ZA909043B - Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders - Google Patents

Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders

Info

Publication number
ZA909043B
ZA909043B ZA909043A ZA909043A ZA909043B ZA 909043 B ZA909043 B ZA 909043B ZA 909043 A ZA909043 A ZA 909043A ZA 909043 A ZA909043 A ZA 909043A ZA 909043 B ZA909043 B ZA 909043B
Authority
ZA
South Africa
Prior art keywords
asthma
treatment
analogs
skin disorders
certain skin
Prior art date
Application number
ZA909043A
Other languages
English (en)
Inventor
John B Cheng
B Cheng John
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA909043B publication Critical patent/ZA909043B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA909043A 1989-11-13 1990-11-12 Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders ZA909043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/005221 WO1991007177A1 (en) 1989-11-13 1989-11-13 Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders

Publications (1)

Publication Number Publication Date
ZA909043B true ZA909043B (en) 1992-06-24

Family

ID=22215372

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909043A ZA909043B (en) 1989-11-13 1990-11-12 Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders

Country Status (17)

Country Link
US (1) US5342842A (ja)
EP (1) EP0428313B1 (ja)
JP (2) JPH0662412B2 (ja)
KR (1) KR930001832B1 (ja)
AT (1) ATE101040T1 (ja)
AU (1) AU627631B2 (ja)
CA (1) CA2029704C (ja)
DE (1) DE69006452T2 (ja)
DK (1) DK0428313T3 (ja)
HU (1) HU212311B (ja)
IE (1) IE63472B1 (ja)
IL (1) IL96260A (ja)
MY (1) MY111474A (ja)
NZ (1) NZ236038A (ja)
PT (1) PT95854B (ja)
WO (2) WO1991007177A1 (ja)
ZA (1) ZA909043B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
JP3100984B2 (ja) * 1992-12-02 2000-10-23 ファイザー・インク． 選択的ｐｄｅ▲下ｉ▼▲下ｖ▼阻害物質としてのカテコールジエーテル類
US5814651A (en) * 1992-12-02 1998-09-29 Pfizer Inc. Catechol diethers as selective PDEIV inhibitors
US5482944A (en) * 1993-07-13 1996-01-09 Pfizer Inc. Pyrimidones and imidazolinones for treatment of shock
US5502072A (en) * 1993-11-26 1996-03-26 Pfizer Inc. Substituted oxindoles
ES2139754T3 (es) * 1993-11-26 2000-02-16 Pfizer 3-fenil-2-isoxazolinas como agentes antiinflamatorios.
JPH09505081A (ja) * 1994-03-09 1997-05-20 ファイザー・インコーポレーテッド ５−リポキシゲナーゼ阻害物質としてのイソキサゾリン化合物
ES2118557T3 (es) * 1994-03-09 1998-09-16 Pfizer Compuestos de isoxazolina como inhibidores de la liberacion de tnf.
US5563143A (en) * 1994-09-21 1996-10-08 Pfizer Inc. Catechol diether compounds as inhibitors of TNF release
EP2223920A3 (en) 1996-06-19 2011-09-28 Aventis Pharma Limited Substituted azabicyclic compounds
CA2264685C (en) * 1996-08-27 2002-10-15 Kyoji Noda 2-phenylmorpholin-5-one derivatives and pharmaceutical composition comprising the same
EP2258689A1 (en) * 2000-03-16 2010-12-08 Biolipox AB Benzylated PDE4 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2401446A1 (de) * 1973-01-16 1974-07-25 Voorhees Pharmazeutische zubereitungen zur linderung von hautproliferationserkrankungen
SU888821A3 (ru) * 1976-12-03 1981-12-07 Шеринг Аг (Инофирма) Способ получени 5-(замещенный фенил)-оксазолидинонов или их серусодержащих аналогов
DE3315797A1 (de) * 1983-04-30 1984-10-31 Beiersdorf Ag, 2000 Hamburg Substituierte phenyl-2-(1h)-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
GB8416140D0 (en) * 1984-06-25 1984-08-01 Fujisawa Pharmaceutical Co Pyrimidinone derivatives
HU215433B (hu) * 1986-04-29 2000-05-28 Pfizer Inc. Eljárás új 2-oxo-5-fenil-pirimidin-származékok előállítására

Also Published As

Publication number Publication date
IE904058A1 (en) 1991-05-22
IL96260A (en) 1995-11-27
US5342842A (en) 1994-08-30
WO1991007178A1 (en) 1991-05-30
HU9201575D0 (en) 1993-04-28
DK0428313T3 (da) 1994-03-07
JPH0662412B2 (ja) 1994-08-17
EP0428313B1 (en) 1994-02-02
CA2029704A1 (en) 1991-05-14
PT95854B (pt) 1997-11-28
NZ236038A (en) 1997-03-24
WO1991007177A1 (en) 1991-05-30
MY111474A (en) 2000-06-30
HU212311B (en) 1996-05-28
IE63472B1 (en) 1995-04-19
JP2514163B2 (ja) 1996-07-10
PT95854A (pt) 1991-09-13
DE69006452D1 (de) 1994-03-17
KR930001832B1 (ko) 1993-03-15
EP0428313A3 (en) 1991-11-06
JPH03209322A (ja) 1991-09-12
KR910009259A (ko) 1991-06-28
EP0428313A2 (en) 1991-05-22
IL96260A0 (en) 1991-08-16
JPH0748255A (ja) 1995-02-21
DE69006452T2 (de) 1994-05-11
AU6653690A (en) 1991-08-01
HUT70052A (en) 1995-09-28
AU627631B2 (en) 1992-08-27
CA2029704C (en) 1995-02-07
ATE101040T1 (de) 1994-02-15

Similar Documents

Publication Publication Date Title
PL292101A1 (en) Method of obtaining novel derivatives of cyclopentylpurine and cyclopentylpyrimidine
HK1008328A1 (en) Endothelin antagonists
ZA944739B (en) Amide and urea derivatives having anti-hypercholesteremic activity their preparation and their therapeutic uses
AU627631B2 (en) Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders
AU2868689A (en) Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
GR3005990T3 (ja)
ES2007064A6 (es) Un procedimiento para la obtencion de 4(3h)-oxo-5,6,8-tetrahidropirido (2,3-d)pirimidinas
AU641686B2 (en) Benzanilides
GR3019893T3 (en) Novel S-adenosyl methionine decarboxylase inhibitors
DE3666223D1 (en) Anticonvulsant agents
FI103885B1 (fi) Menetelmä terapeuttisesti aktiivisten 1-bentsyyli-4-fenyylipiperatsiinijohdannaisten valmistamiseksi ja välituotteina käyttökelpoisia yhdisteitä
HU912216D0 (en) Process for the production of purinyl-and pirimidinyl - tetrahydrofurane derivatives and medical preparations containing them
IE882142L (en) Naphthothiazepine derivatives and preparation thereof
EP0449011A3 (en) Stereoselective process for the preparation of 2-amino-ethanol derivatives having a central analgesic activity and intermediates thereof
EP0301466A3 (en) Uricosuric composition
HK34095A (en) Use of 2-oxo-imidazolidine derivatives in the treatment of kidney diseases
MY101746A (en) 1,5-benzothiazepine derivatives, a process for preparing the same, pharmaceutical compositions as well as the use thereof.
LU88449I2 (fr) Fleroxacine et ses dérivés pharmaceutiquement acceptables.