ZA905043B - Novel vitamin d analogues - Google Patents

Novel vitamin d analogues

Info

Publication number
ZA905043B
ZA905043B ZA905043A ZA905043A ZA905043B ZA 905043 B ZA905043 B ZA 905043B ZA 905043 A ZA905043 A ZA 905043A ZA 905043 A ZA905043 A ZA 905043A ZA 905043 B ZA905043 B ZA 905043B
Authority
ZA
South Africa
Prior art keywords
formula
compounds
hydroxyl group
carbons
diseases
Prior art date
Application number
ZA905043A
Other languages
English (en)
Inventor
Martin John Calverley
John Calverley Martin
Ernst Torndal Binderup
Torndal Binderup Ernst
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of ZA905043B publication Critical patent/ZA905043B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
ZA905043A 1989-06-29 1990-06-28 Novel vitamin d analogues ZA905043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898914963A GB8914963D0 (en) 1989-06-29 1989-06-29 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA905043B true ZA905043B (en) 1991-05-29

Family

ID=10659278

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA905043A ZA905043B (en) 1989-06-29 1990-06-28 Novel vitamin d analogues

Country Status (15)

Country Link
EP (1) EP0479871B1 (fr)
JP (1) JP2807086B2 (fr)
KR (1) KR100195573B1 (fr)
AT (1) ATE88465T1 (fr)
AU (1) AU629666B2 (fr)
CA (1) CA2051418C (fr)
DE (1) DE69001437T2 (fr)
DK (1) DK0479871T3 (fr)
ES (1) ES2055438T3 (fr)
FI (1) FI93723C (fr)
GB (1) GB8914963D0 (fr)
IE (1) IE63665B1 (fr)
NZ (1) NZ234216A (fr)
WO (1) WO1991000271A1 (fr)
ZA (1) ZA905043B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
CA2062520C (fr) * 1991-03-11 1998-08-11 Hector F. Deluca Synthese de composes de type 1-alpha-hydroxy-secosterol
US5486509A (en) * 1991-06-28 1996-01-23 University Of Miami Method of preventing and treating chemotherapy-induced alopecia
EP0566030B1 (fr) * 1992-04-14 1999-11-10 Kuraray Co., Ltd. Procédé pour la préparation des oléfins optiquement actifs
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
US5552392A (en) * 1993-11-03 1996-09-03 Wisconsin Alumni Research Foundation Method of treating hypoparathyroidism with (20S) vitamin D compounds
GB9524812D0 (en) * 1995-12-05 1996-02-07 Leo Pharm Prod Ltd Chemical compounds
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
GB9622590D0 (en) * 1996-10-30 1997-01-08 Leo Pharm Prod Ltd Chemical compounds
US20030018017A1 (en) * 2001-01-25 2003-01-23 Deluca Hector F. Method of treatment of type I diabetes
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
WO2010060197A1 (fr) * 2008-11-26 2010-06-03 Cytochroma Inc. Procédé pour synthétiser des analogues de vitamine d
ES2674336B1 (es) * 2016-12-28 2019-04-11 Laboratorios Vinas S A Procedimiento para reducir derivados carbonilicos de vitamina d y uso correspondiente

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004527A1 (fr) * 1983-05-09 1984-11-22 Wisconsin Alumni Res Found PROCEDE DE PREPARATION DE LA VITAMINE D21alpha,25-DIHYDROXYLEE ET DES COMPOSES APPARENTES
RU2057117C1 (ru) * 1988-04-29 1996-03-27 Висконсин Алюмни Рисерч Фаундейшн ГОМОЛОГИ 1α - ГИДРОКСИВИТАМИНА D3 С НЕНАСЫЩЕННОЙ БОКОВОЙ ЦЕПЬЮ, КОМПОЗИЦИЯ, СПОСОБСТВУЮЩАЯ СТИМУЛЯЦИИ И УСИЛЕНИЮ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА, СПОСОБ СТИМУЛЯЦИИ И УСИЛЕНИЯ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА
US4851401A (en) * 1988-07-14 1989-07-25 Wisconsin Alumni Research Foundation Novel cyclopentano-vitamin D analogs

Also Published As

Publication number Publication date
EP0479871B1 (fr) 1993-04-21
ATE88465T1 (de) 1993-05-15
NZ234216A (en) 1993-03-26
KR920701147A (ko) 1992-08-11
AU629666B2 (en) 1992-10-08
AU5963790A (en) 1991-01-17
ES2055438T3 (es) 1994-08-16
DK0479871T3 (da) 1993-06-14
JP2807086B2 (ja) 1998-09-30
EP0479871A1 (fr) 1992-04-15
IE63665B1 (en) 1995-05-31
CA2051418C (fr) 2002-02-05
KR100195573B1 (en) 1999-06-15
GB8914963D0 (en) 1989-08-23
IE902027A1 (en) 1991-06-19
DE69001437D1 (de) 1993-05-27
JPH04506351A (ja) 1992-11-05
FI93723C (fi) 1995-05-26
FI916150A0 (fi) 1991-12-27
IE902027L (en) 1990-12-29
DE69001437T2 (de) 1993-08-19
FI93723B (fi) 1995-02-15
CA2051418A1 (fr) 1990-12-30
WO1991000271A1 (fr) 1991-01-10

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