ZA891607B - Substrates for phospholipases - Google Patents

Substrates for phospholipases

Info

Publication number
ZA891607B
ZA891607B ZA891607A ZA891607A ZA891607B ZA 891607 B ZA891607 B ZA 891607B ZA 891607 A ZA891607 A ZA 891607A ZA 891607 A ZA891607 A ZA 891607A ZA 891607 B ZA891607 B ZA 891607B
Authority
ZA
South Africa
Prior art keywords
denotes
atoms
image
group
alkyl
Prior art date
Application number
ZA891607A
Other languages
English (en)
Inventor
Martina Dr Junius
Junius Dr Martina
Ulrich Dr Neumann
Neumann Dr Ulrich
Herbert Van Der Dr Eltz
Van Der Eltz Dr Herbert
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA891607B publication Critical patent/ZA891607B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C305/00—Esters of sulfuric acids
    • C07C305/02—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C305/04—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated
    • C07C305/10—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA891607A 1988-03-04 1989-03-02 Substrates for phospholipases ZA891607B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3807123A DE3807123A1 (de) 1988-03-04 1988-03-04 Substrate fuer phospholipasen

Publications (1)

Publication Number Publication Date
ZA891607B true ZA891607B (en) 1989-11-29

Family

ID=6348884

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891607A ZA891607B (en) 1988-03-04 1989-03-02 Substrates for phospholipases

Country Status (10)

Country Link
US (1) US5091527A (enExample)
EP (1) EP0331167B1 (enExample)
JP (1) JPH023662A (enExample)
AT (1) ATE78484T1 (enExample)
AU (1) AU600869B2 (enExample)
CA (1) CA1337656C (enExample)
DE (2) DE3807123A1 (enExample)
ES (1) ES2034437T3 (enExample)
GR (1) GR3005766T3 (enExample)
ZA (1) ZA891607B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69029269T2 (de) * 1989-08-29 1997-05-28 The Regents Of The University Of California, Berkeley, Calif. Neue inhibitoren für hydrolytische enzyme und substrate und bestimmungsverfahren, selbige einschliessende verfahren und testsätze
US5308766A (en) * 1989-08-29 1994-05-03 The Regents Of The University Of California Hydrolytic enzyme inhibitors/inactivators and methods for using same
US5352673A (en) * 1989-08-29 1994-10-04 Dennis Edward A Prodrugs
DE4029845A1 (de) * 1990-09-20 1992-03-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von phospholipase in koerperfluessigkeiten
DE19622224A1 (de) 1996-02-16 1997-08-21 Max Planck Gesellschaft Phosphatidyloligoglycerine
JP4220603B2 (ja) * 1998-12-02 2009-02-04 アルフレッサファーマ株式会社 血小板活性化因子アセチルヒドロラーゼ活性の測定方法
WO2002002570A1 (en) * 2000-07-25 2002-01-10 Eli Lilly And Company Chromogenic compound
US8071740B2 (en) * 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
AU2003222427B8 (en) * 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US6838452B2 (en) 2000-11-24 2005-01-04 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
EP1436313B1 (en) 2001-10-19 2010-09-22 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
US7741020B2 (en) * 2004-04-16 2010-06-22 Glaxo Group Limited Methods for detecting Lp-PLA2 activity and inhibition of Lp-PLA2 activity
US20150017671A1 (en) 2004-04-16 2015-01-15 Yaping Shou Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
US7807847B2 (en) 2004-07-09 2010-10-05 Vascular Biogenics Ltd. Process for the preparation of oxidized phospholipids
US8569529B2 (en) 2007-01-09 2013-10-29 Vascular Biogenics Ltd. High-purity phospholipids
US9006217B2 (en) 2007-01-09 2015-04-14 Vascular Biogenics Ltd. High-purity phospholipids
KR20110095288A (ko) 2008-11-06 2011-08-24 바스큘라 바이오제닉스 리미티드 산화된 지질 화합물 및 이의 용도
US20140283157A1 (en) 2013-03-15 2014-09-18 Diadexus, Inc. Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
CN106999506A (zh) 2014-11-26 2017-08-01 脉管生物生长有限公司 氧化脂质以及纤维化的治疗或预防
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493832A (en) * 1981-07-03 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
US4485045A (en) * 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
FR2517310A1 (fr) * 1981-11-27 1983-06-03 Unilever Nv Derives d'a-glycerophosphatidester, procede pour leur preparation, composition cosmetique ou pharmaceutique les contenant
JPS5931786A (ja) * 1982-08-16 1984-02-20 Hidetoshi Tsuchida ホスフアチジルコリン型リン脂質化合物
DE3516001A1 (de) * 1985-05-03 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Lipasefarbtest
EP0225129B1 (en) * 1985-11-29 1989-05-24 Takeda Chemical Industries, Ltd. Phospholipid derivatives, their production and use
AU607698B2 (en) * 1986-03-24 1991-03-14 Macquarie University Antigenic analogues of platelet activating factor (paf)
IL84387A0 (en) * 1987-11-06 1990-02-09 Rapaport Erich Pharmaceutical compositions containing a substituted phosphatide

Also Published As

Publication number Publication date
US5091527A (en) 1992-02-25
EP0331167A3 (en) 1989-11-15
AU600869B2 (en) 1990-08-23
ES2034437T3 (es) 1993-04-01
DE58901860D1 (en) 1992-08-27
GR3005766T3 (enExample) 1993-06-07
JPH023662A (ja) 1990-01-09
AU3094389A (en) 1989-09-07
ATE78484T1 (de) 1992-08-15
DE3807123A1 (de) 1989-09-14
JPH0466864B2 (enExample) 1992-10-26
EP0331167B1 (de) 1992-07-22
EP0331167A2 (de) 1989-09-06
CA1337656C (en) 1995-11-28

Similar Documents

Publication Publication Date Title
EP0331167A3 (en) Substrates for phospholipases
AU564688B2 (en) Phenoxazine derivatives (resorufin)
DE68927861D1 (de) 11 beta-substituierte progesteron-analoge
EP0377191A3 (de) Strahlungsempfindliches, ethylenisch ungesättigte, copolymerisierbare Verbindungen und Verfahren zu deren Herstellung
AU548974B2 (en) Oligoglucoside derivatives
DE3372091D1 (en) 2-(3-iodo-2-propynyloxy)-ethanol carbamates, preparation and use thereof as a microbicidal substance
ES2160171T3 (es) Forma purificada de estreptograminas, su preparacion y las composiciones farmaceuticas que la contienen.
PT95092A (pt) Processo para a preparacao enantiosselectiva de derivados da fenil-iso-serina e de preparacao da bacatina iii ou da 10-desacetilbacatina iii a partir daqueles derivados
ES2030241T3 (es) Compuestos estilenicamente insaturados, radiosensibles, copolimerizables y procedimiento para su obtencion.
DE3662879D1 (en) Polymerizable, hydroxylic groups bearing carbamoyloxyalkyldicarboxylic acid esters, process for their preparation and their use
DE3463775D1 (en) Negative photoresist formulations with radiation-absorbing additives
ES476314A1 (es) Procedimiento de obtencion de nuevas tiobutiramidas sustituidas.
SE8102047L (sv) Inhibitorer av kolesterolbiosyntes, deras framstellning och anvendning
DE59006169D1 (de) Verfahren zur Herstellung von siliciumorganischen Verbindungen.
RO85276A (ro) Procedeu pentru prepararea unor esteri tiazolidinici
SE8206499D0 (sv) Azino-rifamyciner och forfarande for framstellning derav
ES2076623T3 (es) 3,4-dihidro-naftalinas sustituidas, su procedimiento de preparacion y medicamentos que las contienen.
ATE61341T1 (de) N-substituierte, estergruppen enthaltende acrylamide.