ZA891997B - Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments - Google Patents

Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments

Info

Publication number
ZA891997B
ZA891997B ZA891997A ZA891997A ZA891997B ZA 891997 B ZA891997 B ZA 891997B ZA 891997 A ZA891997 A ZA 891997A ZA 891997 A ZA891997 A ZA 891997A ZA 891997 B ZA891997 B ZA 891997B
Authority
ZA
South Africa
Prior art keywords
clyclic
arylpiperazinylalkoxy
imides
medicaments
derivatives
Prior art date
Application number
ZA891997A
Other languages
English (en)
Inventor
Nicholas Joseph Hrib
Joseph Hrib Nicholas
John Gerard Jurcak
Gerard Jurcak John
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA891997B publication Critical patent/ZA891997B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA891997A 1988-03-17 1989-03-16 Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments ZA891997B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/169,550 US4780466A (en) 1988-03-17 1988-03-17 Arylpiperazinylalkoxy derivatives of cyclic imides

Publications (1)

Publication Number Publication Date
ZA891997B true ZA891997B (en) 1989-10-25

Family

ID=22616166

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891997A ZA891997B (en) 1988-03-17 1989-03-16 Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments

Country Status (14)

Country Link
US (1) US4780466A (da)
EP (1) EP0333137A1 (da)
JP (1) JPH024771A (da)
KR (1) KR890014522A (da)
AU (1) AU611780B2 (da)
DK (1) DK128889A (da)
FI (1) FI891222A (da)
HU (1) HU203233B (da)
IL (1) IL89621A0 (da)
NO (1) NO891151L (da)
NZ (1) NZ228339A (da)
PH (1) PH26669A (da)
PT (1) PT90017A (da)
ZA (1) ZA891997B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5385946A (en) * 1986-07-10 1995-01-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Method for treating hypertension with disubstituted granidine compounds
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5561128A (en) * 1989-05-19 1996-10-01 Hoechst-Roussel Pharmaceuticals, Inc. N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
ES2019228A6 (es) * 1990-02-13 1991-06-01 Espanola Prod Quimicos Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.
US5574070A (en) * 1990-05-25 1996-11-12 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Substituted guanidines having high binding to the sigma receptor and the use thereof
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
US5272148A (en) * 1992-09-09 1993-12-21 Hoechst-Roussel Pharmaceuticals Incorporated Heteroarenylpiperazines
CN1050604C (zh) * 1993-02-04 2000-03-22 明治制果株式会社 具有抗精神病作用的化合物
DE4333249A1 (de) * 1993-09-30 1995-04-06 Hoechst Schering Agrevo Gmbh Neue Mischungen aus Herbiziden und Antidots
EP0732332B1 (en) * 1995-03-17 2001-12-19 Aventis Pharmaceuticals Inc. Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1405319A (fr) * 1964-05-26 1965-07-09 Ile Auguil Soc Civ Procédé de préparation de l'(oxo-2 pyrrolidino-1)-1 (pyrrolidino-1)-4 butyne-2, et nouveaux sels de ce composé
JPS51125389A (en) * 1975-04-09 1976-11-01 Yoshitomi Pharmaceut Ind Ltd A process for preparing heterocyclic compovnds
DE2658762A1 (de) * 1976-12-24 1978-06-29 Hoechst Ag Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US4656173A (en) * 1985-04-24 1987-04-07 Bristol-Myers Company Antipsychotic benzisothiazole S-oxide compound
CA1278792C (en) * 1985-05-06 1991-01-08 Joseph P. Yevich Antipsychotic fused-ring pyridinylpiperazine derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides

Also Published As

Publication number Publication date
DK128889A (da) 1989-09-18
FI891222A0 (fi) 1989-03-15
FI891222A (fi) 1989-09-18
AU3137689A (en) 1989-09-21
IL89621A0 (en) 1989-09-10
EP0333137A1 (en) 1989-09-20
NO891151L (no) 1989-09-18
DK128889D0 (da) 1989-03-16
JPH024771A (ja) 1990-01-09
PH26669A (en) 1992-09-15
NZ228339A (en) 1991-07-26
US4780466A (en) 1988-10-25
NO891151D0 (no) 1989-03-16
KR890014522A (ko) 1989-10-24
HU203233B (en) 1991-06-28
HUT49874A (en) 1989-11-28
AU611780B2 (en) 1991-06-20
PT90017A (pt) 1989-11-10

Similar Documents

Publication Publication Date Title
AU2454788A (en) N-substituted derivatives of 1-desoxynojirimycin 1- desoxymannojirimycin, processes for their preparation and their use in medicaments
ZA881865B (en) Substituted 9-amino-tetrahydroacridines and related compounds,a process for their preparation and their use as medicaments
AU2114088A (en) New derivatives, a process for their preparation and their use
ZA891997B (en) Arylpiperazinylalkoxy derivatives of clyclic imides,a process for their preparation and their use as medicaments
PT82307A (en) 4-demethyl-4-epipodophyllotoxin derivatives a process for their preparation and their use as medicaments
ZA875043B (en) 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments
ZA901765B (en) Derivatives of thieno-triazolo-diazepine,a preparation process of the same and therapeutic compositions containing them
ZA843722B (en) Dibenzodiazepin derivatives,a process for their preparation and their use as medicaments
ZA879043B (en) Carbamoylimidazole derivatives,a process for their preparation,and their use as fungicides
ZA903305B (en) Thieno-triazolo-diazepine derivatives,a preparation process of the same and therapeutic compositions containing them
AU583965B2 (en) N-(pyrrol-1-yl) pyridinamines, a process for their preparation and their use as medicaments
AU1446588A (en) Novel pyrrolidine-2-(1,3-dicarbonyl) derivatives, a process for their preparation, agents containing them and their use
ZA901764B (en) Sulfonyl derivatives of thieno-triazolo-diazepines,a preparation process of the same and therapeutic compositions containing them
AU2836689A (en) Pyrazol- and indazolpyridin amines, a process for their preparation and their use as medicaments
AU609980B2 (en) Hydrazinocarbonyloxylabdanes, a process for their preparation and their use as medicaments
IL88568A0 (en) Aminopropanol derivatives of 1, 4:3, 6-dianhydro-hexitol nitrates,processes for their preparation and their use as medicaments
HU8902302D0 (en) Process for preparation of 1,2-hydroxy-phosphonates and derivatives thereof
ZA888194B (en) New acyllabdane derivatives,a process for their preparation,and their use as medicaments
NZ220805A (en) Cytorhodin s derivatives,a process for their preparation and their use as medicaments
AU2193588A (en) N-(substituted alkylidene)fused-bicycloalkylidene and heteroalkylidene quinolinamines, a process for their preparation and their use as medicaments
AU7762687A (en) Urdamycin G and derivatives thereof, a process for their preparation, and their use
ZA888936B (en) New labdane derivatives,a process for their preparation,and their use as medicaments
ZA888937B (en) New labdane derivatives,a process for their preparation,and their use as medicaments
ZA874559B (en) Cytorhodin s derivatives,a process for their preparation and their use as medicaments
ZA885154B (en) 9-halo-(z)-prostaglandin derivatives,process for their preparation and their use as a medicine