ZA896490B - One-step in situ hybridization assay - Google Patents
One-step in situ hybridization assayInfo
- Publication number
- ZA896490B ZA896490B ZA896490A ZA896490A ZA896490B ZA 896490 B ZA896490 B ZA 896490B ZA 896490 A ZA896490 A ZA 896490A ZA 896490 A ZA896490 A ZA 896490A ZA 896490 B ZA896490 B ZA 896490B
- Authority
- ZA
- South Africa
- Prior art keywords
- situ hybridization
- hybridization assay
- assay
- copies
- quantitative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Materials For Medical Uses (AREA)
- Inorganic Insulating Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Television Systems (AREA)
- Stereo-Broadcasting Methods (AREA)
- Valve Device For Special Equipments (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23910688A | 1988-08-31 | 1988-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA896490B true ZA896490B (en) | 1990-06-27 |
Family
ID=22900643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA896490A ZA896490B (en) | 1988-08-31 | 1989-08-25 | One-step in situ hybridization assay |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP0432221B1 (xx) |
| JP (1) | JPH04502552A (xx) |
| AT (1) | ATE153705T1 (xx) |
| AU (1) | AU636854B2 (xx) |
| DE (1) | DE68928080T2 (xx) |
| DK (1) | DK34191A (xx) |
| FI (1) | FI910957A0 (xx) |
| IL (1) | IL91405A (xx) |
| NZ (1) | NZ230389A (xx) |
| PT (1) | PT91589B (xx) |
| WO (1) | WO1990002173A1 (xx) |
| ZA (1) | ZA896490B (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985549A (en) * | 1985-10-22 | 1999-11-16 | University Of Massachusetts | Non-isotopic in-situ hybridization method for detection of nucleic acids |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| JPH04502552A (ja) * | 1988-08-31 | 1992-05-14 | アプロジェネックス，インク | ワン―ステップのインシチュハイブリッド形成分析法 |
| US6242184B1 (en) | 1988-10-18 | 2001-06-05 | University Of Massachusetts | In-situ hybridization of single-copy and multiple-copy nucleic acid sequences |
| US6203977B1 (en) | 1988-11-15 | 2001-03-20 | Yale University | Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization |
| JPH04505556A (ja) * | 1989-03-07 | 1992-10-01 | シンジェン，インコーポレイテッド | 細胞の検出または分離のための浮遊状態におけるインシトゥハイブリッド形成法 |
| IL99025A0 (en) * | 1990-08-15 | 1992-07-15 | Astra Ab | Novel process for the detection of pathogens using dna probes |
| US5629147A (en) * | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
| EP0662152A1 (en) * | 1992-07-17 | 1995-07-12 | Aprogenex, Inc. | Enriching and identyfying fetal cells in maternal blood for in situ hybridization |
| US5521061A (en) * | 1992-07-17 | 1996-05-28 | Aprogenex, Inc. | Enhancement of probe signal in nucleic acid-mediated in-situ hybridization studies |
| US6107033A (en) * | 1995-07-28 | 2000-08-22 | Rijksuniversiteit Groningen | Methods and materials for determining relative abundance of microorganisms in mixed populations |
| CA2250105A1 (en) * | 1996-04-19 | 1997-10-30 | Nycomed Amersham Plc | High volume in-situ mrna hybridization method for the quantification and discovery of disease specific genes |
| ES2344873T3 (es) * | 1998-05-18 | 2010-09-08 | Igenex, Inc. | Procedimiento de hibridacion in situ para detectar un acido nucleico diana. |
| JP4557347B2 (ja) * | 2000-01-30 | 2010-10-06 | 株式会社カイノス | 特定の塩基配列を有する標的核酸の検出またはその核酸量の測定方法 |
| US20040115692A1 (en) * | 2000-04-03 | 2004-06-17 | Cytyc Corporation | Methods, compositions and apparatuses for detecting a target in a preservative solution |
| US9212390B2 (en) | 2010-04-30 | 2015-12-15 | Exiqon A/S | In situ hybridization method and buffer |
| CN115768780A (zh) * | 2020-04-07 | 2023-03-07 | 领先细胞医疗诊断有限公司 | 通过原位杂交检测靶核酸的方法及其试剂盒 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04502552A (ja) * | 1988-08-31 | 1992-05-14 | アプロジェネックス，インク | ワン―ステップのインシチュハイブリッド形成分析法 |
| JPH04505556A (ja) * | 1989-03-07 | 1992-10-01 | シンジェン，インコーポレイテッド | 細胞の検出または分離のための浮遊状態におけるインシトゥハイブリッド形成法 |
-
1989
- 1989-08-18 JP JP1510636A patent/JPH04502552A/ja active Pending
- 1989-08-18 DE DE68928080T patent/DE68928080T2/de not_active Expired - Lifetime
- 1989-08-18 AT AT89911504T patent/ATE153705T1/de not_active IP Right Cessation
- 1989-08-18 AU AU43439/89A patent/AU636854B2/en not_active Ceased
- 1989-08-18 EP EP89911504A patent/EP0432221B1/en not_active Expired - Lifetime
- 1989-08-18 WO PCT/US1989/003580 patent/WO1990002173A1/en active IP Right Grant
- 1989-08-22 NZ NZ230389A patent/NZ230389A/xx unknown
- 1989-08-24 IL IL9140589A patent/IL91405A/en not_active IP Right Cessation
- 1989-08-25 ZA ZA896490A patent/ZA896490B/xx unknown
- 1989-08-30 PT PT91589A patent/PT91589B/pt not_active IP Right Cessation
- 1989-08-31 EP EP19890308850 patent/EP0357436A3/en not_active Withdrawn
-
1991
- 1991-02-27 FI FI910957A patent/FI910957A0/fi not_active Application Discontinuation
- 1991-02-27 DK DK034191A patent/DK34191A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT91589A (pt) | 1990-03-08 |
| AU636854B2 (en) | 1993-05-13 |
| PT91589B (pt) | 1995-08-09 |
| EP0432221B1 (en) | 1997-05-28 |
| EP0357436A2 (en) | 1990-03-07 |
| EP0357436A3 (en) | 1991-06-12 |
| DE68928080T2 (de) | 1998-01-15 |
| EP0432221A4 (en) | 1992-01-15 |
| JPH04502552A (ja) | 1992-05-14 |
| EP0432221A1 (en) | 1991-06-19 |
| IL91405A (en) | 1996-03-31 |
| AU4343989A (en) | 1990-03-23 |
| FI910957A0 (fi) | 1991-02-27 |
| WO1990002173A1 (en) | 1990-03-08 |
| NZ230389A (en) | 1991-11-26 |
| DK34191D0 (da) | 1991-02-27 |
| DK34191A (da) | 1991-04-30 |
| DE68928080D1 (de) | 1997-07-03 |
| IL91405A0 (en) | 1990-04-29 |
| ATE153705T1 (de) | 1997-06-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL91405A0 (en) | One-step in situ hybridization assay | |
| FI910958A0 (fi) | Manuell in situ- -hybridisationsbestaemning. | |
| EP0288082A3 (en) | A tumor specific assay for ca125 ovarian cancer antigen | |
| NO870613D0 (no) | Deteksjon av mikroorganismer i en proeve inneholdende nukleinsyre. | |
| DE58905607D1 (de) | System zum Erkennen des Starts und des Anflugs von Objekten. | |
| AU4269589A (en) | Assay and sensing means for determining analyte | |
| HK1033773A1 (en) | An assay for detecting anti-hepatitis c virus and the kit therefor. | |
| ES8700270A1 (es) | Un metodo para producir nucleotidos. | |
| EP0662518A3 (en) | Nucleic acid probe for detection of HPV transcripts. | |
| DE3063025D1 (en) | Compositions, methods and elements for detecting or assaying peroxidatively active substances | |
| DE3789847T2 (de) | Vorrichtung zum Zuführen und Überwachen von Streifen. | |
| AU6643290A (en) | Methods and reagents to detect and characterize norwalk and related viruses | |
| DK559488D0 (da) | Faste kornformige katalysatorer, fremgangsmaade til deres fremstilling samt deres anvendelse | |
| DE3877986D1 (de) | System zum erkennen des klopfens. | |
| EP0355989A3 (en) | Dna and rna probes, methods and kits for the detection of salmonella | |
| ZA865767B (en) | Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present | |
| DE68906167T2 (de) | Zusammensetzung zur erkennung von paradontalen krankheiten. | |
| WO1993002217A3 (fr) | Sondes oligonucleotidiques pour le typage et la detection des papillomavirus humains | |
| AU7397487A (en) | Microchemiluminescent assay for detection and quantification of oxidative injury to cells | |
| Rysavy | BIOLOGICAL SYSTEMS AND ASSESSMENT OF THEIR EFFECTS ON POLYMERS | |
| DE3678294D1 (de) | Vorrichtung zur durchfuehrung zellbiologischer versuche. | |
| AU6189498A (en) | Biotin-labelled DNA by polymerase chain reaction and detection thereof | |
| IL119895A (en) | Electrochemiluminecent assay for detecting the presence in a sample of microorganisms | |
| DE68907296D1 (de) | Enzymatischer nachweis von einwertigen anionen. | |
| NO301890B1 (no) | Fremgangsmåte for forsterkning av minst en spesifikk nukleinsyre-sekvens samt anvendelse av fremgangsmåten |