ZA867988B - Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzene-acetic acids,salts and esters - Google Patents

Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzene-acetic acids,salts and esters

Info

Publication number
ZA867988B
ZA867988B ZA867988A ZA867988A ZA867988B ZA 867988 B ZA867988 B ZA 867988B ZA 867988 A ZA867988 A ZA 867988A ZA 867988 A ZA867988 A ZA 867988A ZA 867988 B ZA867988 B ZA 867988B
Authority
ZA
South Africa
Prior art keywords
inflammation
pain
esters
salts
amino
Prior art date
Application number
ZA867988A
Other languages
English (en)
Inventor
Richard George Poser
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of ZA867988B publication Critical patent/ZA867988B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA867988A 1985-10-28 1986-10-21 Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzene-acetic acids,salts and esters ZA867988B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/792,269 US4683242A (en) 1985-10-28 1985-10-28 Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters

Publications (1)

Publication Number Publication Date
ZA867988B true ZA867988B (en) 1987-06-24

Family

ID=25156312

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA867988A ZA867988B (en) 1985-10-28 1986-10-21 Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzene-acetic acids,salts and esters

Country Status (12)

Country Link
US (1) US4683242A (de)
EP (1) EP0221753B1 (de)
JP (1) JPH07116027B2 (de)
AT (1) ATE71358T1 (de)
AU (1) AU596813B2 (de)
DE (1) DE3683350D1 (de)
ES (1) ES2039354T3 (de)
GR (1) GR3004278T3 (de)
HU (1) HU197210B (de)
IE (1) IE59229B1 (de)
PH (1) PH22410A (de)
ZA (1) ZA867988B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3620674A1 (de) * 1986-06-20 1987-12-23 Nattermann A & Cie Salbe zur behandlung von hauterkrankungen
US4782089A (en) * 1986-08-26 1988-11-01 A. H. Robins Company, Incorporated 2-amino-3-aroyl-gamma-oxobenzenebutanoic acids and esters
CA1325382C (en) 1988-01-27 1993-12-21 Takahiro Ogawa Locally administrable therapeutic composition for inflammatory disease
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
DK1051972T3 (da) 1994-05-27 2008-01-28 Strakan Int Ltd Nitrogenoxiddonorsammensætning og fremgangsmåde til behandling af anale lidelser
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
DE19631220C2 (de) * 1996-08-02 2000-03-23 Beiersdorf Ag Schaumförmige oder schäumbare Zubereitungen mit einem Gehalt an grenzflächenaktiven Substanzen und Elektrolyten
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US20060015058A1 (en) * 1998-01-08 2006-01-19 Kellogg Scott C Agents and methods for enhancement of transdermal transport
US8287483B2 (en) * 1998-01-08 2012-10-16 Echo Therapeutics, Inc. Method and apparatus for enhancement of transdermal transport
US7066884B2 (en) * 1998-01-08 2006-06-27 Sontra Medical, Inc. System, method, and device for non-invasive body fluid sampling and analysis
US20040171980A1 (en) 1998-12-18 2004-09-02 Sontra Medical, Inc. Method and apparatus for enhancement of transdermal transport
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US7186745B2 (en) 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
AU2002247284A1 (en) 2001-04-02 2002-10-15 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
WO2003092669A2 (en) * 2002-05-03 2003-11-13 Alcon, Inc. Method of treating vascular endothelial growth factor mediated vascular disorders using amfenac or nepafenac
ES2301964T3 (es) 2003-01-21 2008-07-01 Senju Pharmaceutical Co., Ltd. Preparado liquido acuoso que contiene acido 2-amino-3-(4-bromobenzoil)fenilacetico.
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
US8224414B2 (en) * 2004-10-28 2012-07-17 Echo Therapeutics, Inc. System and method for analyte sampling and analysis with hydrogel
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
TR201815853T4 (tr) 2005-10-12 2018-11-21 Besins Healthcare Sarl Hipogonadizmin tedavisinde kullanıma yönelik geliştirilmiş testosteron jeli.
US7432069B2 (en) * 2005-12-05 2008-10-07 Sontra Medical Corporation Biocompatible chemically crosslinked hydrogels for glucose sensing
TW200812575A (en) * 2006-04-28 2008-03-16 Alcon Inc Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
FR2909876A1 (fr) * 2006-12-19 2008-06-20 Galderma Res & Dev S N C Snc Utilisation du nepafenac ou ses derives pour le traitement de desordres dermatologiques
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
WO2008080110A1 (en) * 2006-12-21 2008-07-03 Alcon, Inc. Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
KR101433550B1 (ko) * 2007-03-07 2014-08-27 에코 테라퓨틱스, 인크. 경피 피분석물 모니터링 시스템 및 피분석물 검출 방법
CN101707872B (zh) * 2007-04-27 2014-10-22 回声治疗有限公司 用于分析物感测或经皮给药的皮肤渗透装置
GB0919757D0 (en) 2009-11-12 2009-12-30 Johnson Matthey Plc Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB2484843A (en) * 2009-10-15 2012-04-25 Johnson Matthey Plc Polymorphs of Bromfenac sodium
US8299295B2 (en) 2009-10-15 2012-10-30 Johnson Matthey Public Limited Company Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
CN104177272B (zh) * 2014-06-16 2016-04-06 广东众生药业股份有限公司 一种溴芬酸钠的制备方法
CN104151182B (zh) * 2014-06-16 2016-03-30 广东众生药业股份有限公司 一种溴芬酸钠倍半水合物的制备方法
CN106404952B (zh) * 2016-08-31 2019-06-11 辰欣佛都药业（汶上）有限公司 一种溴芬酸钠滴眼液有关物质的测定方法
CN115093340B (zh) * 2022-06-27 2024-05-03 辰欣药业股份有限公司 一种溴芬酸钠倍半水合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH577461A5 (de) * 1975-08-13 1976-07-15 Robins Co Inc A H
JPS53130634A (en) * 1977-04-20 1978-11-14 Hisamitsu Pharmaceut Co Inc Novel 2-(3-phenoxyphenyl) propionic acid ester derivatives
JPS596287B2 (ja) * 1980-11-28 1984-02-10 日東電工株式会社 医薬製剤
US4503073A (en) * 1981-01-07 1985-03-05 A. H. Robins Company, Incorporated 2-Amino-3-(alkylthiobenzoyl)-phenylacetic acids
IL64724A0 (en) * 1981-02-17 1982-03-31 Robins Co Inc A H 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
JPS5883622A (ja) * 1981-11-10 1983-05-19 Hisamitsu Pharmaceut Co Inc 消炎鎮痛ゲル状クリーム剤
WO1986002636A1 (en) * 1984-10-30 1986-05-09 Takeda Chemical Industries, Ltd. Benzoic acid derivatives and process for their preparation

Also Published As

Publication number Publication date
EP0221753A3 (en) 1988-04-27
AU596813B2 (en) 1990-05-17
JPS62126124A (ja) 1987-06-08
IE862811L (en) 1987-04-28
HU197210B (en) 1989-03-28
DE3683350D1 (de) 1992-02-20
PH22410A (en) 1988-08-26
EP0221753A2 (de) 1987-05-13
ES2039354T3 (es) 1996-07-16
IE59229B1 (en) 1994-01-26
US4683242A (en) 1987-07-28
GR3004278T3 (de) 1993-03-31
ATE71358T1 (de) 1992-01-15
JPH07116027B2 (ja) 1995-12-13
AU6444786A (en) 1987-04-30
EP0221753B1 (de) 1992-01-08
HUT42948A (en) 1987-09-28

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