ZA873083B - Diastereoisomeric tetrahydropyrido(2,3-d)pyrimidine derivatives - Google Patents

Diastereoisomeric tetrahydropyrido(2,3-d)pyrimidine derivatives

Info

Publication number
ZA873083B
ZA873083B ZA873083A ZA873083A ZA873083B ZA 873083 B ZA873083 B ZA 873083B ZA 873083 A ZA873083 A ZA 873083A ZA 873083 A ZA873083 A ZA 873083A ZA 873083 B ZA873083 B ZA 873083B
Authority
ZA
South Africa
Prior art keywords
tetrahydropyrido
diastereoisomeric
pyrimidine derivatives
pyrimidine
derivatives
Prior art date
Application number
ZA873083A
Other languages
English (en)
Inventor
C. Taylor Edward
Peter Beardsley George
Shih Chuan
R. Fletcher Stephen
Original Assignee
The Trustees Of Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Trustees Of Princeton University filed Critical The Trustees Of Princeton University
Publication of ZA873083B publication Critical patent/ZA873083B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA873083A 1986-06-06 1987-04-29 Diastereoisomeric tetrahydropyrido(2,3-d)pyrimidine derivatives ZA873083B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87153986A 1986-06-06 1986-06-06

Publications (1)

Publication Number Publication Date
ZA873083B true ZA873083B (en) 1987-10-26

Family

ID=25357673

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA873083A ZA873083B (en) 1986-06-06 1987-04-29 Diastereoisomeric tetrahydropyrido(2,3-d)pyrimidine derivatives

Country Status (15)

Country Link
EP (1) EP0248573A3 (ko)
JP (1) JPH07116190B2 (ko)
KR (1) KR950004894B1 (ko)
CN (1) CN1019391B (ko)
AU (1) AU592182B2 (ko)
CA (1) CA1301155C (ko)
DK (1) DK170023B1 (ko)
EG (1) EG19551A (ko)
ES (1) ES2003828A6 (ko)
GR (1) GR870783B (ko)
NZ (1) NZ219971A (ko)
PH (1) PH25509A (ko)
PT (1) PT84990B (ko)
SU (1) SU1627087A3 (ko)
ZA (1) ZA873083B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60038B1 (en) * 1986-06-30 1994-05-18 Univ Princeton 4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
US4895946A (en) * 1987-10-26 1990-01-23 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US4889859A (en) * 1988-02-05 1989-12-26 The Trustees Of Princeton University Pyrido[2,3-d]pyrimidine derivatives
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
US5223620A (en) * 1988-04-01 1993-06-29 Takeda Chemical Industries, Ltd. Pyrido[2,3-d]pyrimidine compounds useful as intermediates
DK172753B1 (da) * 1988-05-25 1999-06-28 Lilly Co Eli N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
US5008391A (en) * 1989-07-07 1991-04-16 Eli Lilly And Company Enantioselective synthesis of antifolates
US5066828A (en) * 1990-04-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
JP2002503648A (ja) * 1998-02-11 2002-02-05 イーライ・リリー・アンド・カンパニー 葉酸拮抗薬を製造するのに有用な方法および中間体
CN110749692B (zh) * 2019-10-15 2022-03-18 扬子江药业集团有限公司 L-谷氨酸二乙酯盐酸盐及其光学异构体的分离检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA861235B (en) * 1985-03-08 1986-10-29 Univ Princeton Pyrido(2,3-d)pyrimidine derivatives

Also Published As

Publication number Publication date
EG19551A (en) 1996-02-29
CA1301155C (en) 1992-05-19
KR950004894B1 (ko) 1995-05-15
JPS6339878A (ja) 1988-02-20
AU7273187A (en) 1987-12-10
GR870783B (en) 1987-09-25
SU1627087A3 (ru) 1991-02-07
PH25509A (en) 1991-07-24
DK232387D0 (da) 1987-05-06
PT84990B (pt) 1990-03-08
JPH07116190B2 (ja) 1995-12-13
CN87104103A (zh) 1987-12-30
NZ219971A (en) 1989-08-29
EP0248573A2 (en) 1987-12-09
PT84990A (en) 1987-07-01
AU592182B2 (en) 1990-01-04
DK170023B1 (da) 1995-05-01
KR880000431A (ko) 1988-03-25
DK232387A (da) 1987-12-07
ES2003828A6 (es) 1988-11-16
CN1019391B (zh) 1992-12-09
EP0248573A3 (en) 1989-06-14

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