ZA889166B - 1,7-annelated indolecarboxylic acid esters and -amides - Google Patents

1,7-annelated indolecarboxylic acid esters and -amides

Info

Publication number
ZA889166B
ZA889166B ZA889166A ZA889166A ZA889166B ZA 889166 B ZA889166 B ZA 889166B ZA 889166 A ZA889166 A ZA 889166A ZA 889166 A ZA889166 A ZA 889166A ZA 889166 B ZA889166 B ZA 889166B
Authority
ZA
South Africa
Prior art keywords
annelated
amides
acid esters
indolecarboxylic acid
indolecarboxylic
Prior art date
Application number
ZA889166A
Other languages
English (en)
Inventor
Derk Hamminga
Hamminga Derk
Hans Heinz Haeck
Heinz Haeck Hans
Ineke Van Wijngaarden
Van Wijngaarden Ineke
Wouter Wouters
Wouters Wouter
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of ZA889166B publication Critical patent/ZA889166B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
ZA889166A 1987-12-10 1988-12-07 1,7-annelated indolecarboxylic acid esters and -amides ZA889166B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8702981 1987-12-10

Publications (1)

Publication Number Publication Date
ZA889166B true ZA889166B (en) 1990-05-30

Family

ID=19851068

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA889166A ZA889166B (en) 1987-12-10 1988-12-07 1,7-annelated indolecarboxylic acid esters and -amides

Country Status (8)

Country Link
US (1) US4985420A (da)
EP (1) EP0322016A1 (da)
JP (1) JPH01190680A (da)
AU (1) AU621071B2 (da)
DK (1) DK680788A (da)
IL (1) IL88615A (da)
NZ (1) NZ227229A (da)
ZA (1) ZA889166B (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
US5198437A (en) * 1987-12-10 1993-03-30 Duphar International Research B.V. 1,7-annelated indolecarboxylic acid esters and amides
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0377238A1 (en) * 1988-12-22 1990-07-11 Duphar International Research B.V New annelated indolo (3,2-c)-lactams
PH26955A (en) * 1989-03-08 1992-12-03 Kali Chemie Pharma Gmbh Novel 1,7-fused 1H-indole-2-carboxylic acid N-(1,4-benzodiazepin-3-YL) amides
DE3907388A1 (de) * 1989-03-08 1990-09-13 Kali Chemie Pharma Gmbh Verfahren zur herstellung von indolcarbonsaeurederivaten
GB8913646D0 (en) * 1989-06-14 1989-08-02 Glaxo Group Ltd Chemical compounds
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
EP0436245A1 (en) * 1989-12-27 1991-07-10 Duphar International Research B.V Substituted 3,4-annelated benzimidazol-2(1H)-ones
DE4128015A1 (de) * 1991-08-23 1993-02-25 Kali Chemie Pharma Gmbh 1,7-anellierte 2-(piperazinoalkyl)indol-derivate sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindugnen enthaltende arzneimittel
JPH05310732A (ja) * 1992-03-12 1993-11-22 Mitsubishi Kasei Corp シンノリン−３−カルボン酸誘導体
DE4304806A1 (de) * 1993-02-17 1994-08-18 Kali Chemie Pharma Gmbh 5-Phenyl-pyrrolo-1,4-benzoxazin- und -thiazin-Derivate sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
NZ314105A (en) * 1996-02-02 1997-12-19 Sumitomo Pharma Guanidine derivative substituted with a substituted indole which is peri condensed with a heterocyclic ring
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
WO2003024976A2 (en) * 2001-09-21 2003-03-27 Pharmacia & Upjohn Company Tricyclic indole derivatives as 5-ht ligands
MXPA04004373A (es) 2001-11-09 2004-08-11 Upjohn Co Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades.
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
HUE037938T2 (hu) 2008-11-19 2018-09-28 Forum Pharmaceuticals Inc Skizofrénia negatív tüneteinek kezelése (R)-7-klór-N-(kinuklidin-3-il)benzo[b]tiofén-2-karboxamiddal és ennek gyógyszerészetileg elfogadható sójával
RU2011150248A (ru) * 2009-05-11 2013-06-20 Энвиво Фармасьютикалз, Инк. Лечение когнитивных расстройств с определенными рецепторами альфа-7 никотиновой кислоты в комбинации с ингибиторами ацетилхолинэстеразы
WO2011082266A2 (en) 2009-12-30 2011-07-07 Arqule, Inc. Substituted heterocyclic compounds
PT3029039T (pt) 2010-05-17 2017-11-28 Forum Pharmaceuticals Inc Formulações farmacêuticas que compreendem formas cristalinas de cloridrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo(b)tiofeno-2-carboxamida mono-hidratado
CA2872005A1 (en) 2012-05-08 2013-11-14 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
CN103923105B (zh) * 2014-04-17 2016-08-24 北京大学 2-中氮茚甲酰胺类化合物及其制备和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
ATE86110T1 (de) * 1984-12-20 1993-03-15 Sandoz Ag Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten.
GB8525844D0 (en) * 1985-10-19 1985-11-20 Beecham Group Plc Compounds
ZA868369B (en) * 1986-01-10 1987-11-25 Israel State Derivatives of quinuclidine

Also Published As

Publication number Publication date
JPH01190680A (ja) 1989-07-31
DK680788D0 (da) 1988-12-07
AU621071B2 (en) 1992-03-05
EP0322016A1 (en) 1989-06-28
NZ227229A (en) 1991-03-26
AU2669688A (en) 1989-06-15
IL88615A (en) 1992-11-15
IL88615A0 (en) 1989-07-31
US4985420A (en) 1991-01-15
DK680788A (da) 1989-06-11

Similar Documents

Publication Publication Date Title
ZA889166B (en) 1,7-annelated indolecarboxylic acid esters and -amides
JPS6470462A (en) Tetrahydrocarbazole-1-alkanoic acids
GB2207672B (en) Sulphonamidothienylcarboxyic acid compounds
ZA882318B (en) 5-substituted quinolone-and naphthyridonecarboxylic acid derivatives
US4801609B1 (en) Mercapto-acylamino acid antihypertensives
EP0291245A3 (en) Benzoylaminophenoxybutanoic acid derivatives
GB2203149B (en) New ribofuranuronic acid derivatives
EP0313517A3 (en) Aliphatic esters of 1,3,2-oxazaphospholidines
GB8703749D0 (en) Piperazinecarboxylic acid
GB8630759D0 (en) Carboxylic acid derivatives
ZW9288A1 (en) Hydocinnamic acid derivatives
GB2207428B (en) Naphthalenepropionic acid derivatives
GB8723895D0 (en) Preparing-phenyl-propionic acid derivative
EP0276947A3 (en) Carboxylic acid derivatives
IL85037A0 (en) 2,1-benzothiazepine-2,2-dioxide-5-carboxylic acid derivatives
JPS6413096A (en) 1-aminoethylphosphinic acid derivative
JPS6413095A (en) 1-aminoethylphosphinic acid
EP0421751A3 (en) Substituted acrylamido-penicillanic acid esters
IE872256L (en) Thiopenem-carboxylic acid derivative
KR950013765B1 (en) Hydroxyindole esters
GB8710781D0 (en) 3-hydroxy-3-methylpentanedioic acid
GB8703750D0 (en) Piperazinecarboxylic acid
IE871285L (en) 2-cyanonicotinic acid derivatives
IE873378L (en) Furanuronic acid derivatives
IE871307L (en) 2-oxocyclohexaneacetic acid esters