ZA893675B - 2-hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines - Google Patents
2-hydroxy-propanoic acid acyclic alkyl esters for benzothiazepinesInfo
- Publication number
- ZA893675B ZA893675B ZA893675A ZA893675A ZA893675B ZA 893675 B ZA893675 B ZA 893675B ZA 893675 A ZA893675 A ZA 893675A ZA 893675 A ZA893675 A ZA 893675A ZA 893675 B ZA893675 B ZA 893675B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzothiazepines
- hydroxy
- propanoic acid
- alkyl esters
- acyclic alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/195,709 US4908469A (en) | 1988-05-18 | 1988-05-18 | 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA893675B true ZA893675B (en) | 1990-01-31 |
Family
ID=22722456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA893675A ZA893675B (en) | 1988-05-18 | 1989-05-17 | 2-hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines |
Country Status (5)
Country | Link |
---|---|
US (1) | US4908469A (de) |
EP (1) | EP0342902A3 (de) |
JP (1) | JPH0217168A (de) |
AU (1) | AU3491389A (de) |
ZA (1) | ZA893675B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8801311A (nl) * | 1988-05-20 | 1989-12-18 | Stamicarbon | Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem. |
IT1232306B (it) * | 1989-07-27 | 1992-01-28 | Zambon Spa | Processo di risoluzione di intermedi utili per la preparazione del diltiazem |
JPH0415445U (de) * | 1990-05-25 | 1992-02-07 | ||
FI93741C (fi) * | 1993-03-24 | 1995-05-26 | Orion Yhtymae Oy | Menetelmä optisesti puhtaitten (2S,3S)- ja (2R,3R)-threo-alkyyli-2-hydroksi-3-(4-metoksifenyyli)-3-(2-X-fenyylitio)propionaattien tai vastaavien asyloitujen yhdisteiden valmistamiseksi |
FI97725C (fi) * | 1995-02-17 | 1997-02-10 | Orion Yhtymae Oy | Menetelmä diltiatseemin valmistamiseksi |
DE19541717A1 (de) * | 1995-11-09 | 1997-05-15 | Bayer Ag | Verfahren zur Herstellung von (2RS, 3RS)-3-(2'Aminophenylthio)-2-hydroxy-3-(4"-methoxyphenyl)-propionsäuremethylester |
IL123352A0 (en) | 1997-02-27 | 1998-09-24 | Tanabe Seiyaku Co | Process for preparing an optically active trans-3-substituted glycidic acid ester |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
EP0059335B1 (de) * | 1981-02-27 | 1985-05-15 | Tanabe Seiyaku Co., Ltd. | Verfahren zur Herstellung von threo-2-Hydroxy-3-(-methoxyphenyl)-3-(2-nitrophenylthio)-propionsäureestern |
SE449611B (sv) * | 1982-07-09 | 1987-05-11 | Tanabe Seiyaku Co | Sett att framstella 1,5-bensotiazepinderivat |
IT1152721B (it) * | 1982-10-15 | 1987-01-07 | Luso Farmaco Inst | Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico |
US4552695A (en) * | 1983-04-21 | 1985-11-12 | Shionogi & Co., Ltd. | Process for production of diltiazem hydrochloride |
US4567175A (en) * | 1983-06-03 | 1986-01-28 | Tanabe Seiyaku Co., Ltd. | 8-Chloro-1,5-benzothiazepine derivatives |
JPS6013776A (ja) * | 1983-07-05 | 1985-01-24 | Sawai Seiyaku Kk | 光学活性3−(p−アルコキシフエニル)グリシツド酸誘導体の製造法 |
JPS6013775A (ja) * | 1983-07-05 | 1985-01-24 | Sawai Seiyaku Kk | 光学活性3−(p−アルコキシフエニル)グリシツド酸アルカリ金属塩の製造法 |
JPS6078973A (ja) * | 1983-10-07 | 1985-05-04 | Toshin Chem Kk | 1,5−ベンゾチアゼピン誘導体の製法 |
JPS61145160A (ja) * | 1984-12-20 | 1986-07-02 | Nippon Chemiphar Co Ltd | 光学活性なプロピオン酸誘導体の製造法 |
JPS61268663A (ja) * | 1985-05-22 | 1986-11-28 | Fuji Kagaku Kogyo Kk | 光学活性な2−ヒドロキシ−3,3−ジ置換プロピオン酸の製造方法 |
-
1988
- 1988-05-18 US US07/195,709 patent/US4908469A/en not_active Expired - Fee Related
-
1989
- 1989-05-15 EP EP19890304893 patent/EP0342902A3/de not_active Withdrawn
- 1989-05-17 ZA ZA893675A patent/ZA893675B/xx unknown
- 1989-05-18 JP JP1125451A patent/JPH0217168A/ja active Pending
- 1989-05-18 AU AU34913/89A patent/AU3491389A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JPH0217168A (ja) | 1990-01-22 |
AU3491389A (en) | 1989-11-23 |
EP0342902A2 (de) | 1989-11-23 |
US4908469B1 (de) | 1992-06-02 |
EP0342902A3 (de) | 1991-01-30 |
US4908469A (en) | 1990-03-13 |
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