ZA87389B - Pyrrolo(1,2-a)(4,1)benzoxazepine derivatives - Google Patents

Pyrrolo(1,2-a)(4,1)benzoxazepine derivatives

Info

Publication number
ZA87389B
ZA87389B ZA87389A ZA87389A ZA87389B ZA 87389 B ZA87389 B ZA 87389B ZA 87389 A ZA87389 A ZA 87389A ZA 87389 A ZA87389 A ZA 87389A ZA 87389 B ZA87389 B ZA 87389B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
image
represents hydrogen
halogen
pyrrolo
Prior art date
Application number
ZA87389A
Other languages
English (en)
Inventor
Jan William Francis Wasley
Jon Norman
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA87389B publication Critical patent/ZA87389B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA87389A 1986-01-21 1987-01-20 Pyrrolo(1,2-a)(4,1)benzoxazepine derivatives ZA87389B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/821,110 US4758559A (en) 1986-01-21 1986-01-21 Pyrrolo[1,2-a] [4,1]benzoxazepine derivatives useful as calmodulin and histamine inhibitors

Publications (1)

Publication Number Publication Date
ZA87389B true ZA87389B (en) 1987-11-25

Family

ID=25232538

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA87389A ZA87389B (en) 1986-01-21 1987-01-20 Pyrrolo(1,2-a)(4,1)benzoxazepine derivatives

Country Status (25)

Country Link
US (1) US4758559A (fi)
EP (1) EP0233483B1 (fi)
JP (2) JPH0780888B2 (fi)
KR (1) KR900004148B1 (fi)
AT (1) ATE62244T1 (fi)
AU (1) AU598510B2 (fi)
CA (1) CA1273335A (fi)
CY (1) CY1749A (fi)
DD (1) DD257430A5 (fi)
DE (1) DE3768978D1 (fi)
DK (1) DK169239B1 (fi)
ES (1) ES2039363T3 (fi)
FI (1) FI86636C (fi)
GR (1) GR3001737T3 (fi)
HK (1) HK24194A (fi)
HU (1) HU198061B (fi)
IE (1) IE59653B1 (fi)
IL (1) IL81302A (fi)
MA (1) MA20857A1 (fi)
MY (1) MY100914A (fi)
PH (1) PH25148A (fi)
PT (1) PT84136B (fi)
TN (1) TNSN87003A1 (fi)
ZA (1) ZA87389B (fi)
ZW (1) ZW787A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69332792T2 (de) * 1992-04-20 2004-01-15 Takeda Chemical Industries Ltd 4,1-Benzoxazepinderivate als Squalen-Synthetase Inhibitoren und ihre Verwendung zur Behandlung von Hypercholesterämie und als Fungizide
US5452434A (en) * 1992-07-14 1995-09-19 Advanced Micro Devices, Inc. Clock control for power savings in high performance central processing units
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
US5439524A (en) * 1993-04-05 1995-08-08 Vlsi Technology, Inc. Plasma processing apparatus
US5698518A (en) * 1994-03-30 1997-12-16 Oklahoma Medical Research Foundation Method for regulating inflammation and tumor growth with calmodulin, calmodulin analogues or calmodulin antagonists
US5624902A (en) * 1995-06-07 1997-04-29 Torrey Pines Institute For Molecular Studies Peptide inhibitors of calmodulin
US6423329B1 (en) 1999-02-12 2002-07-23 The Procter & Gamble Company Skin sanitizing compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053599A (en) * 1976-02-26 1977-10-11 American Hoechst Corporation Piperazionalkylpyrrolobenzoxazalkanes
US4029672A (en) * 1976-02-26 1977-06-14 American Hoechst Corporation Aminoalkylpyrrolobenzoxazalkanes
US4045448A (en) * 1976-02-26 1977-08-30 American Hoechst Corporation Pyrrolo[2,1-c][1,4]benzoxazepine and benzoxazocine derivatives
US4169095A (en) * 1977-01-19 1979-09-25 American Hoechst Corporation Process for preparing aminoalkylpyrrolobenzoxazalkanes
US4608374A (en) * 1983-11-07 1986-08-26 Hoechst-Roussel Pharmaceuticals Inc. 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents

Also Published As

Publication number Publication date
MA20857A1 (fr) 1987-10-01
AU6781387A (en) 1987-07-23
MY100914A (en) 1991-05-31
DK169239B1 (da) 1994-09-19
FI86636B (fi) 1992-06-15
FI86636C (fi) 1992-09-25
US4758559A (en) 1988-07-19
IL81302A0 (en) 1987-08-31
ZW787A1 (en) 1987-08-12
PT84136A (en) 1987-02-01
DE3768978D1 (de) 1991-05-08
JPH0826028B2 (ja) 1996-03-13
TNSN87003A1 (fr) 1990-01-01
JPS62169791A (ja) 1987-07-25
CY1749A (en) 1994-06-03
AU598510B2 (en) 1990-06-28
GR3001737T3 (en) 1992-11-23
PT84136B (pt) 1989-07-31
JPH0789966A (ja) 1995-04-04
IE870139L (en) 1987-07-21
KR870007181A (ko) 1987-08-17
CA1273335A (en) 1990-08-28
DK29587D0 (da) 1987-01-20
EP0233483A2 (de) 1987-08-26
JPH0780888B2 (ja) 1995-08-30
KR900004148B1 (ko) 1990-06-16
IE59653B1 (en) 1994-03-09
HU198061B (en) 1989-07-28
DD257430A5 (de) 1988-06-15
PH25148A (en) 1991-03-13
DK29587A (da) 1987-07-22
FI870207A (fi) 1987-07-22
EP0233483B1 (de) 1991-04-03
FI870207A0 (fi) 1987-01-19
ES2039363T3 (es) 1995-04-01
IL81302A (en) 1990-11-29
HUT45259A (en) 1988-06-28
HK24194A (en) 1994-03-25
EP0233483A3 (en) 1988-10-19
ATE62244T1 (de) 1991-04-15

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