ZA891997B - Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments - Google Patents
Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicamentsInfo
- Publication number
- ZA891997B ZA891997B ZA891997A ZA891997A ZA891997B ZA 891997 B ZA891997 B ZA 891997B ZA 891997 A ZA891997 A ZA 891997A ZA 891997 A ZA891997 A ZA 891997A ZA 891997 B ZA891997 B ZA 891997B
- Authority
- ZA
- South Africa
- Prior art keywords
- clyclic
- arylpiperazinylalkoxy
- imides
- medicaments
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/169,550 US4780466A (en) | 1988-03-17 | 1988-03-17 | Arylpiperazinylalkoxy derivatives of cyclic imides |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA891997B true ZA891997B (en) | 1989-10-25 |
Family
ID=22616166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA891997A ZA891997B (en) | 1988-03-17 | 1989-03-16 | Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments |
Country Status (14)
Country | Link |
---|---|
US (1) | US4780466A (xx) |
EP (1) | EP0333137A1 (xx) |
JP (1) | JPH024771A (xx) |
KR (1) | KR890014522A (xx) |
AU (1) | AU611780B2 (xx) |
DK (1) | DK128889A (xx) |
FI (1) | FI891222A (xx) |
HU (1) | HU203233B (xx) |
IL (1) | IL89621A0 (xx) |
NO (1) | NO891151L (xx) |
NZ (1) | NZ228339A (xx) |
PH (1) | PH26669A (xx) |
PT (1) | PT90017A (xx) |
ZA (1) | ZA891997B (xx) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5312840A (en) * | 1986-07-10 | 1994-05-17 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education | Substituted guanidines having high binding to the sigma receptor and the use thereof |
US5502255A (en) * | 1986-07-10 | 1996-03-26 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Substituted guanidines having high binding to the sigma receptor and the use thereof |
US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
US5561128A (en) * | 1989-05-19 | 1996-10-01 | Hoechst-Roussel Pharmaceuticals, Inc. | N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility |
US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
ES2019228A6 (es) * | 1990-02-13 | 1991-06-01 | Espanola Prod Quimicos | Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona. |
JPH05508836A (ja) * | 1990-05-25 | 1993-12-09 | オレゴン州 | シグマ受容体に対して高い結合性を有する置換グアニジンおよびその使用 |
GB9202915D0 (en) * | 1992-02-12 | 1992-03-25 | Wellcome Found | Chemical compounds |
US5272148A (en) * | 1992-09-09 | 1993-12-21 | Hoechst-Roussel Pharmaceuticals Incorporated | Heteroarenylpiperazines |
EP0635506A4 (en) * | 1993-02-04 | 1995-04-12 | Meiji Seika Co | CONNECTION WITH ANTIPSYCHOTIC EFFECT. |
DE4333249A1 (de) * | 1993-09-30 | 1995-04-06 | Hoechst Schering Agrevo Gmbh | Neue Mischungen aus Herbiziden und Antidots |
DE69618050T2 (de) * | 1995-03-17 | 2002-07-11 | Aventis Pharmaceuticals Inc., Cincinnati | Substituierte Benzylthienylpiperazine, ihre Anwendung als Arzneimittel und Verfahren für ihre Herstellung |
US6025355A (en) * | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
US6756389B2 (en) * | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1405319A (fr) * | 1964-05-26 | 1965-07-09 | Ile Auguil Soc Civ | Procédé de préparation de l'(oxo-2 pyrrolidino-1)-1 (pyrrolidino-1)-4 butyne-2, et nouveaux sels de ce composé |
JPS51125389A (en) * | 1975-04-09 | 1976-11-01 | Yoshitomi Pharmaceut Ind Ltd | A process for preparing heterocyclic compovnds |
DE2658762A1 (de) * | 1976-12-24 | 1978-06-29 | Hoechst Ag | Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4367335A (en) * | 1981-08-03 | 1983-01-04 | Mead Johnson & Company | Thiazolidinylalkylene piperazine derivatives |
US4423049A (en) * | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
US4620006A (en) * | 1982-08-11 | 1986-10-28 | Eastman Kodak Company | Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines |
US4656173A (en) * | 1985-04-24 | 1987-04-07 | Bristol-Myers Company | Antipsychotic benzisothiazole S-oxide compound |
CA1278792C (en) * | 1985-05-06 | 1991-01-08 | Joseph P. Yevich | Antipsychotic fused-ring pyridinylpiperazine derivatives |
US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
-
1988
- 1988-03-17 US US07/169,550 patent/US4780466A/en not_active Expired - Fee Related
-
1989
- 1989-03-14 EP EP89104523A patent/EP0333137A1/en not_active Withdrawn
- 1989-03-15 FI FI891222A patent/FI891222A/fi not_active Application Discontinuation
- 1989-03-15 NZ NZ228339A patent/NZ228339A/en unknown
- 1989-03-15 IL IL89621A patent/IL89621A0/xx unknown
- 1989-03-15 PH PH38331A patent/PH26669A/en unknown
- 1989-03-16 AU AU31376/89A patent/AU611780B2/en not_active Ceased
- 1989-03-16 KR KR1019890003249A patent/KR890014522A/ko not_active Application Discontinuation
- 1989-03-16 DK DK128889A patent/DK128889A/da not_active Application Discontinuation
- 1989-03-16 PT PT90017A patent/PT90017A/pt not_active Application Discontinuation
- 1989-03-16 ZA ZA891997A patent/ZA891997B/xx unknown
- 1989-03-16 JP JP1062344A patent/JPH024771A/ja active Pending
- 1989-03-16 NO NO89891151A patent/NO891151L/no unknown
- 1989-03-17 HU HU891260A patent/HU203233B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ228339A (en) | 1991-07-26 |
EP0333137A1 (en) | 1989-09-20 |
FI891222A0 (fi) | 1989-03-15 |
PT90017A (pt) | 1989-11-10 |
AU611780B2 (en) | 1991-06-20 |
IL89621A0 (en) | 1989-09-10 |
DK128889A (da) | 1989-09-18 |
JPH024771A (ja) | 1990-01-09 |
US4780466A (en) | 1988-10-25 |
PH26669A (en) | 1992-09-15 |
HUT49874A (en) | 1989-11-28 |
KR890014522A (ko) | 1989-10-24 |
HU203233B (en) | 1991-06-28 |
DK128889D0 (da) | 1989-03-16 |
NO891151L (no) | 1989-09-18 |
NO891151D0 (no) | 1989-03-16 |
AU3137689A (en) | 1989-09-21 |
FI891222A (fi) | 1989-09-18 |
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