ZA869057B - Nonaromatic fluoroallylamine mao inhibitors - Google Patents

Nonaromatic fluoroallylamine mao inhibitors

Info

Publication number
ZA869057B
ZA869057B ZA869057A ZA869057A ZA869057B ZA 869057 B ZA869057 B ZA 869057B ZA 869057 A ZA869057 A ZA 869057A ZA 869057 A ZA869057 A ZA 869057A ZA 869057 B ZA869057 B ZA 869057B
Authority
ZA
South Africa
Prior art keywords
fluoroallylamine
nonaromatic
mao inhibitors
mao
inhibitors
Prior art date
Application number
ZA869057A
Other languages
English (en)
Inventor
Philippe Bey
Ian A Mcdonald
Michael G Palfreyman
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA869057B publication Critical patent/ZA869057B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/24Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/46Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA869057A 1985-12-05 1986-12-01 Nonaromatic fluoroallylamine mao inhibitors ZA869057B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/805,506 US4650907A (en) 1985-12-05 1985-12-05 Nonaromatic fluoroallylamine MAO inhibitors

Publications (1)

Publication Number Publication Date
ZA869057B true ZA869057B (en) 1987-07-29

Family

ID=25191744

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA869057A ZA869057B (en) 1985-12-05 1986-12-01 Nonaromatic fluoroallylamine mao inhibitors

Country Status (16)

Country Link
US (1) US4650907A (es)
KR (1) KR900006125B1 (es)
CN (1) CN1014515B (es)
AR (1) AR242948A1 (es)
AU (1) AU594722B2 (es)
CA (1) CA1265818C (es)
DK (1) DK167763B1 (es)
FI (1) FI86845C (es)
HU (1) HU199394B (es)
IE (1) IE59058B1 (es)
IL (1) IL80817A (es)
NO (1) NO165916C (es)
NZ (1) NZ218498A (es)
PH (1) PH22545A (es)
PT (1) PT83864B (es)
ZA (1) ZA869057B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI890827A (fi) * 1988-02-25 1989-08-26 Merrell Dow Pharma Lysyloxidas-inhibitorer.
US5059714A (en) * 1988-02-25 1991-10-22 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5252608A (en) * 1988-02-25 1993-10-12 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5169868A (en) * 1991-03-01 1992-12-08 University Of Saskatchewan Aliphatic propargylamines as specific mao-b inhibitors
CN1794988B (zh) * 2003-03-31 2010-07-28 株式会社·R-技术上野 用于治疗血管渗透性过高疾病的组合物
DE602005013793D1 (de) * 2004-07-27 2009-05-20 Astellas Pharma Inc Thiazolderivate mit vap-1-hemmender wirkung
WO2006028269A2 (en) * 2004-09-09 2006-03-16 Astellas Pharma Inc. Thiazole derivatives having vap-1 ihibitory activity
WO2009066152A2 (en) * 2007-11-21 2009-05-28 Pharmaxis Ltd. Haloallylamine inhibitors of ssao/vap-1 and uses therefor
CA2871793C (en) 2012-05-02 2020-09-15 Pharmaxis Ltd. Substituted 3-haloallylamine inhibitors of ssao and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454158A (en) * 1981-06-01 1984-06-12 Merrell Toraude Et Compagnie Allyl amine MAO inhibitors

Also Published As

Publication number Publication date
DK583486D0 (da) 1986-12-04
DK167763B1 (da) 1993-12-13
NO864869D0 (no) 1986-12-04
AU6581386A (en) 1987-06-11
FI864962A0 (fi) 1986-12-04
IE59058B1 (en) 1993-12-15
KR870005960A (ko) 1987-07-08
FI86845B (fi) 1992-07-15
AR242948A1 (es) 1993-06-30
AU594722B2 (en) 1990-03-15
HU199394B (en) 1990-02-28
CN86108051A (zh) 1987-08-19
FI864962A (fi) 1987-06-06
NO864869L (no) 1987-06-09
PT83864A (en) 1987-01-01
IL80817A0 (en) 1987-03-31
NZ218498A (en) 1989-09-27
CA1265818A (en) 1990-02-13
CN1014515B (zh) 1991-10-30
PT83864B (pt) 1989-01-17
IL80817A (en) 1991-06-10
HUT46293A (en) 1988-10-28
DK583486A (da) 1987-06-06
NO165916C (no) 1991-05-02
US4650907A (en) 1987-03-17
KR900006125B1 (ko) 1990-08-24
NO165916B (no) 1991-01-21
CA1265818C (en) 1990-02-13
FI86845C (fi) 1992-10-26
PH22545A (en) 1988-10-17
IE863186L (en) 1987-06-05

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