verfahren zu ihrer Herstellung und pharmazeutische Präperate davon | |
DK509088A (da) | 17-spiro-steroider, deres fremstilling samt laegemidler med indhold deraf | |
DE69209442D1 (de) | Dipeptidderivate und sie enthaltende prophylaktische und therapeutische Mittel für Knochenkrankheiten | |
AU5007290A (en) | New 19-nor steroids having in position 11beta a carbonated chain containing an amide or carbamate function, their preparation process and the intermediates of this process, their use as medicaments and the pharmaceutical compositions containing them | |
DK163181C (da) | Analogifremgangsmaade til fremstilling af n,n'-di(arylalkylen)alkylendiaminer eller farmaceutisk acceptable salte deraf | |
ATE150466T1 (de) | Neue 19-nor-steroide mit einer 11-beta- phenoxysulfonamid- oder 11-beta- phenoxysulfonylurea-gruppe, verfahren und zwischenprodukte zu ihrer herstellung sowie medikamenten und pharmazeutische präparate davon | |
DE69707351D1 (de) | Neue 1- oder 6-hydroxylierte Steroide, ein Verfahren zu ihrer Herstellung, ihre Verwendung als Medikamenten und pharmazeutische Präparate davon | |
ATE138385T1 (de) | Neue steroide mit einer an der 17-stelle spiro- kondensierte methylen-laktongruppe, verfahren und zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und pharmazeutische präparate davon | |
DE69016627D1 (de) | Neue Steroidderivate, die ein substituiertes Ethylradikal an der Stelle 10 des Steroids tragen, Verfahren zu ihrer Herstellung, die Verwendung als Arzneimitte, von einer dieser Verbindungenl und pharmazeutische Präparate von dieser Verbindung. | |
IL92268A0 (en) | 14alpha,17alpha,ethanoestratriene derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
ATA234689A (de) | Neue 2-carbonyl substituierte n,n'-di(trimethoxybenzoyl)piperazine, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen | |
ATE145333T1 (de) | Hirudin enthaltende orale arzneimittel | |
DE59003718D1 (de) | Neue amidingruppen-haltige diphosphonsäurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel. | |
ATA234589A (de) | Neue 2-methoxycarbonyl substituierte n,n'-di(trimethoxybenzoyl)piperazine, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen | |
DE69206460D1 (de) | Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen. | |
EP0271447A3 (en) | Preventive measures for preventing the "bovine complex respiratory disease" by administering interferon | |
ATE145647T1 (de) | Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen | |
ATE106873T1 (de) | Pyridylsulfonylharnstoff- und pyridylsulfonylthioharnstoff-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
DE59107442D1 (de) | Substituierte 3-Thia- bzw. 3-Oxa-alkyl-Flavone, Verfahren zu ihrer Herstellung, Verwendung derselben, Arzneimittel auf Basis dieser Verbindungen sowie Zwischenprodukte |