IL88615A - 1,7-annelated indolecarboxylic acid esters and carboxamides,their preparation and pharmaceutical compositions containing them - Google Patents

1,7-annelated indolecarboxylic acid esters and carboxamides,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL88615A
IL88615A IL88615A IL8861588A IL88615A IL 88615 A IL88615 A IL 88615A IL 88615 A IL88615 A IL 88615A IL 8861588 A IL8861588 A IL 8861588A IL 88615 A IL88615 A IL 88615A
Authority
IL
Israel
Prior art keywords
annelated
carboxamides
preparation
pharmaceutical compositions
acid esters
Prior art date
Application number
IL88615A
Other languages
English (en)
Other versions
IL88615A0 (en
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of IL88615A0 publication Critical patent/IL88615A0/xx
Publication of IL88615A publication Critical patent/IL88615A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
IL88615A 1987-12-10 1988-12-07 1,7-annelated indolecarboxylic acid esters and carboxamides,their preparation and pharmaceutical compositions containing them IL88615A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8702981 1987-12-10

Publications (2)

Publication Number Publication Date
IL88615A0 IL88615A0 (en) 1989-07-31
IL88615A true IL88615A (en) 1992-11-15

Family

ID=19851068

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88615A IL88615A (en) 1987-12-10 1988-12-07 1,7-annelated indolecarboxylic acid esters and carboxamides,their preparation and pharmaceutical compositions containing them

Country Status (8)

Country Link
US (1) US4985420A (xx)
EP (1) EP0322016A1 (xx)
JP (1) JPH01190680A (xx)
AU (1) AU621071B2 (xx)
DK (1) DK680788A (xx)
IL (1) IL88615A (xx)
NZ (1) NZ227229A (xx)
ZA (1) ZA889166B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
US5198437A (en) * 1987-12-10 1993-03-30 Duphar International Research B.V. 1,7-annelated indolecarboxylic acid esters and amides
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0377238A1 (en) * 1988-12-22 1990-07-11 Duphar International Research B.V New annelated indolo (3,2-c)-lactams
PH26955A (en) * 1989-03-08 1992-12-03 Kali Chemie Pharma Gmbh Novel 1,7-fused 1H-indole-2-carboxylic acid N-(1,4-benzodiazepin-3-YL) amides
DE3907388A1 (de) * 1989-03-08 1990-09-13 Kali Chemie Pharma Gmbh Verfahren zur herstellung von indolcarbonsaeurederivaten
GB8913646D0 (en) * 1989-06-14 1989-08-02 Glaxo Group Ltd Chemical compounds
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
EP0436245A1 (en) * 1989-12-27 1991-07-10 Duphar International Research B.V Substituted 3,4-annelated benzimidazol-2(1H)-ones
DE4128015A1 (de) * 1991-08-23 1993-02-25 Kali Chemie Pharma Gmbh 1,7-anellierte 2-(piperazinoalkyl)indol-derivate sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindugnen enthaltende arzneimittel
JPH05310732A (ja) * 1992-03-12 1993-11-22 Mitsubishi Kasei Corp シンノリン−３−カルボン酸誘導体
DE4304806A1 (de) * 1993-02-17 1994-08-18 Kali Chemie Pharma Gmbh 5-Phenyl-pyrrolo-1,4-benzoxazin- und -thiazin-Derivate sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
NZ314105A (en) * 1996-02-02 1997-12-19 Sumitomo Pharma Guanidine derivative substituted with a substituted indole which is peri condensed with a heterocyclic ring
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
WO2003024976A2 (en) * 2001-09-21 2003-03-27 Pharmacia & Upjohn Company Tricyclic indole derivatives as 5-ht ligands
MXPA04004373A (es) 2001-11-09 2004-08-11 Upjohn Co Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades.
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
HUE037938T2 (hu) 2008-11-19 2018-09-28 Forum Pharmaceuticals Inc Skizofrénia negatív tüneteinek kezelése (R)-7-klór-N-(kinuklidin-3-il)benzo[b]tiofén-2-karboxamiddal és ennek gyógyszerészetileg elfogadható sójával
RU2011150248A (ru) * 2009-05-11 2013-06-20 Энвиво Фармасьютикалз, Инк. Лечение когнитивных расстройств с определенными рецепторами альфа-7 никотиновой кислоты в комбинации с ингибиторами ацетилхолинэстеразы
WO2011082266A2 (en) 2009-12-30 2011-07-07 Arqule, Inc. Substituted heterocyclic compounds
PT3029039T (pt) 2010-05-17 2017-11-28 Forum Pharmaceuticals Inc Formulações farmacêuticas que compreendem formas cristalinas de cloridrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo(b)tiofeno-2-carboxamida mono-hidratado
CA2872005A1 (en) 2012-05-08 2013-11-14 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
CN103923105B (zh) * 2014-04-17 2016-08-24 北京大学 2-中氮茚甲酰胺类化合物及其制备和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
ATE86110T1 (de) * 1984-12-20 1993-03-15 Sandoz Ag Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten.
GB8525844D0 (en) * 1985-10-19 1985-11-20 Beecham Group Plc Compounds
ZA868369B (en) * 1986-01-10 1987-11-25 Israel State Derivatives of quinuclidine

Also Published As

Publication number Publication date
JPH01190680A (ja) 1989-07-31
DK680788D0 (da) 1988-12-07
AU621071B2 (en) 1992-03-05
EP0322016A1 (en) 1989-06-28
NZ227229A (en) 1991-03-26
ZA889166B (en) 1990-05-30
AU2669688A (en) 1989-06-15
IL88615A0 (en) 1989-07-31
US4985420A (en) 1991-01-15
DK680788A (da) 1989-06-11

Similar Documents

Publication Publication Date Title
IL88615A (en) 1,7-annelated indolecarboxylic acid esters and carboxamides,their preparation and pharmaceutical compositions containing them
IL87079A0 (en) Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them
IL86798A (en) 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them
IL88433A0 (en) Diarylstyrylquinoline diacids and pharmaceutical compositions containing them
IL85969A0 (en) Ribofuranuronic acid derivatives and pharmaceutical compositions containing them
IL87800A0 (en) Dioxolane-2-carboxylic acids and pharmaceutical compositions comprising them
IL79025A0 (en) Quinolonecarboxylic acid esters,their preparation and pharmaceutical compositions containing them
IL87644A0 (en) Oxadiazolyl-azabicycloheptanes,their preparation and pharmaceutical compositions containing them
IL86244A0 (en) Substituted benzamides,their preparation and pharmaceutical compositions containing them
IL81179A (en) N-phenylbutenyl substituted azaheterocyclic carboxylic acids,their preparation and pharmaceutical compositions comprising them
IL85290A0 (en) Substituted 3,4-dihydro-2h-benzopyrans,processes for their preparation and pharmaceutical compositions containing same
IL88002A0 (en) 2,2-dimethylchromene derivatives,their preparation and pharmaceutical compositions containing them
IL77849A0 (en) Aryldihydropyridinedicarboxylic acid ester derivatives,their preparation and pharmaceutical compositions containing them
IL79181A0 (en) 3-(substituted)propenylaminothiazolylcephalosporanic acids and esters thereof,their preparation and pharmaceutical compositions containing them
IL84724A0 (en) Substituted aminomethyl-5,6,7,8-tetrahydronaphthyloxyacetic acids and esters and amides thereof,their preparation and pharmaceutical compositions containing them
NZ224923A (en) 2-methoxymethyl-penem-3-carboxylic acid derivatives and pharmaceutical compositions
CY1739A (en) Piperazinecarboxylic acid its preparation and pharmaceutical compositions containing it
IL87876A0 (en) Catechol carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL90231A0 (en) 1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them
IL75603A0 (en) 1,3-dioxanylheptenoic acid derivatives,their preparation and pharmaceutical compositions containing them
IL86926A0 (en) 1h-pyrazole-1-alkanamides,their preparation and pharmaceutical compositions containing them
NZ218614A (en) 16,17-butylidenedioxy-6,9-difluoro-11-hydroxy-3, 20-dioxopregna-1,4-diene-21-oic acid esters and pharmaceutical compositions
IL88658A0 (en) 8,9-annelated beta-carbolines and 3,4-dihydro-beta-carbolines,their preparation and pharmaceutical compositions containing them
NZ221018A (en) 2-penem-3-carboxylic acid derivatives and pharmaceutical compositions
IL77799A0 (en) Dihydropyridinedicarboxylic acid ester derivatives,their preparation and pharmaceutical compositions containing them