ZA901849B - 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline - Google Patents

3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline

Info

Publication number
ZA901849B
ZA901849B ZA901849A ZA901849A ZA901849B ZA 901849 B ZA901849 B ZA 901849B ZA 901849 A ZA901849 A ZA 901849A ZA 901849 A ZA901849 A ZA 901849A ZA 901849 B ZA901849 B ZA 901849B
Authority
ZA
South Africa
Prior art keywords
morpholinyl
anthracycline
methoxy
Prior art date
Application number
ZA901849A
Other languages
English (en)
Inventor
Antonino Suarato
Suarato Antonino
Francesco Angelucci
Angelucci Francesco
Alberto Bargiotti
Bargiotti Alberto
Maria Grandi
Grandi Maria
Gabriella Pezzoni
Pezzoni Gabriella
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA901849B publication Critical patent/ZA901849B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA901849A 1989-03-13 1990-03-09 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline ZA901849B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898905668A GB8905668D0 (en) 1989-03-13 1989-03-13 New 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline derivatives

Publications (1)

Publication Number Publication Date
ZA901849B true ZA901849B (en) 1990-12-28

Family

ID=10653210

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA901849A ZA901849B (en) 1989-03-13 1990-03-09 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline

Country Status (14)

Country Link
EP (3) EP0387661A3 (sv)
JP (1) JPH03504609A (sv)
KR (1) KR920700216A (sv)
AU (1) AU632102B2 (sv)
CA (1) CA2028841A1 (sv)
FI (1) FI96693C (sv)
GB (1) GB8905668D0 (sv)
HU (1) HU207339B (sv)
IL (1) IL93676A (sv)
MY (1) MY106176A (sv)
NZ (1) NZ232829A (sv)
PT (1) PT93414A (sv)
WO (1) WO1990010639A2 (sv)
ZA (1) ZA901849B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019933D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 13-dihydro-3'-(2-alkoxy-4-morphlinyl)anthracyclines
CN102050856B (zh) * 2009-11-03 2014-04-30 天津和美生物技术有限公司 具有高活性的表阿霉素的衍生物及其制备和应用
RU2563638C2 (ru) * 2010-12-02 2015-09-20 НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. Способ получения производных морфолинилантрациклина
DK2991993T3 (en) * 2013-04-29 2018-07-30 Nerviano Medical Sciences Srl NEW MORPHOLINYLANTHRACYCLINE DERIVATIVES
ES2735375T3 (es) * 2014-11-05 2019-12-18 Nerviano Medical Sciences Srl Derivados funcionalizados de morfolinil antraciclina

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348388A (en) 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
US4301277A (en) * 1980-10-20 1981-11-17 Sri International 3-Deamino-3-(4-morpholinyl) derivatives of daunorubicin and doxorubicin
JPS57163393A (en) * 1981-03-27 1982-10-07 Microbial Chem Res Found Novel anthracyclin derivative and its preparation
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
GB2140006A (en) * 1983-05-17 1984-11-21 Erba Farmitalia Anthracycline derivatives
EP0131174B1 (en) 1983-07-07 1989-09-13 Beecham Group Plc Substituted phenylglycine derivatives of beta-lactam antibiotics
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
GB8617742D0 (en) 1986-07-21 1986-08-28 Erba Farmitalia 6-amino anthracyclines
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation

Also Published As

Publication number Publication date
FI905594A0 (sv) 1990-11-12
HUT57229A (en) 1991-11-28
HU902267D0 (en) 1991-05-28
CA2028841A1 (en) 1990-09-14
PT93414A (pt) 1990-11-07
EP0387661A2 (en) 1990-09-19
EP0387661A3 (en) 1991-03-06
MY106176A (en) 1995-03-31
AU5190090A (en) 1990-10-09
AU632102B2 (en) 1992-12-17
EP0495528A1 (en) 1992-07-22
IL93676A0 (en) 1990-12-23
KR920700216A (ko) 1992-02-19
HU207339B (en) 1993-03-29
IL93676A (en) 1994-10-21
GB8905668D0 (en) 1989-04-26
FI96693B (sv) 1996-04-30
EP0490878A1 (en) 1992-06-17
WO1990010639A2 (en) 1990-09-20
NZ232829A (en) 1991-03-26
JPH03504609A (ja) 1991-10-09
WO1990010639A3 (en) 1990-10-18
FI96693C (sv) 1996-08-12

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