ZA891107B - 1,4-benzoxazine and 1,4-benzothiazine derivatives and process for their preparation - Google Patents

1,4-benzoxazine and 1,4-benzothiazine derivatives and process for their preparation

Info

Publication number
ZA891107B
ZA891107B ZA891107A ZA891107A ZA891107B ZA 891107 B ZA891107 B ZA 891107B ZA 891107 A ZA891107 A ZA 891107A ZA 891107 A ZA891107 A ZA 891107A ZA 891107 B ZA891107 B ZA 891107B
Authority
ZA
South Africa
Prior art keywords
benzoxazine
preparation
benzothiazine derivatives
benzothiazine
derivatives
Prior art date
Application number
ZA891107A
Other languages
English (en)
Inventor
Mario Varasi
Varasi Mario
Piero Melloni
Melloni Piero
Maria Antonietta Cervini
Antonietta Cervini Maria
Alberto Bonsignori
Bonsignori Alberto
Roberto Commisso
Commisso Roberto
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA891107B publication Critical patent/ZA891107B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
ZA891107A 1988-02-15 1989-02-13 1,4-benzoxazine and 1,4-benzothiazine derivatives and process for their preparation ZA891107B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888803419A GB8803419D0 (en) 1988-02-15 1988-02-15 1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation

Publications (1)

Publication Number Publication Date
ZA891107B true ZA891107B (en) 1989-10-25

Family

ID=10631705

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891107A ZA891107B (en) 1988-02-15 1989-02-13 1,4-benzoxazine and 1,4-benzothiazine derivatives and process for their preparation

Country Status (19)

Country Link
US (1) US5084454A (xx)
EP (1) EP0359790B1 (xx)
JP (1) JPH02503200A (xx)
KR (1) KR900700468A (xx)
CA (1) CA1327575C (xx)
DE (1) DE68910451T2 (xx)
DK (1) DK506289A (xx)
ES (1) ES2012648A6 (xx)
FI (1) FI894798A0 (xx)
GB (1) GB8803419D0 (xx)
GR (1) GR1000373B (xx)
HU (1) HU204517B (xx)
IE (1) IE890464L (xx)
IL (1) IL89035A (xx)
NZ (1) NZ227739A (xx)
PT (1) PT89715B (xx)
RU (1) RU1826968C (xx)
WO (1) WO1989007596A1 (xx)
ZA (1) ZA891107B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240927A (en) * 1992-05-19 1993-08-31 Hoechst-Roussel Pharmaceuticals Incorporated Benzo[β]thiophen-3-yl piperazines as antipsychotic agents
FR2702477B1 (fr) * 1993-03-08 1995-04-28 Synthelabo Dérivés de benzoxazine, leur préparation et leur application en thérapeutique.
US5691323A (en) * 1995-05-12 1997-11-25 Merck & Co., Inc. Muscarine antagonists
US6162803A (en) * 1998-04-08 2000-12-19 American Home Products Corp. Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression
JP3201998B2 (ja) * 1998-12-16 2001-08-27 サムソン ジェネラル ケミカルズ カンパニー リミテッド （ｓ）−ベンゾオキサジン誘導体の製造方法及び（ｒ）−ベンゾオキサジン誘導体のラセミ化方法
US6221863B1 (en) 1999-01-07 2001-04-24 American Home Products Corp. 3,4-dihydro-2H-benzo[1,4]oxazine derivatives
TW546299B (en) * 1999-01-07 2003-08-11 Wyeth Corp 3,4-dihydro-2H-benzo[1,4]oxazinyl-methyl-[3-(1H-indol-3-yl)-alkyl]-amines
US6313114B1 (en) 1999-01-07 2001-11-06 American Home Products Corp 3,4-Dihydro-2H-benzo[1,4]oxazinyl-methyl)-[3-(1H-indol-3yl)-alkyl]- amines
AU2494300A (en) * 1999-01-07 2000-07-24 American Home Products Corporation 3,4-dihydro-2h-benzo(1,4)oxazine derivatives
US6583183B2 (en) 1999-09-23 2003-06-24 Pharmacia Corporation Substituted n-phenyl-n-fused-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
US6544974B2 (en) 1999-09-23 2003-04-08 G.D. Searle & Co. (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesteryl ester transfer protein activity
ES2291984T3 (es) * 2003-12-09 2008-03-01 F. Hoffmann-La Roche Ag Derivados de benzoxazina y su empleo.
CN101836993B (zh) 2010-05-20 2011-06-22 山东大学 2，3-二氢-3-羟甲基-6-氨基-[1，4]-苯并噁嗪在制备诱导胚胎干细胞向血管内皮细胞分化药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058980A (en) * 1962-10-16 Substitution products of benzo-
GB2080791B (en) * 1980-06-19 1984-02-22 Erba Farmitalia 1,4-benzoxazines
GB8511526D0 (en) * 1985-05-07 1985-06-12 Hoechst Uk Ltd 1 4 benzodioxin & 1 4 benzoxazine derivatives
EP0233728A1 (en) * 1986-02-11 1987-08-26 Takeda Chemical Industries, Ltd. 1,4-Benzoxazine derivatives their production and use

Also Published As

Publication number Publication date
NZ227739A (en) 1990-08-28
US5084454A (en) 1992-01-28
DK506289D0 (da) 1989-10-12
IE890464L (en) 1989-08-15
ES2012648A6 (es) 1990-04-01
IL89035A0 (en) 1989-08-15
GR1000373B (el) 1992-06-30
DE68910451D1 (de) 1993-12-09
FI894798A0 (fi) 1989-10-10
PT89715B (pt) 1994-03-31
JPH02503200A (ja) 1990-10-04
GB8803419D0 (en) 1988-03-16
EP0359790A1 (en) 1990-03-28
EP0359790B1 (en) 1993-11-03
HUT56354A (en) 1991-08-28
HU891441D0 (en) 1990-01-28
RU1826968C (ru) 1993-07-07
WO1989007596A1 (en) 1989-08-24
KR900700468A (ko) 1990-08-13
DE68910451T2 (de) 1994-03-03
IL89035A (en) 1994-05-30
PT89715A (pt) 1989-10-04
HU204517B (en) 1992-01-28
DK506289A (da) 1989-10-12
CA1327575C (en) 1994-03-08

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