ZA873896B - Novel triazine salt - Google Patents

Novel triazine salt

Info

Publication number
ZA873896B
ZA873896B ZA873896A ZA873896A ZA873896B ZA 873896 B ZA873896 B ZA 873896B ZA 873896 A ZA873896 A ZA 873896A ZA 873896 A ZA873896 A ZA 873896A ZA 873896 B ZA873896 B ZA 873896B
Authority
ZA
South Africa
Prior art keywords
novel triazine
triazine salt
salt
novel
dichlorophenyl
Prior art date
Application number
ZA873896A
Other languages
English (en)
Inventor
David Alan Sawyer
Alan Sawyer David
Frederick Charles Copp
Charles Copp Frederick
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZA873896B publication Critical patent/ZA873896B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA873896A 1986-05-30 1987-05-29 Novel triazine salt ZA873896B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868613183A GB8613183D0 (en) 1986-05-30 1986-05-30 Triazine salt

Publications (1)

Publication Number Publication Date
ZA873896B true ZA873896B (en) 1989-01-25

Family

ID=10598692

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA873896A ZA873896B (en) 1986-05-30 1987-05-29 Novel triazine salt

Country Status (18)

Country Link
US (1) US4847249A (fi)
EP (1) EP0247892B1 (fi)
JP (1) JPH0751571B2 (fi)
KR (1) KR910002254B1 (fi)
AT (1) ATE62902T1 (fi)
AU (1) AU597982B2 (fi)
CA (1) CA1286670C (fi)
DE (1) DE3769516D1 (fi)
DK (1) DK166278C (fi)
ES (1) ES2021709B3 (fi)
FI (1) FI90770C (fi)
GB (1) GB8613183D0 (fi)
GR (1) GR3001942T3 (fi)
HU (1) HU196769B (fi)
IE (1) IE60626B1 (fi)
IL (1) IL82710A (fi)
NZ (1) NZ220497A (fi)
ZA (1) ZA873896B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9012312D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
GB2257363B (en) * 1991-01-30 1994-09-28 Wellcome Found Water dispersible tablets containing acyclovir
GB9124807D0 (en) * 1991-11-22 1992-01-15 Wellcome Found Pharmaceutical formulations
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
GB9203483D0 (en) * 1992-02-19 1992-04-08 Wellcome Found Anti-inflammatory compounds
WO1993025207A1 (en) * 1992-06-12 1993-12-23 The Wellcome Foundation Limited Use of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine isethionate for the treatment and prevention of dependence, tolerance and sensitization of drugs
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
FR2699078B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application de la lamotrigine dans le traitement de lésions neurologiques liées à des traumatismes.
FR2700117B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens.
FR2702148B1 (fr) * 1993-03-05 1995-04-07 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement du neuro-sida.
GB9305693D0 (en) * 1993-03-19 1993-05-05 Wellcome Found Therapeutic triazine compounds and use
US5866597A (en) * 1993-03-19 1999-02-02 Glaxo Wellcome Inc. Use of triazine compounds for the treatment of memory and learning disorders
GB9306639D0 (en) * 1993-03-30 1993-05-26 Tocris Neuramin Limited Organic compounds
FR2702149B1 (fr) * 1993-06-03 1995-04-07 Rhone Poulenc Rorer Sa Application de la lamotrigine dans le traitement du neuro-sida.
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
GB9812413D0 (en) 1998-06-10 1998-08-05 Glaxo Group Ltd Compound and its use
CA2334937C (en) * 1998-12-14 2004-09-21 Torrent Pharmaceuticals Ltd. An improved process for the preparation of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
AU763244B2 (en) * 2000-01-03 2003-07-17 Rpg Life Sciences Limited A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine
IL134730A (en) * 2000-02-25 2003-10-31 Chemagis Ltd Process for preparing substituted benzoyl cyanide amidinohydrazones
WO2002068398A1 (en) * 2001-02-27 2002-09-06 Teva Pharmaceutical Industries Ltd. New crystal forms of lamotrigine and processes for their preparations
WO2003090693A2 (en) * 2002-04-23 2003-11-06 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing lamotrigine particles of defined morphology
HU225667B1 (en) * 2002-09-20 2007-05-29 Richter Gedeon Nyrt Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
ES2209639B1 (es) 2002-10-31 2005-08-01 Vita Cientifica, S.L. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y obtencion de su intermedio.
GB2395483A (en) * 2003-07-03 2004-05-26 Jubilant Organosys Ltd Crystalline lamotrigine and its monohydrate
US8486927B2 (en) * 2007-11-09 2013-07-16 Thar Pharmaceuticals Crystalline forms of lamotrigine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK153787C (da) * 1979-06-01 1989-01-16 Wellcome Found Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved
EP0086502B1 (en) * 1979-08-16 1987-03-25 The Wellcome Foundation Limited Substituted aromatic triazines
EP0093186B1 (en) * 1982-05-03 1986-07-09 Richardson Vicks Limited Pharmaceutical preparation for the topical treatment of acne
GB8328757D0 (en) * 1983-10-27 1983-11-30 Wellcome Found Chemical compounds

Also Published As

Publication number Publication date
FI872406A (fi) 1987-12-01
HU196769B (en) 1989-01-30
JPS62289570A (ja) 1987-12-16
FI90770C (fi) 1994-03-25
EP0247892A1 (en) 1987-12-02
KR910002254B1 (ko) 1991-04-08
AU7368487A (en) 1987-12-03
AU597982B2 (en) 1990-06-14
US4847249A (en) 1989-07-11
DK275987A (da) 1987-12-01
IL82710A0 (en) 1987-11-30
FI872406A0 (fi) 1987-05-29
GR3001942T3 (en) 1992-11-23
KR870011112A (ko) 1987-12-21
CA1286670C (en) 1991-07-23
NZ220497A (en) 1990-05-28
FI90770B (fi) 1993-12-15
IL82710A (en) 1992-01-15
JPH0751571B2 (ja) 1995-06-05
DE3769516D1 (de) 1991-05-29
IE871415L (en) 1987-11-30
IE60626B1 (en) 1994-07-27
DK166278C (da) 1993-08-23
DK275987D0 (da) 1987-05-29
EP0247892B1 (en) 1991-04-24
GB8613183D0 (en) 1986-07-02
HUT45978A (en) 1988-09-28
DK166278B (da) 1993-03-29
ATE62902T1 (de) 1991-05-15
ES2021709B3 (es) 1991-11-16

Similar Documents

Publication Publication Date Title
ZA873896B (en) Novel triazine salt
HK159395A (en) Use of 1,3-oxathiolane nucleoside analogues in the manufacture of a medicament for treatment of hepatitis b
DE3466668D1 (en) Process for the decomposition of s-triazine derivatives in aqueous solutions
GB2202536B (en) Triazine compounds derived from 2,2,6,6-tetramethylpiperidine
EG18453A (en) Five membered heterocyclic derivatives of n'-substituted-n,n'-diacylhidrazines
GR3004303T3 (fi)
GB2277265A (en) Use of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine for the treatment of pain and oedema
IL78735A0 (en) Process for preparing 6-amino-3-hydrazinopyridazine derivatives
YU48589A (en) Process for improved preparation of4,4'-dinitro-stilbene-2,2'-disulphonic acid and it's salts
PT86006A (en) Process for the preparation of 2-aminomethyl-5-(2-biphenylyl)-1,3,4-thiadiazole
DE3363560D1 (en) Finely pulverized 2,4-diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine and pharmaceutically acceptable acid addition salts thereof
GR3007204T3 (fi)
GR871510B (en) Paracetamole stable aqueous solutions for injection
PH20413A (en) Crystalline human leukocyte interferon
GB2246792B (en) Electrochemical process for preparing 4,4'-dinitrostilbene-2,2'-disulfonic acid and the salts thereof
GB8629711D0 (en) Triazine derivatives
IL72268A0 (en) 6-(2,3-dimethyl-but-2-yl)-1,2,4-triazin-5-one derivatives,their preparation and their use as herbicides
IE870863L (en) 1,3,5-triazine derivatives
RO102375A2 (ro) Procedeu de alchilare a 2-cian-2-hidroxiiminoacetamidei (cianacetamidoximei)
IT8522214V0 (it) Bottone del tipo detto "automatico" avente anche una funzione di gancio per un bloccaggio stabile delle due parti del bottone.
IT7819422A0 (it) Procedimento per la produzione di tetraidro-1,2,4-triazine 3-sostituite e composti di questo tipo
IT1182606B (it) Metodo e dispositivo per effettuare mediante laser trattamenti termici con distribuzione uniforme di potenza