ZA913530B - Biocatalytic process for the production of l-(-)carnitine from crotonobetaine and strains of proteeae for use in said process - Google Patents

Biocatalytic process for the production of l-(-)carnitine from crotonobetaine and strains of proteeae for use in said process

Info

Publication number
ZA913530B
ZA913530B ZA913530A ZA913530A ZA913530B ZA 913530 B ZA913530 B ZA 913530B ZA 913530 A ZA913530 A ZA 913530A ZA 913530 A ZA913530 A ZA 913530A ZA 913530 B ZA913530 B ZA 913530B
Authority
ZA
South Africa
Prior art keywords
crotonobetaine
carnitine
strains
proteeae
production
Prior art date
Application number
ZA913530A
Other languages
English (en)
Inventor
Stuart Shapiro
Shapiro Stuart
Manrico Bernardini
Bernardini Manrico
Charles J Sih
J Sih Charles
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ZA913530B publication Critical patent/ZA913530B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/007Carnitine; Butyrobetaine; Crotonobetaine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • C12N9/2417Alpha-amylase (3.2.1.1.) from microbiological source
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/873Proteus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA913530A 1990-05-14 1991-05-10 Biocatalytic process for the production of l-(-)carnitine from crotonobetaine and strains of proteeae for use in said process ZA913530B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47953A IT1240833B (it) 1990-05-14 1990-05-14 Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento

Publications (1)

Publication Number Publication Date
ZA913530B true ZA913530B (en) 1992-02-26

Family

ID=11263576

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913530A ZA913530B (en) 1990-05-14 1991-05-10 Biocatalytic process for the production of l-(-)carnitine from crotonobetaine and strains of proteeae for use in said process

Country Status (14)

Country Link
US (1) US5300430A (de)
EP (1) EP0457735B1 (de)
JP (1) JP3167739B2 (de)
KR (1) KR0135116B1 (de)
AT (1) ATE125570T1 (de)
CA (1) CA2042425C (de)
DE (1) DE69111511T2 (de)
DK (1) DK0457735T3 (de)
ES (1) ES2075408T3 (de)
HK (1) HK1005888A1 (de)
IE (1) IE62149B1 (de)
IT (1) IT1240833B (de)
PT (1) PT97659B (de)
ZA (1) ZA913530B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1240833B (it) * 1990-05-14 1993-12-17 Sigma Tau Ind Farmaceuti Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento
IT1261230B (it) * 1993-04-08 1996-05-09 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.
KR100346293B1 (ko) * 1993-10-08 2002-11-30 론자 아게 부티로베타인/크로토노베타인-l-카르니틴대사유전자와l-카르니틴의미생물학적제조에사용되는그것의용도
DE69600978T2 (de) * 1995-03-28 1999-04-15 Tanabe Seiyaku Co., Ltd., Osaka Verfahren zur Herstellung von D-Aminosäuren
KR100255039B1 (ko) 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
US6337197B2 (en) * 1998-10-27 2002-01-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Coenzymes useful for the synthesis of L-carnitine
PT1151130E (pt) 1998-10-27 2005-06-30 Sigma Tau Ind Farmaceuti Coenzima utilizada na sintese de l-carnitina
US6746530B2 (en) 2001-08-02 2004-06-08 Chunghwa Pictures Tubes, Ltd. High contrast, moisture resistant antistatic/antireflective coating for CRT display screen
ATE454460T1 (de) * 2005-04-15 2010-01-15 Council Scient Ind Res Chemisch-enzymatisches verfahren zur stereoselektiven herstellung von (r)-gamma-amino- beta-hydroxybuttersäure ((r)-gabob) und (r)- carnitin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc L−カルニチンの製造法
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
EP0320460B1 (de) * 1987-10-26 1994-04-27 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Verfahren zur Isolierung des Enzyms Karnitin-Hydrolyase von zur Familie der Enterobakteriaceae gehörenden Stämmen und Verwendung des immobilisierten Enzyms zur Herstellung von L(-)Karnitin
IT1240833B (it) * 1990-05-14 1993-12-17 Sigma Tau Ind Farmaceuti Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento

Also Published As

Publication number Publication date
DK0457735T3 (da) 1995-09-11
IE911637A1 (en) 1991-11-20
EP0457735A1 (de) 1991-11-21
ES2075408T3 (es) 1995-10-01
IT9047953A0 (it) 1990-05-14
CA2042425A1 (en) 1991-11-15
CA2042425C (en) 2000-07-11
PT97659A (pt) 1992-05-29
KR0135116B1 (ko) 1998-04-15
IT1240833B (it) 1993-12-17
EP0457735B1 (de) 1995-07-26
HK1005888A1 (en) 1999-01-29
IT9047953A1 (it) 1991-11-14
JPH04228065A (ja) 1992-08-18
DE69111511T2 (de) 1996-01-04
PT97659B (pt) 1998-09-30
DE69111511D1 (de) 1995-08-31
KR910020171A (ko) 1991-12-19
US5300430A (en) 1994-04-05
IE62149B1 (en) 1994-12-14
JP3167739B2 (ja) 2001-05-21
ATE125570T1 (de) 1995-08-15

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