ZA90140B - Anti-inflammatory 1-heteroaryloxindole-3-carboxamides - Google Patents

Anti-inflammatory 1-heteroaryloxindole-3-carboxamides

Info

Publication number
ZA90140B
ZA90140B ZA90140A ZA90140A ZA90140B ZA 90140 B ZA90140 B ZA 90140B ZA 90140 A ZA90140 A ZA 90140A ZA 90140 A ZA90140 A ZA 90140A ZA 90140 B ZA90140 B ZA 90140B
Authority
ZA
South Africa
Prior art keywords
furyl
thienyl
alkyl
heteroaryloxindole
carboxamides
Prior art date
Application number
ZA90140A
Other languages
English (en)
Inventor
Joseph George Lombardino
George Lombardino Joseph
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA90140B publication Critical patent/ZA90140B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
ZA90140A 1989-01-10 1990-01-09 Anti-inflammatory 1-heteroaryloxindole-3-carboxamides ZA90140B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/000080 WO1990008146A1 (en) 1989-01-10 1989-01-10 Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides

Publications (1)

Publication Number Publication Date
ZA90140B true ZA90140B (en) 1991-08-28

Family

ID=22214773

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90140A ZA90140B (en) 1989-01-10 1990-01-09 Anti-inflammatory 1-heteroaryloxindole-3-carboxamides

Country Status (20)

Country Link
US (1) US5128352A (sv)
EP (1) EP0378357B1 (sv)
JP (1) JPH0678337B2 (sv)
KR (1) KR920006784B1 (sv)
AT (1) ATE100096T1 (sv)
AU (1) AU616090B2 (sv)
CA (1) CA2007651C (sv)
DE (1) DE69005833T2 (sv)
DK (1) DK0378357T3 (sv)
ES (1) ES2062318T3 (sv)
FI (1) FI94247C (sv)
HU (1) HU217072B (sv)
IE (1) IE61796B1 (sv)
IL (1) IL92961A0 (sv)
MY (1) MY106261A (sv)
NO (1) NO178193C (sv)
NZ (1) NZ232038A (sv)
PT (1) PT92801B (sv)
WO (1) WO1990008146A1 (sv)
ZA (1) ZA90140B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE301457T1 (de) * 1995-06-12 2005-08-15 Searle & Co Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor
CA2978823C (en) * 2014-12-29 2023-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3749731A (en) * 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US4176191A (en) * 1977-09-06 1979-11-27 Abbott Laboratories Aminomethylene oxindoles
US4476307A (en) * 1982-09-20 1984-10-09 Pfizer Inc. Heteroylidene indolone compounds
DE3568776D1 (en) * 1984-02-07 1989-04-20 Pfizer 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents
WO1986001510A1 (en) * 1984-08-24 1986-03-13 Pfizer Inc. Tricyclic oxindole antiinflammatory agents
US4644005A (en) * 1984-10-31 1987-02-17 Pfizer Inc. Oxindole antiinflammatory agents
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
US4791129A (en) * 1987-01-20 1988-12-13 Pfizer Inc. 1,3-dicarboxamidooxindoles as analgesic and antiinflammatory agents

Also Published As

Publication number Publication date
FI913325A0 (sv) 1991-07-09
DK0378357T3 (da) 1994-02-14
FI94247B (sv) 1995-04-28
EP0378357A1 (en) 1990-07-18
AU616090B2 (en) 1991-10-17
CA2007651C (en) 1997-08-19
WO1990008146A1 (en) 1990-07-26
US5128352A (en) 1992-07-07
IL92961A0 (en) 1990-09-17
NO178193B (no) 1995-10-30
NZ232038A (en) 1991-06-25
DE69005833T2 (de) 1994-04-28
PT92801A (pt) 1990-07-31
MY106261A (en) 1995-04-29
NO178193C (no) 1996-02-07
ATE100096T1 (de) 1994-01-15
JPH02247174A (ja) 1990-10-02
EP0378357B1 (en) 1994-01-12
KR900011763A (ko) 1990-08-02
NO912696D0 (no) 1991-07-09
NO912696L (no) 1991-07-09
FI94247C (sv) 1995-08-10
IE61796B1 (en) 1994-11-30
ES2062318T3 (es) 1994-12-16
IE900074L (en) 1990-07-10
JPH0678337B2 (ja) 1994-10-05
CA2007651A1 (en) 1991-07-12
KR920006784B1 (ko) 1992-08-17
PT92801B (pt) 1995-12-29
AU4781790A (en) 1990-07-19
HUT58084A (en) 1992-01-28
DE69005833D1 (de) 1994-02-24
HU217072B (hu) 1999-11-29

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