ZA906251B - A novel substituted pyrazine,formulations thereof and use in medicine - Google Patents

A novel substituted pyrazine,formulations thereof and use in medicine

Info

Publication number
ZA906251B
ZA906251B ZA906251A ZA906251A ZA906251B ZA 906251 B ZA906251 B ZA 906251B ZA 906251 A ZA906251 A ZA 906251A ZA 906251 A ZA906251 A ZA 906251A ZA 906251 B ZA906251 B ZA 906251B
Authority
ZA
South Africa
Prior art keywords
formulations
medicine
novel substituted
substituted pyrazine
pyrazine
Prior art date
Application number
ZA906251A
Other languages
English (en)
Inventor
Raymond Baker
Baker Raymond
John Saunders
Saunders John
Leslie J Street
J Street Leslie
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of ZA906251B publication Critical patent/ZA906251B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA906251A 1989-08-08 1990-08-08 A novel substituted pyrazine,formulations thereof and use in medicine ZA906251B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898918060A GB8918060D0 (en) 1989-08-08 1989-08-08 Therapeutic agents

Publications (1)

Publication Number Publication Date
ZA906251B true ZA906251B (en) 1991-07-31

Family

ID=10661305

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA906251A ZA906251B (en) 1989-08-08 1990-08-08 A novel substituted pyrazine,formulations thereof and use in medicine

Country Status (13)

Country Link
US (1) US5073557A (xx)
EP (1) EP0416754A3 (xx)
JP (1) JPH03135979A (xx)
KR (1) KR910004617A (xx)
AU (1) AU6083090A (xx)
CA (1) CA2022885A1 (xx)
FI (1) FI903919A0 (xx)
GB (1) GB8918060D0 (xx)
IE (1) IE902875A1 (xx)
IL (1) IL95312A0 (xx)
NO (1) NO903484L (xx)
PT (1) PT94921A (xx)
ZA (1) ZA906251B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK72790D0 (da) * 1990-03-21 1990-03-21 Ferrosan As Heterocycliske forbindelser, deres fremstilling og anvendelse
GB9017353D0 (en) * 1990-08-08 1990-09-19 Merck Sharp & Dohme Chemical process
CA2050264A1 (en) * 1990-08-30 1992-03-01 Raymond Baker Substituted pyrazine and its salts, compositions containing them and their use in medicine
GB9201749D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Plc Medicaments
US5478939A (en) * 1994-07-20 1995-12-26 American Cyanamid Company (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4442096A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 2-(Substituted)amino-3-cyano-5-halo-6-(substituted)-pyrazine antimicrobial compounds, compositions and use
DE3515709C1 (de) * 1985-05-02 1986-12-18 Union Rheinische Braunkohlen Kraftstoff AG, 5000 Köln Verfahren zum Reinigen von fluessigem Schwefel
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
DE58906678D1 (de) * 1988-07-28 1994-02-24 Ciba Geigy Kupfer- und Nickeldihalogenidkomplexe, Verfahren zu deren Herstellung und deren Verwendung.

Also Published As

Publication number Publication date
EP0416754A3 (en) 1991-11-27
GB8918060D0 (en) 1989-09-20
FI903919A0 (fi) 1990-08-08
US5073557A (en) 1991-12-17
NO903484L (no) 1991-02-11
CA2022885A1 (en) 1991-02-09
KR910004617A (ko) 1991-03-29
EP0416754A2 (en) 1991-03-13
IL95312A0 (en) 1991-06-30
IE902875A1 (en) 1991-02-27
JPH03135979A (ja) 1991-06-10
NO903484D0 (no) 1990-08-08
PT94921A (pt) 1991-04-18
AU6083090A (en) 1991-02-14

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