ZA883905B - Purification of tpa - Google Patents

Purification of tpa

Info

Publication number
ZA883905B
ZA883905B ZA883905A ZA883905A ZA883905B ZA 883905 B ZA883905 B ZA 883905B ZA 883905 A ZA883905 A ZA 883905A ZA 883905 A ZA883905 A ZA 883905A ZA 883905 B ZA883905 B ZA 883905B
Authority
ZA
South Africa
Prior art keywords
tpa
purification
Prior art date
Application number
ZA883905A
Other languages
English (en)
Inventor
Peter Arletti Dephillips
Arletti Dephillips Peter
Patrick Joseph Mcdevitt
Joseph Mcdevitt Patrick
Samuel Gregg Franklin
Gregg Franklin Samuel
Robert David Sitrin
David Sitrin Robert
Kyung Oh Johanson
Oh Johanson Kyung
James Edward Strickler
Edward Strickler James
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA883905B publication Critical patent/ZA883905B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA883905A 1987-06-03 1988-06-02 Purification of tpa ZA883905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5692787A 1987-06-03 1987-06-03

Publications (1)

Publication Number Publication Date
ZA883905B true ZA883905B (en) 1989-12-27

Family

ID=22007415

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA883905A ZA883905B (en) 1987-06-03 1988-06-02 Purification of tpa

Country Status (6)

Country Link
EP (1) EP0294132A3 (fr)
JP (1) JPS63317082A (fr)
AU (1) AU1668988A (fr)
DK (1) DK295988A (fr)
PT (1) PT87641B (fr)
ZA (1) ZA883905B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH082301B2 (ja) * 1987-12-04 1996-01-17 三井東圧化学株式会社 逆相液体クロマトグラフィーによるｔ−ＰＡ精製方法
WO1991013976A1 (fr) * 1990-03-14 1991-09-19 Yamanouchi Pharmaceutical Co., Ltd. Procede pour la production d'un activateur plasminogene de tissus purifie ou de ses derives
DE19610092A1 (de) * 1996-03-15 1997-09-18 Focke & Co Verfahren und Einrichtung zum Ausrichten von Maschinen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984001714A1 (fr) * 1982-10-29 1984-05-10 Mitsui Toatsu Chemicals Nouvel activateur de plasminogene, son procede de preparation et medicament thrombolytique le contenant
DK175327B1 (da) * 1984-10-01 2004-08-23 Integrated Genetics Inc Replicerbar ekspressionsvektor og rekombinant DNA-molekyle, som indkoder aktiv human livmodervævsplasminogen-aktivator, pattedyrscelle transformeret med vektoren og fremgangsmåde til fremstilling af aktiv human vævsplasminogen-aktivator (TPA)
AU606582B2 (en) * 1985-09-06 1991-02-14 Codon Methods for the recovery of tissue plasminogen activator

Also Published As

Publication number Publication date
PT87641A (pt) 1988-07-01
DK295988D0 (da) 1988-05-31
JPS63317082A (ja) 1988-12-26
AU1668988A (en) 1988-12-08
DK295988A (da) 1988-12-04
PT87641B (pt) 1992-09-30
EP0294132A3 (fr) 1990-02-07
EP0294132A2 (fr) 1988-12-07

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