ZA899451B - Catanospermine esters in the inhibition of tumor metastasis - Google Patents

Catanospermine esters in the inhibition of tumor metastasis

Info

Publication number
ZA899451B
ZA899451B ZA899451A ZA899451A ZA899451B ZA 899451 B ZA899451 B ZA 899451B ZA 899451 A ZA899451 A ZA 899451A ZA 899451 A ZA899451 A ZA 899451A ZA 899451 B ZA899451 B ZA 899451B
Authority
ZA
South Africa
Prior art keywords
inhibition
esters
catanospermine
tumor metastasis
administration
Prior art date
Application number
ZA899451A
Other languages
English (en)
Inventor
Sai Prasad Sunkara
Prasad Sunkara Sai
Paul Saiho Liu
Saiho Liu Paul
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA899451B publication Critical patent/ZA899451B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA899451A 1988-12-15 1989-12-11 Catanospermine esters in the inhibition of tumor metastasis ZA899451B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/284,510 US4952585A (en) 1988-12-15 1988-12-15 Castanospermine esters in the inhibition of tumor metastasis

Publications (1)

Publication Number Publication Date
ZA899451B true ZA899451B (en) 1990-09-26

Family

ID=23090466

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA899451A ZA899451B (en) 1988-12-15 1989-12-11 Catanospermine esters in the inhibition of tumor metastasis

Country Status (12)

Country Link
US (1) US4952585A (ko)
EP (1) EP0373663B1 (ko)
JP (1) JP2963476B2 (ko)
KR (1) KR0135278B1 (ko)
AT (1) ATE96320T1 (ko)
AU (1) AU621431B2 (ko)
DE (1) DE68910287T2 (ko)
DK (1) DK634689A (ko)
ES (1) ES2061912T3 (ko)
IE (1) IE62014B1 (ko)
PH (1) PH26024A (ko)
ZA (1) ZA899451B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US4970317A (en) * 1989-08-08 1990-11-13 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine esters
US5959111A (en) * 1997-05-22 1999-09-28 Hoechst Marion Roussel, Inc. Process for preparing 6-0-monoesters of castanospermine
EP0983270B1 (en) * 1997-05-22 2004-02-18 Aventis Pharmaceuticals Inc. Process for preparing 6-o-monoesters of castanospermine
US6013459A (en) * 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
WO2008088581A2 (en) * 2006-08-02 2008-07-24 United Therapeutics Corporation Liposome treatment of viral infections
US20090252785A1 (en) * 2008-03-26 2009-10-08 University Of Oxford Endoplasmic reticulum targeting liposomes
US8226684B2 (en) * 2008-12-22 2012-07-24 Ethicon, Inc. Surgical sutures having collapsible tissue anchoring protrusions and methods therefor
KR20120059447A (ko) * 2009-03-27 2012-06-08 더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드 콜레스테롤 수준 저하 리포좀
US20190046497A1 (en) * 2016-02-14 2019-02-14 Yeda Research And Development Co., Ltd. Methods of modulating protein exocytosis and uses of same in therapy
WO2018059215A1 (zh) 2016-09-29 2018-04-05 广州君赫生物科技有限公司 降低saicar累积的化合物及应用
AU2018253689B2 (en) 2017-04-20 2020-07-23 Geneheal Biotechnology Co., Ltd. Applications of spermidine and its derivative
CA3057206C (en) 2017-04-20 2022-11-01 Geneheal Biotechnology Co., Ltd. Applications of spermine and its derivative in preparation of antitumor drug

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792558A (en) * 1987-05-29 1988-12-20 Merrell Dow Pharmaceuticals Inc. Castanospermine for inhibiting tumor metastasis
CA1315276C (en) * 1987-07-02 1993-03-30 Paul S. Liu Castanospermine esters and glycosides
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
AU618838B2 (en) * 1988-08-10 1992-01-09 Praxis Pharmaceuticals, Inc. Use of castanospermine as an anti-inflammatory and immunosuppressant agent

Also Published As

Publication number Publication date
DK634689D0 (da) 1989-12-14
JP2963476B2 (ja) 1999-10-18
KR910011256A (ko) 1991-08-07
PH26024A (en) 1992-01-24
KR0135278B1 (ko) 1998-04-23
ATE96320T1 (de) 1993-11-15
EP0373663A2 (en) 1990-06-20
IE894009L (en) 1990-06-15
AU4670789A (en) 1990-06-21
US4952585A (en) 1990-08-28
AU621431B2 (en) 1992-03-12
EP0373663A3 (en) 1990-09-12
DE68910287D1 (de) 1993-12-02
EP0373663B1 (en) 1993-10-27
DE68910287T2 (de) 1994-03-10
ES2061912T3 (es) 1994-12-16
JPH02212427A (ja) 1990-08-23
DK634689A (da) 1990-06-16
IE62014B1 (en) 1994-12-14

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