ZA899356B - Novel compounds - Google Patents

Novel compounds

Info

Publication number
ZA899356B
ZA899356B ZA899356A ZA899356A ZA899356B ZA 899356 B ZA899356 B ZA 899356B ZA 899356 A ZA899356 A ZA 899356A ZA 899356 A ZA899356 A ZA 899356A ZA 899356 B ZA899356 B ZA 899356B
Authority
ZA
South Africa
Prior art keywords
alkyl
optionally substituted
phenyl
cycloalkyl
hydrogen
Prior art date
Application number
ZA899356A
Other languages
English (en)
Inventor
Ian Thomson Forbes
Thomson Forbes Ian
Roger Thomas Martin
Thomas Martin Roger
Mervyn Thompson
Thompson Mervyn
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA899356B publication Critical patent/ZA899356B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
ZA899356A 1988-12-09 1989-12-07 Novel compounds ZA899356B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888828806A GB8828806D0 (en) 1988-12-09 1988-12-09 Novel compounds

Publications (1)

Publication Number Publication Date
ZA899356B true ZA899356B (en) 1990-10-31

Family

ID=10648253

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA899356A ZA899356B (en) 1988-12-09 1989-12-07 Novel compounds

Country Status (12)

Country Link
US (1) US5079246A (fr)
EP (1) EP0372962B1 (fr)
JP (1) JPH02184687A (fr)
AT (1) ATE108792T1 (fr)
AU (1) AU629578B2 (fr)
CA (1) CA2004893A1 (fr)
DE (1) DE68916918T2 (fr)
DK (1) DK618389A (fr)
GB (1) GB8828806D0 (fr)
NZ (1) NZ231667A (fr)
PT (1) PT92524B (fr)
ZA (1) ZA899356B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW313589B (fr) * 1991-12-12 1997-08-21 Wacker Chemie Gmbh
US5856148A (en) * 1991-12-12 1999-01-05 Wacker Chemie Gmbh Materials and methods for biosynthesis of serine and serine-related products
GB9309179D0 (en) * 1993-05-05 1993-06-16 Smithkline Beecham Plc New use
JP2003535078A (ja) 2000-05-31 2003-11-25 アストラゼネカ アクチボラグ 血管損傷活性のあるインドール誘導体
US6956035B2 (en) * 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
AU2003214462A1 (en) 2002-04-03 2003-10-13 Astrazeneca Ab Indole derivatives having anti-angiogenetic activity
WO2005009398A2 (fr) * 2003-02-28 2005-02-03 Inotek Pharmaceuticals Corporation Derives de benzamide tetracyclique et leurs procedes d'utilisation
EA200601558A1 (ru) * 2004-02-26 2007-08-31 Инотек Фармасьютикалз Корпорейшн Производные изохинолинов и способы их использования
AU2005216530A1 (en) * 2004-02-26 2005-09-09 Inotek Pharmaceuticals Corporation Tetracyclic Lactam Derivatives and uses thereof
US20060019980A1 (en) * 2004-06-16 2006-01-26 Inotek Pharmaceutical, Corp. Methods for treating or preventing erectile dysfunction or urinary incontinence
WO2006093677A1 (fr) * 2005-02-25 2006-09-08 Inotek Pharmaceuticals Corporation Composes tetracycliques de sulfonamide et methodes d'utilisation desdits composes
JP2008531562A (ja) * 2005-02-25 2008-08-14 イノテック ファーマシューティカルズ コーポレイション 四環アミノ化合物および四環カルボキサミド化合物およびこれらの使用法
CA2597576A1 (fr) * 2005-02-25 2006-09-08 Inotek Pharmaceuticals Corporation Composes d'isoquinoline et procedes d'utilisation associes
CN101316592A (zh) * 2005-08-24 2008-12-03 伊诺泰克制药公司 茚并异喹啉酮类似物及其用法
JP2010520220A (ja) * 2007-02-28 2010-06-10 イノテック ファーマシューティカルズ コーポレイション インデノイソキノリノン類似体およびその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8600651D0 (en) * 1986-01-11 1986-02-19 Beecham Group Plc Compounds
GB8610980D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Heterocyclic fused tricyclic compounds

Also Published As

Publication number Publication date
DK618389A (da) 1990-06-10
CA2004893A1 (fr) 1990-06-09
DE68916918D1 (de) 1994-08-25
JPH02184687A (ja) 1990-07-19
EP0372962A3 (fr) 1991-07-31
ATE108792T1 (de) 1994-08-15
AU4596089A (en) 1990-06-14
NZ231667A (en) 1992-11-25
US5079246A (en) 1992-01-07
EP0372962A2 (fr) 1990-06-13
GB8828806D0 (en) 1989-01-18
AU629578B2 (en) 1992-10-08
DE68916918T2 (de) 1994-11-03
PT92524B (pt) 1995-08-09
PT92524A (pt) 1990-06-29
DK618389D0 (da) 1989-12-07
EP0372962B1 (fr) 1994-07-20

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