ZA895969B - Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- ZA895969B ZA895969B ZA895969A ZA895969A ZA895969B ZA 895969 B ZA895969 B ZA 895969B ZA 895969 A ZA895969 A ZA 895969A ZA 895969 A ZA895969 A ZA 895969A ZA 895969 B ZA895969 B ZA 895969B
- Authority
- ZA
- South Africa
- Prior art keywords
- processes
- pharmaceutical compositions
- alkoxy
- compositions containing
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3826846A DE3826846A1 (de) | 1988-08-06 | 1988-08-06 | Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA895969B true ZA895969B (en) | 1990-05-30 |
Family
ID=6360419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA895969A ZA895969B (en) | 1988-08-06 | 1989-08-04 | Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing them |
Country Status (18)
Country | Link |
---|---|
US (2) | US5185352A (ja) |
EP (2) | EP0427765B1 (ja) |
JP (1) | JP2878361B2 (ja) |
KR (1) | KR920006779B1 (ja) |
CN (1) | CN1040193A (ja) |
AT (1) | ATE188469T1 (ja) |
AU (1) | AU627766B2 (ja) |
CA (1) | CA1340608C (ja) |
DD (1) | DD284003A5 (ja) |
DE (2) | DE3826846A1 (ja) |
DK (1) | DK174097B1 (ja) |
ES (1) | ES2144391T3 (ja) |
GR (1) | GR3033072T3 (ja) |
HU (1) | HUT56545A (ja) |
NO (1) | NO177785C (ja) |
PT (1) | PT91351B (ja) |
WO (1) | WO1990001477A1 (ja) |
ZA (1) | ZA895969B (ja) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1283404C (en) * | 1986-07-01 | 1991-04-23 | Shigeru Sanai | Cephalosporin compounds, processes for their preparation and antibacterial agents |
DE3826846A1 (de) * | 1988-08-06 | 1990-02-08 | Goedecke Ag | Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
US5674883A (en) * | 1992-02-07 | 1997-10-07 | Roussel Uclaf | Derivatives of pyridone, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them |
FR2687674B1 (fr) * | 1992-02-07 | 1995-05-19 | Roussel Uclaf | Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
DE4243321A1 (de) * | 1992-12-21 | 1994-06-23 | Goedecke Ag | Aminosäurederivate von Heterocyclen als PKC-Inhibitoren |
US6046219A (en) * | 1995-01-20 | 2000-04-04 | Cornell Research Foundation, Inc. | Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation |
US5849587A (en) * | 1995-06-09 | 1998-12-15 | Cornell Research Foundation, Inc. | Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells |
GB2321455A (en) * | 1997-01-24 | 1998-07-29 | Norsk Hydro As | Lipophilic derivatives of biologically active compounds |
WO2000033857A1 (en) * | 1998-12-07 | 2000-06-15 | Ecosmart Technologies, Inc. | Cancer treatment composition and method using natural plant essential oils |
US6716838B1 (en) | 1999-05-19 | 2004-04-06 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents |
US6750342B1 (en) | 1999-05-19 | 2004-06-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6906068B1 (en) | 1999-05-19 | 2005-06-14 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4 - triazinones useful as anticoagulants |
US6653316B1 (en) | 1999-05-19 | 2003-11-25 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade |
US6867217B1 (en) | 1999-05-19 | 2005-03-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
US7015230B1 (en) | 1999-05-19 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade |
US6664255B1 (en) | 1999-05-19 | 2003-12-16 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade |
US6852761B2 (en) | 2000-03-13 | 2005-02-08 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade |
JP2004505013A (ja) * | 2000-04-05 | 2004-02-19 | ファルマシア・コーポレーション | 凝固カスケードを選択的に阻害するのに有用な多環式アリール及びヘテロアリール置換4−ピリドン類 |
WO2001077097A2 (en) | 2000-04-05 | 2001-10-18 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade |
US7119094B1 (en) | 2000-11-20 | 2006-10-10 | Warner-Lambert Company | Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade |
US7015223B1 (en) | 2000-11-20 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade |
EP1351686A2 (en) | 2000-11-20 | 2003-10-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade |
MXPA04003170A (es) | 2001-10-03 | 2004-07-08 | Pharmacia Corp | Compuestos policiclicos, sustituidos, provisto de 5 miembros, utiles para la inhibicion selectiva de la cascada de coagulacion. |
US6969715B2 (en) | 2001-10-03 | 2005-11-29 | Pharmacia Corporation | 6-membered heterocyclic compounds useful for selective inhibition of the coagulation cascade |
US8026261B2 (en) | 2007-03-28 | 2011-09-27 | Apotex Technologies Inc. | Fluorinated derivatives of deferiprone |
DK2268282T3 (en) | 2008-04-25 | 2014-11-24 | Apotex Technologies Inc | Liquid formulation of deferiprone with pleasant taste |
WO2010127346A1 (en) | 2009-05-01 | 2010-11-04 | Eurand, Inc. | Orally disintegrating tablet compositions comprising combinations of non-opioid and opioid analgesics |
SI2448922T1 (sl) | 2009-07-03 | 2014-12-31 | Apotex Technologies Inc. | Fluorirani derivati 3-hidroksipiridin-4-onov |
PL3287443T3 (pl) | 2015-04-24 | 2022-02-21 | Shionogi & Co., Ltd | 6-członowa pochodna heterocykliczna i kompozycja farmaceutyczna ją zawierająca |
JP6692113B2 (ja) * | 2016-10-21 | 2020-05-13 | 塩野義製薬株式会社 | 6員複素環誘導体を含有する医薬組成物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA554715A (en) * | 1958-03-18 | Boesch Roger | Ethers and thioethers and processes for their preparation | |
US2965641A (en) * | 1959-07-06 | 1960-12-20 | Searle & Co | Derivatives of 1-(2-aminoethyl)-5-alkoxy-4-pyridones |
CA978958A (en) * | 1971-10-04 | 1975-12-02 | Haydn W.R. Williams | Substituted pyranones and -pyridones and process of manufacture |
JPS59110674A (ja) * | 1982-12-16 | 1984-06-26 | Ss Pharmaceut Co Ltd | ピリジン誘導体及びその製造法 |
JPS59110675A (ja) * | 1982-12-16 | 1984-06-26 | Ss Pharmaceut Co Ltd | ピリジン誘導体及びその製造方法 |
GB8308055D0 (en) * | 1983-03-24 | 1983-05-05 | Hider R C | Pharmaceutical compositions |
CA1283404C (en) * | 1986-07-01 | 1991-04-23 | Shigeru Sanai | Cephalosporin compounds, processes for their preparation and antibacterial agents |
DE3826846A1 (de) * | 1988-08-06 | 1990-02-08 | Goedecke Ag | Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
-
1988
- 1988-08-06 DE DE3826846A patent/DE3826846A1/de not_active Ceased
-
1989
- 1989-08-02 PT PT91351A patent/PT91351B/pt not_active IP Right Cessation
- 1989-08-02 DD DD89331409A patent/DD284003A5/de not_active IP Right Cessation
- 1989-08-04 JP JP1508466A patent/JP2878361B2/ja not_active Expired - Fee Related
- 1989-08-04 CA CA000607563A patent/CA1340608C/en not_active Expired - Fee Related
- 1989-08-04 HU HU894581A patent/HUT56545A/hu unknown
- 1989-08-04 EP EP89908987A patent/EP0427765B1/de not_active Expired - Lifetime
- 1989-08-04 ZA ZA895969A patent/ZA895969B/xx unknown
- 1989-08-04 EP EP89114477A patent/EP0354495A1/de active Pending
- 1989-08-04 US US07/640,407 patent/US5185352A/en not_active Expired - Lifetime
- 1989-08-04 AU AU40489/89A patent/AU627766B2/en not_active Ceased
- 1989-08-04 KR KR1019900700696A patent/KR920006779B1/ko not_active IP Right Cessation
- 1989-08-04 ES ES89908987T patent/ES2144391T3/es not_active Expired - Lifetime
- 1989-08-04 WO PCT/EP1989/000927 patent/WO1990001477A1/de active IP Right Grant
- 1989-08-04 DE DE58909865T patent/DE58909865D1/de not_active Expired - Fee Related
- 1989-08-04 AT AT89908987T patent/ATE188469T1/de not_active IP Right Cessation
- 1989-08-05 CN CN89105574A patent/CN1040193A/zh active Pending
-
1991
- 1991-01-23 DK DK199100113A patent/DK174097B1/da not_active IP Right Cessation
- 1991-02-05 NO NO910444A patent/NO177785C/no unknown
-
1992
- 1992-10-07 US US07/957,937 patent/US5322844A/en not_active Expired - Fee Related
-
2000
- 2000-03-27 GR GR20000400761T patent/GR3033072T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DD284003A5 (de) | 1990-10-31 |
EP0427765B1 (de) | 2000-01-05 |
DE58909865D1 (de) | 2000-02-10 |
EP0354495A1 (de) | 1990-02-14 |
US5185352A (en) | 1993-02-09 |
AU627766B2 (en) | 1992-09-03 |
PT91351A (pt) | 1990-03-08 |
CA1340608C (en) | 1999-06-22 |
PT91351B (pt) | 1997-01-31 |
DK174097B1 (da) | 2002-06-10 |
JP2878361B2 (ja) | 1999-04-05 |
KR900701755A (ko) | 1990-12-04 |
ATE188469T1 (de) | 2000-01-15 |
EP0427765A1 (de) | 1991-05-22 |
HUT56545A (en) | 1991-09-30 |
NO177785C (no) | 1995-11-22 |
NO910444D0 (no) | 1991-02-05 |
WO1990001477A1 (de) | 1990-02-22 |
NO177785B (no) | 1995-08-14 |
NO910444L (no) | 1991-02-05 |
US5322844A (en) | 1994-06-21 |
DK11391D0 (da) | 1991-01-23 |
ES2144391T3 (es) | 2000-06-16 |
DK11391A (da) | 1991-01-23 |
DE3826846A1 (de) | 1990-02-08 |
HU894581D0 (en) | 1991-07-29 |
JPH04500958A (ja) | 1992-02-20 |
CN1040193A (zh) | 1990-03-07 |
KR920006779B1 (ko) | 1992-08-17 |
GR3033072T3 (en) | 2000-08-31 |
AU4048989A (en) | 1990-03-05 |
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