ZA891607B - Substrates for phospholipases - Google Patents

Substrates for phospholipases

Info

Publication number
ZA891607B
ZA891607B ZA891607A ZA891607A ZA891607B ZA 891607 B ZA891607 B ZA 891607B ZA 891607 A ZA891607 A ZA 891607A ZA 891607 A ZA891607 A ZA 891607A ZA 891607 B ZA891607 B ZA 891607B
Authority
ZA
South Africa
Prior art keywords
denotes
atoms
image
group
alkyl
Prior art date
Application number
ZA891607A
Other languages
English (en)
Inventor
Martina Dr Junius
Junius Dr Martina
Ulrich Dr Neumann
Neumann Dr Ulrich
Herbert Van Der Dr Eltz
Van Der Eltz Dr Herbert
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA891607B publication Critical patent/ZA891607B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C305/00Esters of sulfuric acids
    • C07C305/02Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C305/04Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated
    • C07C305/10Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA891607A 1988-03-04 1989-03-02 Substrates for phospholipases ZA891607B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3807123A DE3807123A1 (de) 1988-03-04 1988-03-04 Substrate fuer phospholipasen

Publications (1)

Publication Number Publication Date
ZA891607B true ZA891607B (en) 1989-11-29

Family

ID=6348884

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891607A ZA891607B (en) 1988-03-04 1989-03-02 Substrates for phospholipases

Country Status (10)

Country Link
US (1) US5091527A (enExample)
EP (1) EP0331167B1 (enExample)
JP (1) JPH023662A (enExample)
AT (1) ATE78484T1 (enExample)
AU (1) AU600869B2 (enExample)
CA (1) CA1337656C (enExample)
DE (2) DE3807123A1 (enExample)
ES (1) ES2034437T3 (enExample)
GR (1) GR3005766T3 (enExample)
ZA (1) ZA891607B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE145672T1 (de) * 1989-08-29 1996-12-15 Univ California Neue inhibitoren für hydrolytische enzyme und substrate und bestimmungsverfahren, selbige einschliessende verfahren und testsätze
US5352673A (en) * 1989-08-29 1994-10-04 Dennis Edward A Prodrugs
US5308766A (en) * 1989-08-29 1994-05-03 The Regents Of The University Of California Hydrolytic enzyme inhibitors/inactivators and methods for using same
DE4029845A1 (de) * 1990-09-20 1992-03-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von phospholipase in koerperfluessigkeiten
DE19622224A1 (de) 1996-02-16 1997-08-21 Max Planck Gesellschaft Phosphatidyloligoglycerine
JP4220603B2 (ja) * 1998-12-02 2009-02-04 アルフレッサファーマ株式会社 血小板活性化因子アセチルヒドロラーゼ活性の測定方法
EP1305323A1 (en) * 2000-07-25 2003-05-02 Eli Lilly And Company Chromogenic compound
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) * 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US6838452B2 (en) 2000-11-24 2005-01-04 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
CA2463816C (en) 2001-10-19 2014-07-08 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
US20150017671A1 (en) 2004-04-16 2015-01-15 Yaping Shou Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
EP2290094A1 (en) 2004-04-16 2011-03-02 Glaxo Group Limited Methods for detecting Lp-PLA2 activity and inhibition of Lp-PLA2 activity
US7807847B2 (en) 2004-07-09 2010-10-05 Vascular Biogenics Ltd. Process for the preparation of oxidized phospholipids
US9006217B2 (en) 2007-01-09 2015-04-14 Vascular Biogenics Ltd. High-purity phospholipids
US8569529B2 (en) 2007-01-09 2013-10-29 Vascular Biogenics Ltd. High-purity phospholipids
EP2826369A3 (en) * 2008-11-06 2015-03-18 Vascular Biogenics Ltd. Oxidized lipid compounds and uses thereof
US20140283157A1 (en) 2013-03-15 2014-09-18 Diadexus, Inc. Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
CA2968790A1 (en) 2014-11-26 2016-06-02 Vascular Biogenics Ltd. Oxidized lipids and treatment or prevention of fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493832A (en) * 1981-07-03 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
US4485045A (en) * 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
FR2517310A1 (fr) * 1981-11-27 1983-06-03 Unilever Nv Derives d'a-glycerophosphatidester, procede pour leur preparation, composition cosmetique ou pharmaceutique les contenant
JPS5931786A (ja) * 1982-08-16 1984-02-20 Hidetoshi Tsuchida ホスフアチジルコリン型リン脂質化合物
DE3516001A1 (de) * 1985-05-03 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Lipasefarbtest
EP0225129B1 (en) * 1985-11-29 1989-05-24 Takeda Chemical Industries, Ltd. Phospholipid derivatives, their production and use
AU607698B2 (en) * 1986-03-24 1991-03-14 Macquarie University Antigenic analogues of platelet activating factor (paf)
IL84387A0 (en) * 1987-11-06 1990-02-09 Rapaport Erich Pharmaceutical compositions containing a substituted phosphatide

Also Published As

Publication number Publication date
GR3005766T3 (enExample) 1993-06-07
EP0331167B1 (de) 1992-07-22
JPH0466864B2 (enExample) 1992-10-26
DE3807123A1 (de) 1989-09-14
AU3094389A (en) 1989-09-07
EP0331167A3 (en) 1989-11-15
US5091527A (en) 1992-02-25
AU600869B2 (en) 1990-08-23
JPH023662A (ja) 1990-01-09
ATE78484T1 (de) 1992-08-15
DE58901860D1 (en) 1992-08-27
ES2034437T3 (es) 1993-04-01
EP0331167A2 (de) 1989-09-06
CA1337656C (en) 1995-11-28

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