ZA915584B - Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer - Google Patents

Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer

Info

Publication number
ZA915584B
ZA915584B ZA915584A ZA915584A ZA915584B ZA 915584 B ZA915584 B ZA 915584B ZA 915584 A ZA915584 A ZA 915584A ZA 915584 A ZA915584 A ZA 915584A ZA 915584 B ZA915584 B ZA 915584B
Authority
ZA
South Africa
Prior art keywords
polypeptide
protein
delivery system
drug delivery
biodegradable polymer
Prior art date
Application number
ZA915584A
Other languages
English (en)
Inventor
Patrick P Deluca
P Deluca Patrick
Original Assignee
Univ Kentucky Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kentucky Res Found filed Critical Univ Kentucky Res Found
Publication of ZA915584B publication Critical patent/ZA915584B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Adjustment And Processing Of Grains (AREA)
ZA915584A 1990-07-19 1991-07-17 Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer ZA915584B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55442790A 1990-07-19 1990-07-19

Publications (1)

Publication Number Publication Date
ZA915584B true ZA915584B (en) 1992-04-29

Family

ID=24213291

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA915584A ZA915584B (en) 1990-07-19 1991-07-17 Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer

Country Status (17)

Country Link
US (2) US6306406B1 (fr)
EP (1) EP0467389B1 (fr)
JP (1) JPH05103838A (fr)
AT (1) ATE185269T1 (fr)
AU (1) AU656897B2 (fr)
CA (1) CA2046830C (fr)
CS (1) CS224891A3 (fr)
DE (1) DE69131677T2 (fr)
DK (1) DK0467389T3 (fr)
ES (1) ES2138584T3 (fr)
FI (1) FI104954B (fr)
GR (1) GR3032056T3 (fr)
MX (1) MX9100249A (fr)
NO (1) NO304411B1 (fr)
NZ (1) NZ238951A (fr)
PT (1) PT98397B (fr)
ZA (1) ZA915584B (fr)

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ATE185269T1 (de) 1999-10-15
DK0467389T3 (da) 2000-02-28
NO912769D0 (no) 1991-07-15
FI913455A0 (fi) 1991-07-17
NO304411B1 (no) 1998-12-14
MX9100249A (es) 1992-02-28
US6306406B1 (en) 2001-10-23
DE69131677T2 (de) 2000-02-24
JPH05103838A (ja) 1993-04-27
EP0467389A3 (fr) 1994-02-02
FI913455A (fi) 1992-01-20
ES2138584T3 (es) 2000-01-16
EP0467389A2 (fr) 1992-01-22
FI104954B (fi) 2000-05-15
NZ238951A (en) 1994-12-22
NO912769L (no) 1992-01-20
CA2046830C (fr) 1999-12-14
CA2046830A1 (fr) 1992-01-20
DE69131677D1 (de) 1999-11-11
GR3032056T3 (en) 2000-03-31
EP0467389B1 (fr) 1999-10-06
AU8046691A (en) 1992-01-23
US20020051808A1 (en) 2002-05-02
PT98397B (pt) 1999-01-29
AU656897B2 (en) 1995-02-23
CS224891A3 (en) 1992-03-18
PT98397A (pt) 1992-05-29

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