ZA908641B - (n-phthalimidoalkyl)piperidines - Google Patents

(n-phthalimidoalkyl)piperidines

Info

Publication number
ZA908641B
ZA908641B ZA908641A ZA908641A ZA908641B ZA 908641 B ZA908641 B ZA 908641B ZA 908641 A ZA908641 A ZA 908641A ZA 908641 A ZA908641 A ZA 908641A ZA 908641 B ZA908641 B ZA 908641B
Authority
ZA
South Africa
Prior art keywords
phthalimidoalkyl
piperidines
Prior art date
Application number
ZA908641A
Other languages
English (en)
Inventor
Engelbert Ciganek
Ciganek Engelbert
Sang William Tam
William Tam Sang
Ann Sorrentino Wright
Sorrentino Wright Ann
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of ZA908641B publication Critical patent/ZA908641B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA908641A 1989-10-27 1990-10-29 (n-phthalimidoalkyl)piperidines ZA908641B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42809789A 1989-10-27 1989-10-27

Publications (1)

Publication Number Publication Date
ZA908641B true ZA908641B (en) 1992-06-24

Family

ID=23697544

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908641A ZA908641B (en) 1989-10-27 1990-10-29 (n-phthalimidoalkyl)piperidines

Country Status (5)

Country Link
EP (1) EP0497843A4 (ko)
KR (1) KR927002347A (ko)
CA (1) CA2069318A1 (ko)
WO (1) WO1991006297A1 (ko)
ZA (1) ZA908641B (ko)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5162341A (en) * 1991-02-22 1992-11-10 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists for treatment of amphetamine abuse
US5180729A (en) * 1991-02-22 1993-01-19 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists for treatment of cocaine abuse
DK0637306T3 (da) * 1992-04-23 2001-07-30 Merrell Pharma Inc 4-Imidomethyl-1-[2'-phenyl-2'-oxoethyl]-piperidiner som serotonin-5HT2-antagonister, deres fremstilling og anvendelse til terapi
FR2713639B1 (fr) * 1993-12-09 1996-08-30 Irj Nouveaux dérivés de 2-arylalkényl-azacycloalkanes ligands aux récepteurs sigma, leur procédé de préparation et leur application en thérapeutique.
GB9416571D0 (en) * 1994-08-16 1994-10-12 Battelle Memorial Institute Novel alkylamino derivatives as sigma 2 selective ligands
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
AU760800B2 (en) * 1997-10-24 2003-05-22 Warner-Lambert Company Method for treating disease-related or drug-induced dyskinesias
IL151533A0 (en) * 2000-02-29 2003-04-10 Mitsubishi Pharma Corp Novel cyclic amide derivatives
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6656953B2 (en) * 2000-12-06 2003-12-02 Sepracor Inc. 4,4-Disubstituted piperidines, and methods of use thereof
TWI263640B (en) * 2001-12-19 2006-10-11 Bristol Myers Squibb Co Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2012012543A1 (en) * 2010-07-20 2012-01-26 Cyrenaic Pharmaceuticals Inc. Methods of use cyclic amide derivatives to treat sigma receptor-mediated disorders
RS64819B1 (sr) * 2010-07-20 2023-12-29 Minerva Neurosciences Inc Metode upotrebe derivata cikličnih amida za lečenje šizofrenije i njenih simptoma
MY185516A (en) 2014-12-02 2021-05-19 Mitsubishi Tanabe Pharma Corp Compositions and methods for treating schizophrenia
CN111511353A (zh) 2017-06-21 2020-08-07 田边三菱制药株式会社 耐胃液的控释口服剂型
BR112021002654A2 (pt) 2018-08-21 2021-05-04 Minerva Neurosciences, Inc. uso de roluperidona para tratar sintomas e distúrbios negativos, aumentar a neuroplasticidade e promover neuroproteção
US11919860B1 (en) 2023-10-06 2024-03-05 King Faisal University 1-2(-(substituted phenyl)-2-oxoethyl)-4-(isopropoxycarbonyl)pyridin-1-ium bromides as anti-tubercular agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425578A (en) * 1972-10-21 1976-02-18 Wyeth John & Brother Ltd Piperidine derivatives
SE7907121L (sv) * 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
US4495194A (en) * 1982-11-12 1985-01-22 Mead Johnson & Company Antihypertensive isoindole derivatives
NZ216720A (en) * 1985-07-08 1990-09-26 Bristol Myers Co Diazinylpiperidine derivatives and pharmaceutical compositions
DE3717561A1 (de) * 1987-05-25 1988-12-08 Thomae Gmbh Dr K Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
JP2660407B2 (ja) * 1986-09-26 1997-10-08 住友製薬株式会社 新規なイミド誘導体
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi

Also Published As

Publication number Publication date
EP0497843A1 (en) 1992-08-12
KR927002347A (ko) 1992-09-03
WO1991006297A1 (en) 1991-05-16
CA2069318A1 (en) 1991-04-28
EP0497843A4 (en) 1992-09-23

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