FI864962A - Icke-aromatiska fluorallylamin-mao-inhibitorer. - Google Patents

Icke-aromatiska fluorallylamin-mao-inhibitorer. Download PDF

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Publication number
FI864962A
FI864962A FI864962A FI864962A FI864962A FI 864962 A FI864962 A FI 864962A FI 864962 A FI864962 A FI 864962A FI 864962 A FI864962 A FI 864962A FI 864962 A FI864962 A FI 864962A
Authority
FI
Finland
Prior art keywords
fluorallylamin
inhibitorer
icke
mao
aromatic
Prior art date
Application number
FI864962A
Other languages
English (en)
Other versions
FI864962A0 (fi
FI86845B (fi
FI86845C (fi
Inventor
Philippe Bey
Ian A Mcdonald
Michael G Palfreyman
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI864962A0 publication Critical patent/FI864962A0/fi
Publication of FI864962A publication Critical patent/FI864962A/fi
Publication of FI86845B publication Critical patent/FI86845B/fi
Application granted granted Critical
Publication of FI86845C publication Critical patent/FI86845C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/24Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/46Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI864962A 1985-12-05 1986-12-04 Foerfarande foer framstaellning av en terapeutiskt anvaendbar fluorallylamin FI86845C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80550685 1985-12-05
US06/805,506 US4650907A (en) 1985-12-05 1985-12-05 Nonaromatic fluoroallylamine MAO inhibitors

Publications (4)

Publication Number Publication Date
FI864962A0 FI864962A0 (fi) 1986-12-04
FI864962A true FI864962A (fi) 1987-06-06
FI86845B FI86845B (fi) 1992-07-15
FI86845C FI86845C (fi) 1992-10-26

Family

ID=25191744

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864962A FI86845C (fi) 1985-12-05 1986-12-04 Foerfarande foer framstaellning av en terapeutiskt anvaendbar fluorallylamin

Country Status (16)

Country Link
US (1) US4650907A (fi)
KR (1) KR900006125B1 (fi)
CN (1) CN1014515B (fi)
AR (1) AR242948A1 (fi)
AU (1) AU594722B2 (fi)
CA (1) CA1265818A (fi)
DK (1) DK167763B1 (fi)
FI (1) FI86845C (fi)
HU (1) HU199394B (fi)
IE (1) IE59058B1 (fi)
IL (1) IL80817A (fi)
NO (1) NO165916C (fi)
NZ (1) NZ218498A (fi)
PH (1) PH22545A (fi)
PT (1) PT83864B (fi)
ZA (1) ZA869057B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5252608A (en) * 1988-02-25 1993-10-12 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
NZ228068A (en) * 1988-02-25 1991-11-26 Merrell Dow Pharma Brominated or chlorinated allylamines and their pharmaceutical compositions
US5059714A (en) * 1988-02-25 1991-10-22 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5169868A (en) * 1991-03-01 1992-12-08 University Of Saskatchewan Aliphatic propargylamines as specific mao-b inhibitors
CA2520957C (en) * 2003-03-31 2013-08-06 Sucampo Ag Method for treating vascular hyperpermeable disease
JP4978464B2 (ja) * 2004-07-27 2012-07-18 アステラス製薬株式会社 Vap−1阻害剤活性を有するチアゾール誘導体
EP1791835A2 (en) * 2004-09-09 2007-06-06 Astellas Pharma Inc. Thiazole derivatives having vap-1 inhibitory activity
JP2011504485A (ja) * 2007-11-21 2011-02-10 ファーマクシス リミテッド Ssao/vap−1のハロアリルアミン阻害剤およびその用途
AU2013255103B2 (en) 2012-05-02 2016-09-29 Pharmaxis Ltd. Substituted 3-haloallylamine inhibitors of SSAO and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454158A (en) * 1981-06-01 1984-06-12 Merrell Toraude Et Compagnie Allyl amine MAO inhibitors

Also Published As

Publication number Publication date
IL80817A0 (en) 1987-03-31
DK583486A (da) 1987-06-06
IE59058B1 (en) 1993-12-15
US4650907A (en) 1987-03-17
KR870005960A (ko) 1987-07-08
HUT46293A (en) 1988-10-28
CN86108051A (zh) 1987-08-19
IE863186L (en) 1987-06-05
AU594722B2 (en) 1990-03-15
AU6581386A (en) 1987-06-11
PH22545A (en) 1988-10-17
FI864962A0 (fi) 1986-12-04
HU199394B (en) 1990-02-28
CN1014515B (zh) 1991-10-30
ZA869057B (en) 1987-07-29
DK167763B1 (da) 1993-12-13
AR242948A1 (es) 1993-06-30
FI86845B (fi) 1992-07-15
NO864869D0 (no) 1986-12-04
NZ218498A (en) 1989-09-27
DK583486D0 (da) 1986-12-04
KR900006125B1 (ko) 1990-08-24
NO165916B (no) 1991-01-21
NO864869L (no) 1987-06-09
PT83864B (pt) 1989-01-17
CA1265818C (en) 1990-02-13
NO165916C (no) 1991-05-02
IL80817A (en) 1991-06-10
FI86845C (fi) 1992-10-26
PT83864A (en) 1987-01-01
CA1265818A (en) 1990-02-13

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: MERRELL DOW PHARMACEUTICALS INC.