ZA886840B - New amino acid esters,a process for their preparation medicaments containing them,and the use thereof - Google Patents

New amino acid esters,a process for their preparation medicaments containing them,and the use thereof

Info

Publication number
ZA886840B
ZA886840B ZA886840A ZA886840A ZA886840B ZA 886840 B ZA886840 B ZA 886840B ZA 886840 A ZA886840 A ZA 886840A ZA 886840 A ZA886840 A ZA 886840A ZA 886840 B ZA886840 B ZA 886840B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid esters
medicaments containing
new amino
preparation medicaments
Prior art date
Application number
ZA886840A
Other languages
English (en)
Inventor
Wolfgang Rueger
Rueger Wolfgang
Hansjoerg Urbach
Urbach Hansjoerg
Reinhard Becker
Becker Reinhard
Franz Hock
Hock Franz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA886840B publication Critical patent/ZA886840B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA886840A 1987-09-16 1988-09-14 New amino acid esters,a process for their preparation medicaments containing them,and the use thereof ZA886840B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731085 DE3731085A1 (de) 1987-09-16 1987-09-16 Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung

Publications (1)

Publication Number Publication Date
ZA886840B true ZA886840B (en) 1989-04-26

Family

ID=6336129

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886840A ZA886840B (en) 1987-09-16 1988-09-14 New amino acid esters,a process for their preparation medicaments containing them,and the use thereof

Country Status (13)

Country Link
US (1) US5114962A (pt)
EP (1) EP0307872A3 (pt)
JP (1) JPH01128997A (pt)
KR (1) KR890005145A (pt)
AU (1) AU617118B2 (pt)
DE (1) DE3731085A1 (pt)
DK (1) DK513188A (pt)
FI (1) FI884225A (pt)
IL (1) IL87739A (pt)
NO (1) NO884110L (pt)
NZ (1) NZ226184A (pt)
PT (1) PT88516B (pt)
ZA (1) ZA886840B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
US5137906A (en) * 1990-03-20 1992-08-11 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with benzimidazole angiotensin-II receptor antagonists
US5140037A (en) 1990-03-20 1992-08-18 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with imidazole angiotensin-ii receptor antagonists
US5173494A (en) * 1990-03-20 1992-12-22 E. I. Du Pont De Nemours And Company Specific inhibition of angiotensin-II binding to angiotensin-II receptor subtype-2
US5155126A (en) * 1990-03-20 1992-10-13 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with pyrazole, pyrrole and triazole angiotensin-II receptor antagonists
US5179113A (en) * 1990-03-20 1993-01-12 E. I. Du Pont De Nemours And Company Treatment of central nervous disorders with imidazole compounds
US5091390A (en) * 1990-09-20 1992-02-25 E. I. Du Pont De Nemours And Company Treatment of CNS disorders with 4,5,6,7-tetrahydro-1H-imidazo (4,5-)-pyridines and analogs

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
US4654331A (en) * 1981-07-13 1987-03-31 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
GR76525B (pt) * 1981-07-13 1984-08-10 Merck & Co Inc
US4479947A (en) * 1981-07-13 1984-10-30 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
JPS5970683A (ja) * 1982-10-12 1984-04-21 Kyoto Yakuhin Kogyo Kk １，３−ジオキソレン−２−オン誘導体
US4453005A (en) * 1982-12-06 1984-06-05 Merck Frosst Canada, Inc. Process for preparing substituted phenylalkenoic acids
JPS59231082A (ja) * 1983-06-14 1984-12-25 Kanebo Ltd ４−クロロ−４−メチル−５−メチレン−１，３−ジオキソラン−２−オン
US4822803A (en) * 1983-10-31 1989-04-18 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid hydrazides useful as inhibitors of leukotriene biosynthesis
JPS60246385A (ja) * 1984-05-22 1985-12-06 Sankyo Co Ltd ピリド〔３，４−ｂ〕インド−ル誘導体
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
DE3432307A1 (de) * 1984-09-03 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
EP0230922A2 (de) * 1986-01-21 1987-08-05 Boehringer Ingelheim Kg Verwendung von Peptiden zur Herstellung von Mitteln zur Behandlung von Coronarerkrankungen oder organischem Hirnsyndrom
US4777267A (en) * 1986-02-07 1988-10-11 Kanebo Ltd. 1,3-dioxol-2-one derivatives
DE3610391A1 (de) * 1986-03-27 1987-10-08 Hoechst Ag Verbindungen mit nootroper wirkung, diese enthaltende mittel und deren verwendung bei der behandlung und prophylaxe cognitiver dysfunktionen
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3641451A1 (de) * 1986-12-04 1988-06-16 Hoechst Ag Derivate bicyclischer aminocarbonsaeuren, verfahren und zwischenprodukte zu deren herstellung sowie deren verwendung

Also Published As

Publication number Publication date
KR890005145A (ko) 1989-05-13
DK513188A (da) 1989-03-17
DK513188D0 (da) 1988-09-15
NO884110D0 (no) 1988-09-15
PT88516B (pt) 1992-11-30
AU617118B2 (en) 1991-11-21
PT88516A (pt) 1988-10-01
FI884225A0 (fi) 1988-09-14
US5114962A (en) 1992-05-19
NZ226184A (en) 1991-03-26
EP0307872A3 (de) 1990-07-04
FI884225A (fi) 1989-03-17
EP0307872A2 (de) 1989-03-22
IL87739A (en) 1993-03-15
IL87739A0 (en) 1989-02-28
DE3731085A1 (de) 1989-04-06
NO884110L (no) 1989-03-17
AU2227988A (en) 1989-03-16
JPH01128997A (ja) 1989-05-22

Similar Documents

Publication Publication Date Title
EP0300189A3 (en) New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
ZA881865B (en) Substituted 9-amino-tetrahydroacridines and related compounds,a process for their preparation and their use as medicaments
AU7171787A (en) 1-hydroxy-2-pyridones, a process for their preparation, and medicaments which contain them, and intermediates formed in the preparation of the 1-hydroxy-2-pyridones
ZA875043B (en) 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments
IL86027A0 (en) New 2-acylpyrrolidine derivatives,a process for the preparation thereof,agents containing them,and their use
ZA889306B (en) New derivatives of cyclic amino acids,a process for the preparation thereof,agents containing them,and the use thereof
ZA89432B (en) Novel amino acid glycerides,processes for their preparation,medicaments containing them and their use
ZA884878B (en) Substituted benzimidazoles,a process for the preparation thereof,pharmaceutical formulations containing them,and the use thereof
ZA864604B (en) 1,8-bridged 4-quinolone-3-carboxylic acids,a process for their preparation,medicaments containing these compounds and their use for the preparation of medicaments
ZA886840B (en) New amino acid esters,a process for their preparation medicaments containing them,and the use thereof
PT86470A (en) Novel carbamoyloxylabdanes intermediates and a process for the preparation thereof and their use as medicaments
ZA887264B (en) Renin-inhibiting dipeptides,a process for the preparation thereof,agents containing them,and their use
IL90031A0 (en) Amino acid esters,a process for the preparation thereof,pharmaceuticals containing them,and the use thereof
GR3001052T3 (en) Novel 16,17-acetalsubstituted pregnane-21-oic acid derivatives, process for the preparation thereof and pharmaceutical preparation containing them
DE3564680D1 (en) Gamma-aminobutyric acid derivatives, process for production thereof, and use thereof as medicaments
ZA8814B (en) A process for the preparation of lipophilic amino acid derivatives,and lipophilic amino acid derivatives
ZA893374B (en) Hydrazinocarbonyloxylabdanes,a process for their preparation and their use as medicaments
PT81880A (en) (1,2,4-oxadiazol-3-yl)-arymethanones a process for their preparation and their use as medicaments
ZA88409B (en) 3-methylenespiro/benzofuranpiperidines/,intermediates and a process for the preparation thereof,and their use as medicaments
ZA866444B (en) Spergualin-related compounds,a process for their preparation and their use as medicaments
ZA888194B (en) New acyllabdane derivatives,a process for their preparation,and their use as medicaments
EP0422439A3 (en) Aminomethanephosphonic acid esters, process for their preparation and their use
IL87678A (en) N-methylene-2,3 -cycloalkylene- (and 2,3-heteroalkylene) -4-quinolinamines, a process for their preparation and pharmaceutical compositions containing them
ZA886675B (en) The use of certain 6-mercaptopurines for the preparation of a pharmaceutical,and a process for the preparation of the pharmaceutical
IL94221A0 (en) Tetrahydroisoquino(2,1,c)(1,3)-benzodiazepines,a process for their preparation and their use as medicaments