ZA895460B - Novel proteins - Google Patents

Novel proteins

Info

Publication number
ZA895460B
ZA895460B ZA895460A ZA895460A ZA895460B ZA 895460 B ZA895460 B ZA 895460B ZA 895460 A ZA895460 A ZA 895460A ZA 895460 A ZA895460 A ZA 895460A ZA 895460 B ZA895460 B ZA 895460B
Authority
ZA
South Africa
Prior art keywords
novel proteins
proteins
novel
Prior art date
Application number
ZA895460A
Other languages
English (en)
Inventor
Andrew Wallace
Wallace Andrew
Stanley Dennis
Dennis Stanley
Jan Hofsteenge
Hofsteenge Jan
Stuart R Stone
R Stone Stuart
Original Assignee
Ciba Geigy Ag
Ucp Gen Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag, Ucp Gen Pharma Ag filed Critical Ciba Geigy Ag
Publication of ZA895460B publication Critical patent/ZA895460B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA895460A 1988-07-19 1989-07-18 Novel proteins ZA895460B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817160A GB8817160D0 (en) 1988-07-19 1988-07-19 Novel proteins

Publications (1)

Publication Number Publication Date
ZA895460B true ZA895460B (en) 1990-02-28

Family

ID=10640714

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895460A ZA895460B (en) 1988-07-19 1989-07-18 Novel proteins

Country Status (13)

Country Link
EP (1) EP0352228A3 (fr)
JP (1) JPH02117694A (fr)
KR (1) KR900001848A (fr)
AU (1) AU3804589A (fr)
DD (1) DD284045A5 (fr)
DK (1) DK355189A (fr)
FI (1) FI893451A (fr)
GB (1) GB8817160D0 (fr)
HU (1) HUT51671A (fr)
IL (1) IL91003A0 (fr)
NO (1) NO892949L (fr)
PT (1) PT91190A (fr)
ZA (1) ZA895460B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614121B2 (en) * 1988-05-04 1991-08-22 Novartis Ag Improvements in the production of polypeptides
DE4009268A1 (de) * 1990-03-22 1991-09-26 Consortium Elektrochem Ind Sekretion von hirudinderivaten
GB9010552D0 (en) * 1990-05-10 1990-07-04 Erba Carlo Spa Method for the recombinant production of hirudins and novel hirudins
US6060451A (en) * 1990-06-15 2000-05-09 The National Research Council Of Canada Thrombin inhibitors based on the amino acid sequence of hirudin
US6514730B1 (en) 1991-03-21 2003-02-04 Consortium für elektrochemische Industrie GmbH Secretion of hirudin derivatives
US5837808A (en) * 1991-08-20 1998-11-17 Baxter International Inc. Analogs of hirudin
US6274553B1 (en) 1997-01-20 2001-08-14 Japan Energy Corporation Method for stabilizing peptides and freeze-dried medicinal compositions containing peptides obtained by using the method
EP1597279A1 (fr) * 2003-02-27 2005-11-23 National Research Council Of Canada Inhibiteurs peptidiques de thrombine en tant qu'anticoagulants puissants
US7795205B2 (en) 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE64956T1 (de) * 1984-06-14 1991-07-15 Ciba Geigy Ag Verfahren zur herstellung von thrombininhibitoren.
EP0209061B1 (fr) * 1985-07-17 1994-01-12 Hoechst Aktiengesellschaft Peptides à activité anticoagulante, leur procédé de préparation, d'obtention, leur application et les agents les contenant
FR2607517B2 (fr) * 1986-12-01 1989-12-22 Transgene Sa Vecteurs d'expression de variants de l'hirudine dans les levures, procede et produit obtenu

Also Published As

Publication number Publication date
PT91190A (pt) 1990-02-08
HUT51671A (en) 1990-05-28
JPH02117694A (ja) 1990-05-02
IL91003A0 (en) 1990-02-09
FI893451A0 (fi) 1989-07-17
FI893451A (fi) 1990-01-20
DK355189D0 (da) 1989-07-18
NO892949D0 (no) 1989-07-18
NO892949L (no) 1990-01-22
GB8817160D0 (en) 1988-08-24
EP0352228A2 (fr) 1990-01-24
AU3804589A (en) 1990-01-25
DK355189A (da) 1990-01-20
EP0352228A3 (fr) 1990-07-11
DD284045A5 (de) 1990-10-31
KR900001848A (ko) 1990-02-27

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