ZA879280B - Basically substituted phenylacetonitriles,their preparation and drugs containing these compounds - Google Patents

Basically substituted phenylacetonitriles,their preparation and drugs containing these compounds

Info

Publication number
ZA879280B
ZA879280B ZA879280A ZA879280A ZA879280B ZA 879280 B ZA879280 B ZA 879280B ZA 879280 A ZA879280 A ZA 879280A ZA 879280 A ZA879280 A ZA 879280A ZA 879280 B ZA879280 B ZA 879280B
Authority
ZA
South Africa
Prior art keywords
compounds
preparation
drugs containing
basically substituted
substituted phenylacetonitriles
Prior art date
Application number
ZA879280A
Other languages
English (en)
Inventor
Werner Seitz
Seitz Werner
Liliane Unger
Unger Liliane
Manfred Raschack
Raschack Manfred
Verena Baldinger
Baldinger Verena
Klaus Ruebsamen
Ruebsamen Klaus
Josef Gries
Gries Josef
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA879280B publication Critical patent/ZA879280B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ZA879280A 1986-12-11 1987-12-10 Basically substituted phenylacetonitriles,their preparation and drugs containing these compounds ZA879280B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863642331 DE3642331A1 (de) 1986-12-11 1986-12-11 Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA879280B true ZA879280B (en) 1989-08-30

Family

ID=6315963

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA879280A ZA879280B (en) 1986-12-11 1987-12-10 Basically substituted phenylacetonitriles,their preparation and drugs containing these compounds

Country Status (9)

Country Link
US (1) US4940780A (ja)
EP (1) EP0271013B1 (ja)
JP (1) JP2569088B2 (ja)
AT (1) ATE90339T1 (ja)
AU (1) AU611113B2 (ja)
CA (1) CA1337991C (ja)
DE (1) DE3642331A1 (ja)
ES (1) ES2054650T3 (ja)
ZA (1) ZA879280B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR862558B (en) * 1985-10-18 1987-02-12 Searle & Co Bicyclo-substituted phenylacetonitrile derivatives
CH676845A5 (ja) * 1986-11-07 1991-03-15 Oreal
GB8823203D0 (en) * 1988-10-04 1988-11-09 Pfizer Ltd Therapeutic agents
PT96283A (pt) * 1989-12-21 1991-09-30 Searle & Co Metodos de utilizacao de 2-isopropil-2-fenilaminovaleronitrilos como imunossupressores e vasodilatadores
US5162569A (en) * 1989-12-21 1992-11-10 G. D. Searle & Co. Phenylacetonitrilealkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives
IE904628A1 (en) * 1989-12-21 1991-07-17 Searle & Co w-Amino-Ó-Phenylalkanonitrile Derivatives
US5223536A (en) * 1991-07-23 1993-06-29 Fmc Corporation 1,4-diaryl-1-cyclopropyl-4-substituted butanes as insecticides and acaricides
FR2717473B1 (fr) * 1994-03-16 1996-06-28 Esteve Labor Dr Dérivés de cyclopropylacétonitrile, leur préparation et leur application comme médicaments.
DE19502967A1 (de) * 1995-01-31 1996-08-01 Basf Ag Verfahren zur Racemattrennung von 2-Aryl-2-omega-alkylaminoalkannitrilen
US5859279A (en) * 1996-09-10 1999-01-12 Darwin Discovery Limited Compound and process
GB9618835D0 (en) * 1996-09-10 1996-10-23 Chiroscience Ltd Process
WO2000055122A1 (fr) 1999-03-16 2000-09-21 Eisai Co., Ltd. Derives de nitrile
JPWO2003082234A1 (ja) * 2002-03-28 2005-07-28 株式会社資生堂 フェニルアセトニトリル誘導体及びこれを含有する養毛剤、皮膚外用剤

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA916157A (en) * 1972-12-05 Dengel Ferdinand Basically substituted phenylacetonitriles and method for their preparation
FR1449564A (fr) * 1962-04-02 1966-05-06 Knoll Ag Procédé de préparation de phénylacétronitriles substitués par des groupes basiques
NL127712C (ja) * 1964-12-21
DE1493904A1 (de) * 1965-07-31 1969-06-19 Knoll Ag Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
DE1643429A1 (de) * 1967-09-20 1971-01-28 Knoll Ag Basisch substituierte Phenylacetonitrile und Verfahren zu deren Herstellung
GB1202750A (en) * 1967-12-11 1970-08-19 Knoll Ag Substituted phenylacetonitriles
US4003914A (en) * 1973-12-21 1977-01-18 Hoffmann-La Roche Inc. Sulphur containing derivatives
CH611614A5 (en) * 1973-12-21 1979-06-15 Hoffmann La Roche Process for the preparation of heterocyclic compounds
DE2509797C2 (de) * 1975-03-06 1985-07-18 Dr. Karl Thomae Gmbh, 7950 Biberach Phthalimidine, deren physiologisch verträgliche Säureadditionssalze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
AT345806B (de) * 1975-03-06 1978-10-10 Thomae Gmbh Dr K Verfahren zur herstellung neuer substituierter arylalkylamine und deren salze
DE2631222C3 (de) * 1976-07-12 1979-01-04 Knoll Ag, 6700 Ludwigshafen Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
DE3144150A1 (de) * 1981-04-10 1982-12-09 Basf Ag, 6700 Ludwigshafen (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel
DE3138488A1 (de) * 1981-09-28 1983-04-14 Knoll Ag, 6700 Ludwigshafen Verwendung von basisch substituierten phenylacetonritrilen bei der vorbeugenden bekaempfung von krankheiten und mittel dafuer
JPS59304A (ja) * 1982-06-23 1984-01-05 Agency Of Ind Science & Technol 水−アルコ−ル分離膜の製造方法
JPS59146001A (ja) * 1983-02-09 1984-08-21 Seiko Epson Corp 眼鏡レンズ
DE3344755A1 (de) * 1983-12-10 1985-06-20 Basf Ag, 6700 Ludwigshafen 1,7-diphenyl-3-methylaza-7-cyan-8-methyl-nonan zur verwendung bei der bekaempfung von krankheiten
DE3409612A1 (de) * 1984-03-16 1985-09-19 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte isochromane und oxepine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE3433383A1 (de) * 1984-09-12 1986-03-20 Boehringer Mannheim Gmbh, 6800 Mannheim Neue phenyl-acetonitril-derivate
US4612329A (en) * 1984-10-17 1986-09-16 Hokuriku Pharmaceutical Co., Ltd. Pharmaceutical alpha-aminoalkyl-alpha-alkylphenylacetonitriles
GB8426738D0 (en) * 1984-10-23 1984-11-28 Scras Pyridine derivatives
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
US4593042A (en) * 1985-10-18 1986-06-03 G. D. Searle & Co. Bicyclo-substituted phenylacetonitrile derivatives
GR862558B (en) * 1985-10-18 1987-02-12 Searle & Co Bicyclo-substituted phenylacetonitrile derivatives
DE3603032A1 (de) * 1986-01-31 1987-08-06 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0271013A2 (de) 1988-06-15
AU8240387A (en) 1988-06-16
EP0271013B1 (de) 1993-06-09
JP2569088B2 (ja) 1997-01-08
JPS63156763A (ja) 1988-06-29
CA1337991C (en) 1996-01-23
EP0271013A3 (en) 1990-01-24
ATE90339T1 (de) 1993-06-15
ES2054650T3 (es) 1994-08-16
AU611113B2 (en) 1991-06-06
US4940780A (en) 1990-07-10
DE3642331A1 (de) 1988-06-23

Similar Documents

Publication Publication Date Title
SE8700498D0 (sv) Novel pharmaceologically active compounds
IE862554L (en) Pharmaceutical compositions
IL82084A0 (en) 1,4-diazepines,their preparation and pharmaceutical compositions containing them
ZA879280B (en) Basically substituted phenylacetonitriles,their preparation and drugs containing these compounds
ZA90966B (en) Oxidized diphenylheteroalkanes,the preparation and use thereof
ZA863382B (en) Quinolylglycinamide derivatives,the process for preparation thereof and their therapeutic application as psychotropic drugs
AU584235B2 (en) New tricyclic compounds, processes for the preparation thereof and pharmaceutical compositions containing them
EP0307814A3 (en) Tetracyclic quinazoline derivatives, preparation and use
EP0231003A3 (en) Basic substituted phenylacetonitriles, their preparation and medicaments containing them
ZA828639B (en) Novel triazoloquinazolinones, their preparation and pharmaceutical formulations containing these compounds
ZA90962B (en) Phenylhydrazones,the manufacture thereof and therapeutic and cosmetic compositions prepared therefrom
ZA826453B (en) Tricyclic thiazolyloxamic acids and their derivatives,their preparation,and therapeutic agents containing these compounds
HUT49876A (en) Process for producing 6-oxopyridazine derivatives and pharmaceutical compositions comprising same
IL65493A0 (en) Phenethanolamine derivatives,their preparation and pharmaceutical compositions containing them
DE2966809D1 (en) 3,4-diaza-bicyclo(4.1.0)hepten-2-ones-5, process for their preparation and therapeutical compositions containing them
IL82925A0 (en) Tetrahydrobenzothiazoles,their preparation and pharmaceutical compositions containing them
ZA869156B (en) Phenylacetaldehydes substituted by basic groups,their preparation and drugs containing these compounds
ZA83856B (en) Thiazaspirane derivatives,processes for their preparation,and medicaments
HUT54682A (en) Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds
ES2027507A6 (es) Procedimiento de preparacion de derivados selenofenicos.
IT1254745B (it) Ciclofosfazeni contenenti gruppi di acido acetil salicilico, procedimento di preparazione ed utilizzazione
IE862894L (en) Pharmaceutical compositions