ZA887047B - Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof - Google Patents

Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof

Info

Publication number
ZA887047B
ZA887047B ZA887047A ZA887047A ZA887047B ZA 887047 B ZA887047 B ZA 887047B ZA 887047 A ZA887047 A ZA 887047A ZA 887047 A ZA887047 A ZA 887047A ZA 887047 B ZA887047 B ZA 887047B
Authority
ZA
South Africa
Prior art keywords
diphenylmethylenebicycloheptenes
diphenylmethylenebicycloheptene
diphenylmethylenebicycloheptanes
diphenylmethylenebicycloheptane
medicaments
Prior art date
Application number
ZA887047A
Other languages
English (en)
Inventor
Herbert Siegel
Siegel Herbert
Ernold Granzer
Granzer Ernold
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA887047B publication Critical patent/ZA887047B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
ZA887047A 1987-09-23 1988-09-21 Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof ZA887047B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731913 DE3731913A1 (de) 1987-09-23 1987-09-23 Pharmazeutische praeparate enthaltend ein 7-diphenylmethylenbicycloheptan- oder 7-diphenylmethylenbicyclohepten-derivat, die verwendung dieser verbindungen als arzneimittel sowie neue 7-diphenylmethylenbicycloheptane und 7-diphenylmethylenbicloheptene und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA887047B true ZA887047B (en) 1989-06-28

Family

ID=6336607

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA887047A ZA887047B (en) 1987-09-23 1988-09-21 Pharmaceutical products containing a 7-diphenylmethylenebicycloheptane or 7-diphenylmethylenebicycloheptene derivative,the use of these compounds as medicaments,and new 7-diphenylmethylenebicycloheptanes and 7-diphenylmethylenebicycloheptenes and processes for the preparation thereof

Country Status (13)

Country Link
US (1) US5141937A (xx)
EP (1) EP0308839A3 (xx)
JP (1) JPH01113351A (xx)
KR (1) KR890005041A (xx)
AU (1) AU612177B2 (xx)
DE (1) DE3731913A1 (xx)
DK (1) DK527388A (xx)
FI (1) FI884343A (xx)
HU (2) HU204431B (xx)
IL (1) IL87818A0 (xx)
NO (1) NO884207L (xx)
PT (1) PT88572B (xx)
ZA (1) ZA887047B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9303670A (es) * 1992-06-19 1994-05-31 Black James Foundation Derivados de biciclooctano y bicicloheptano, meto do para su preparacion y composiciones farmaceuticas que los contienen.
KR20060066070A (ko) 2003-07-28 2006-06-15 스미스클라인 비참 코포레이션 에스트로겐 수용체의 조절제로서의 시클로알킬리덴 화합물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550186A (en) * 1983-07-11 1985-10-29 Duke University Binuclear copper (II) carboxylates formed from amine-carboxyboranes
DE3410498A1 (de) * 1984-03-22 1985-10-03 Hoechst Ag, 6230 Frankfurt N-bicycloheptyl- und n-bicycloheptenyl-imidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate

Also Published As

Publication number Publication date
DK527388A (da) 1989-03-24
EP0308839A2 (de) 1989-03-29
EP0308839A3 (de) 1989-09-20
PT88572B (pt) 1992-11-30
HU204431B (en) 1992-01-28
AU612177B2 (en) 1991-07-04
PT88572A (pt) 1988-10-01
AU2273088A (en) 1989-03-23
KR890005041A (ko) 1989-05-11
DE3731913A1 (de) 1989-04-06
HU200991B (en) 1990-09-28
HUT48199A (en) 1989-05-29
NO884207L (no) 1989-03-28
DK527388D0 (da) 1988-09-22
JPH01113351A (ja) 1989-05-02
FI884343A (fi) 1989-03-24
NO884207D0 (no) 1988-09-22
US5141937A (en) 1992-08-25
HU902054D0 (en) 1990-07-28
IL87818A0 (en) 1989-03-31
FI884343A0 (fi) 1988-09-21

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