ZA915366B - Diphenylmethyl piperazine derivatives - Google Patents
Diphenylmethyl piperazine derivativesInfo
- Publication number
- ZA915366B ZA915366B ZA915366A ZA915366A ZA915366B ZA 915366 B ZA915366 B ZA 915366B ZA 915366 A ZA915366 A ZA 915366A ZA 915366 A ZA915366 A ZA 915366A ZA 915366 B ZA915366 B ZA 915366B
- Authority
- ZA
- South Africa
- Prior art keywords
- piperazine derivatives
- action
- diphenylmethyl piperazine
- cardiac muscles
- diphenylmethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2182095A JP2651043B2 (ja) | 1990-07-10 | 1990-07-10 | ジフェニルメチルピペラジン誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA915366B true ZA915366B (en) | 1992-04-29 |
Family
ID=16112265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA915366A ZA915366B (en) | 1990-07-10 | 1991-07-10 | Diphenylmethyl piperazine derivatives |
Country Status (12)
Country | Link |
---|---|
US (1) | US5304558A (ru) |
EP (1) | EP0541802B1 (ru) |
JP (1) | JP2651043B2 (ru) |
CN (1) | CN1037840C (ru) |
AT (1) | ATE112764T1 (ru) |
AU (1) | AU8212591A (ru) |
CA (1) | CA2087032C (ru) |
DE (1) | DE69104615T2 (ru) |
RU (1) | RU2091379C1 (ru) |
TW (1) | TW198717B (ru) |
WO (1) | WO1992000962A1 (ru) |
ZA (1) | ZA915366B (ru) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5658963A (en) * | 1995-02-02 | 1997-08-19 | Bisco, Inc. | One-component primer/bonding-resin systems |
ATE349212T1 (de) | 1999-09-30 | 2007-01-15 | Noboru Kaneko | Mittel gegen krebs |
IL151923A0 (en) * | 2000-03-31 | 2003-04-10 | Pfizer Prod Inc | Novel piperazine derivatives |
US7393652B2 (en) * | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
US7879840B2 (en) * | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US7718644B2 (en) * | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
US20060293266A1 (en) * | 2000-05-10 | 2006-12-28 | The Trustees Of Columbia | Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure |
US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
US20040048780A1 (en) * | 2000-05-10 | 2004-03-11 | The Trustees Of Columbia University In The City Of New York | Method for treating and preventing cardiac arrhythmia |
US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US6489125B1 (en) * | 2000-05-10 | 2002-12-03 | The Trustees Of Columbia University In The City Of New York | Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor |
EP1423381B1 (en) * | 2001-09-06 | 2007-01-03 | Schering Corporation | 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases |
US7544678B2 (en) * | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
JP2007525165A (ja) | 2003-03-07 | 2007-09-06 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | タイプ1ライアノジン受容体に基づく方法 |
US8710045B2 (en) * | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
JP5318938B2 (ja) | 2011-06-09 | 2013-10-16 | 株式会社アエタスファルマ | ジフェニルメチルピペラジン誘導体、及びそれを用いた医薬組成物 |
JP6021616B2 (ja) * | 2012-12-04 | 2016-11-09 | 株式会社アエタスファルマ | 3−ピペラジニル−1−ピペリジニル−プロパン誘導体及びそれを含有してなる医薬組成物 |
KR102257892B1 (ko) | 2014-11-26 | 2021-05-28 | 삼성전자주식회사 | 개선된 nfc 안테나 및 그 안테나를 갖는 전자 장치 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR65270B (en) * | 1978-10-10 | 1980-07-31 | Fujisawa Pharmaceutical Co | Isatin derivatives and processes for the preparation thereof |
DE3536797A1 (de) * | 1985-10-16 | 1987-04-16 | Studiengesellschaft Kohle Mbh | Verfahren zur herstellung von halogen-magnesium-alanat und dessen verwendung |
HU198052B (en) * | 1986-02-14 | 1989-07-28 | Sandoz Ag | Process for producing purine derivatives substituted by side chain containing piperazinyl ring and pharmaceutical compositions comprising such compounds |
ZA871078B (en) * | 1986-02-14 | 1988-09-28 | Sandoz Ltd | Purine derivatives,their preparation and medicaments containing them |
US4885300A (en) * | 1988-03-03 | 1989-12-05 | Ortho Pharmaceutical Corporation | 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives |
US5215987A (en) * | 1990-04-23 | 1993-06-01 | Ortho Pharmaceutical Corporation | Substituted benzhydryl 2-hydroxypropyl piperazine derivatives |
-
1990
- 1990-07-10 JP JP2182095A patent/JP2651043B2/ja not_active Expired - Lifetime
-
1991
- 1991-07-10 US US07/958,366 patent/US5304558A/en not_active Expired - Lifetime
- 1991-07-10 CA CA002087032A patent/CA2087032C/en not_active Expired - Lifetime
- 1991-07-10 CN CN91105588A patent/CN1037840C/zh not_active Expired - Lifetime
- 1991-07-10 AT AT91912316T patent/ATE112764T1/de not_active IP Right Cessation
- 1991-07-10 ZA ZA915366A patent/ZA915366B/xx unknown
- 1991-07-10 AU AU82125/91A patent/AU8212591A/en not_active Abandoned
- 1991-07-10 WO PCT/JP1991/000924 patent/WO1992000962A1/ja active IP Right Grant
- 1991-07-10 DE DE69104615T patent/DE69104615T2/de not_active Expired - Lifetime
- 1991-07-10 EP EP91912316A patent/EP0541802B1/en not_active Expired - Lifetime
- 1991-07-10 RU RU9192016555A patent/RU2091379C1/ru active
- 1991-09-03 TW TW080106989A patent/TW198717B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0541802B1 (en) | 1994-10-12 |
AU8212591A (en) | 1992-02-04 |
DE69104615D1 (de) | 1994-11-17 |
DE69104615T2 (de) | 1995-03-23 |
RU2091379C1 (ru) | 1997-09-27 |
JP2651043B2 (ja) | 1997-09-10 |
JPH0469377A (ja) | 1992-03-04 |
ATE112764T1 (de) | 1994-10-15 |
CN1037840C (zh) | 1998-03-25 |
EP0541802A4 (en) | 1993-05-26 |
EP0541802A1 (en) | 1993-05-19 |
CN1058963A (zh) | 1992-02-26 |
TW198717B (ru) | 1993-01-21 |
CA2087032C (en) | 1999-06-15 |
US5304558A (en) | 1994-04-19 |
CA2087032A1 (en) | 1992-01-11 |
WO1992000962A1 (fr) | 1992-01-23 |
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