PT87641A - Process for isolate and purify concerning a tissue plasminogen activator - Google Patents

Process for isolate and purify concerning a tissue plasminogen activator

Info

Publication number
PT87641A
PT87641A PT87641A PT8764188A PT87641A PT 87641 A PT87641 A PT 87641A PT 87641 A PT87641 A PT 87641A PT 8764188 A PT8764188 A PT 8764188A PT 87641 A PT87641 A PT 87641A
Authority
PT
Portugal
Prior art keywords
purify
isolate
concerning
plasminogen activator
tissue plasminogen
Prior art date
Application number
PT87641A
Other languages
English (en)
Other versions
PT87641B (pt
Inventor
Peter Arletti Dephillips
Samuel Gregg Franklin
Kyung Oh Johanson
Patrick Joseph Mcdevitt
Robert David Sitrin
James Edward Strickler
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of PT87641A publication Critical patent/PT87641A/pt
Publication of PT87641B publication Critical patent/PT87641B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT87641A 1987-06-03 1988-06-01 Processo para isolar e purificar activador de plasminogenio tecidual PT87641B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5692787A 1987-06-03 1987-06-03

Publications (2)

Publication Number Publication Date
PT87641A true PT87641A (pt) 1988-07-01
PT87641B PT87641B (pt) 1992-09-30

Family

ID=22007415

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87641A PT87641B (pt) 1987-06-03 1988-06-01 Processo para isolar e purificar activador de plasminogenio tecidual

Country Status (6)

Country Link
EP (1) EP0294132A3 (pt)
JP (1) JPS63317082A (pt)
AU (1) AU1668988A (pt)
DK (1) DK295988A (pt)
PT (1) PT87641B (pt)
ZA (1) ZA883905B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH082301B2 (ja) * 1987-12-04 1996-01-17 三井東圧化学株式会社 逆相液体クロマトグラフィーによるｔ−ＰＡ精製方法
WO1991013976A1 (en) * 1990-03-14 1991-09-19 Yamanouchi Pharmaceutical Co., Ltd. Process for producing purified tissue plasminogen activator or its derivative
DE19610092A1 (de) * 1996-03-15 1997-09-18 Focke & Co Verfahren und Einrichtung zum Ausrichten von Maschinen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984001714A1 (en) * 1982-10-29 1984-05-10 Mitsui Toatsu Chemicals Novel plasminogen activator, process for its preparation, and thrombolytic drug containing the same
NO175158C (no) * 1984-10-01 1994-09-07 Genzyme Corp Fremstilling av human livmorsvevplasminogenaktivator med rekombinant-DNA
EP0238551A4 (en) * 1985-09-06 1988-02-01 Codon METHODS OF RECOVERING A TISSUE PLASMINOGEN ACTIVATOR.

Also Published As

Publication number Publication date
PT87641B (pt) 1992-09-30
DK295988A (da) 1988-12-04
DK295988D0 (da) 1988-05-31
ZA883905B (en) 1989-12-27
EP0294132A3 (en) 1990-02-07
EP0294132A2 (en) 1988-12-07
JPS63317082A (ja) 1988-12-26
AU1668988A (en) 1988-12-08

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920316

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040916